Blocking of the interfaces of polymeric ion sensors - implications for novel sensor applications. Control of the transmembrane fluxes of polymeric ion sensors represents a paradigm shift that has revolutionised the use of these analytically important devices. This project will develop and characterise innovative methods for controlling these fluxes by using blocked interfaces, and this has important ramifications for the development of robust and reliable sensors, as well as novel biosensors.
A reliable physical model of molecular motion in crystals. The scientific benefits would flow, in the first instance, to the large national and international communities of scientists whose research makes use of the results of X-ray diffraction experiments. Applications of the research to amino acids and peptides will benefit investigations into the structure and molecular dynamics of biological systems, including proteins and enzymes. Studies of charge densities in crystals will obtain a standa ....A reliable physical model of molecular motion in crystals. The scientific benefits would flow, in the first instance, to the large national and international communities of scientists whose research makes use of the results of X-ray diffraction experiments. Applications of the research to amino acids and peptides will benefit investigations into the structure and molecular dynamics of biological systems, including proteins and enzymes. Studies of charge densities in crystals will obtain a standard tool for improved modelling of molecular motion, resulting in physically more realistic charge density functions, and hence greater insight into the relationship between properties of crystals and their constituent molecules.Read moreRead less
The role of water uptake in novel all solid-state polymeric ion sensors. This research will enable the development of robust all solid-state polymeric ion sensors based on unplasticized copolymers. Significantly, the physical and chemical robustness of these copolymer ion sensors will allow their widespread use in new and exciting analytical applications, e.g., in-situ analysis of environmental samples in submersible instruments, clinical analysis of whole blood, in-vivo use of miniaturized ele ....The role of water uptake in novel all solid-state polymeric ion sensors. This research will enable the development of robust all solid-state polymeric ion sensors based on unplasticized copolymers. Significantly, the physical and chemical robustness of these copolymer ion sensors will allow their widespread use in new and exciting analytical applications, e.g., in-situ analysis of environmental samples in submersible instruments, clinical analysis of whole blood, in-vivo use of miniaturized electrodes in biological media, especially single cells and minute samples in biology and forensic science, etc. Extensive use of neutron characterization techniques aligns strongly this project with the new OPAL reactor to be commissioned in 2007.Read moreRead less
Accessory Mineral Microstructure and Implications for Geochronology. U-Pb geochronology of accessory minerals is widely used to constrain the timing of igneous, metamorphic and sedimentary processes. However, our current knowledge of isotope mobility in these important minerals cannot readily explain some common features of U-Pb dating. Using new developments in quantitative microstructural analysis integrated with high spatial resolution geochronology we will constrain the relationship between ....Accessory Mineral Microstructure and Implications for Geochronology. U-Pb geochronology of accessory minerals is widely used to constrain the timing of igneous, metamorphic and sedimentary processes. However, our current knowledge of isotope mobility in these important minerals cannot readily explain some common features of U-Pb dating. Using new developments in quantitative microstructural analysis integrated with high spatial resolution geochronology we will constrain the relationship between accessory minerals deformation and its effect on radiometric ages. Our results will lead to a better understanding of geochemical modification of accessory minerals and may lead to the development of new applications of geochronology and improve the dating of rock deformation.Read moreRead less
Evolution of a two billion year subduction zone: Insights from the integration of microstructure and geochronology. The dynamic evolution of the earth is fundamentally linked to its thermal history. Since, the internal heat production of the earth has changed over time, plate tectonic processes may also have changed over earth history. The manner and timing of this change is highly controversial. We aim to address the nature of tectonic processes 2 billion years ago by studying one of the wor ....Evolution of a two billion year subduction zone: Insights from the integration of microstructure and geochronology. The dynamic evolution of the earth is fundamentally linked to its thermal history. Since, the internal heat production of the earth has changed over time, plate tectonic processes may also have changed over earth history. The manner and timing of this change is highly controversial. We aim to address the nature of tectonic processes 2 billion years ago by studying one of the world's oldest subduction zones (the Usagarian belt in Tanzania). The geometry, kinematics and deformation history of the subduction complex will be integrated with radiometric age dating to quantify the style and rates of ancient tectonic processes.Read moreRead less