Multifunctional Structural Panels for Next-generation Infrastructure. This project aims to develop a multifunctional prefabricated structural panel for current and future infrastructure applications for both land and offshore environments. Prefabrication enables enhanced product control as well as the ability to rapidly construct whole structures or their components. The panels utilise an inner lightweight foam and fibre-reinforced polymer (FRP) composite core with strong outer panels made from ....Multifunctional Structural Panels for Next-generation Infrastructure. This project aims to develop a multifunctional prefabricated structural panel for current and future infrastructure applications for both land and offshore environments. Prefabrication enables enhanced product control as well as the ability to rapidly construct whole structures or their components. The panels utilise an inner lightweight foam and fibre-reinforced polymer (FRP) composite core with strong outer panels made from FRP sheets and high-strength concrete. The expected outcomes include experimental and numerical validation of the system, that will give designers and asset owners the confidence to adopt this new panel. The panel system presents an upward step change in construction technology and built infrastructure performance.Read moreRead less
Structural Fuses for Safer and More Economical Bridge Construction. This project aims to develop a novel structural system leading to more economical concrete bridge construction by utilising a customised structural fuse. A significant margin of safety is required in structural design to account for accidental over-loading and to reduce the risk of structural collapse. Such a margin leads to more material usage. Incorporation of a fuse into the structure that is triggered upon over-loading will ....Structural Fuses for Safer and More Economical Bridge Construction. This project aims to develop a novel structural system leading to more economical concrete bridge construction by utilising a customised structural fuse. A significant margin of safety is required in structural design to account for accidental over-loading and to reduce the risk of structural collapse. Such a margin leads to more material usage. Incorporation of a fuse into the structure that is triggered upon over-loading will cause a safer failure mode and prohibit further increase of loading, both of which result in a reduced structure without undermining safety. The project is expected to advance structural theory, and also provide significant benefits to the construction industry via cost reduction and more eco-friendly constructions.Read moreRead less
Composite tubular construction subject to impact and blast loading. This project will advance the knowledge of composite tubular members and connections under impact and blast loading. It will provide confident design methodology against impact and blast loading for buildings designated as prominent targets or items of critical infrastructure, to save lives and reduce losses.
A new angle on the coalescence of drops. Many processes depend on what happens when drops and/or bubbles collide with each other, or with the surfaces of other materials. Examples include inkjet printing, agricultural spraying, spray coating of paints, pharmaceutical formulation, stability of cosmetics and foodstuffs, formation of froths and foams, and flow of bubbly liquids. To control these processes, we need to understand how and why drops sometimes do and sometimes do not coalesce with each ....A new angle on the coalescence of drops. Many processes depend on what happens when drops and/or bubbles collide with each other, or with the surfaces of other materials. Examples include inkjet printing, agricultural spraying, spray coating of paints, pharmaceutical formulation, stability of cosmetics and foodstuffs, formation of froths and foams, and flow of bubbly liquids. To control these processes, we need to understand how and why drops sometimes do and sometimes do not coalesce with each other or adhere to surfaces. The knowledge gained in this project will enable improvements to be made in the efficiency of processes such as those listed above.Read moreRead less
Detection of infrared-biomarkers for the diagnosis and treatment of canine neoplasia. This research hopes to discover infrared-biomarkers for canine cancers using synchrotron infrared and laser light. Many dog cancers are similar to human cancers so cancerous tissues and cells from dogs make excellent models for human cancer research. This project will provide new insights and technological approaches to cancer diagnosis and treatment.
Human Leukocyte Antigen-A and -B regulation of Natural Killer cell function. The aim of this project is to determine how genetic variation in the genes encoding cell surface receptors expressed by innate lymphocytes and the molecules they recognise diversifies their capacity to sense and respond to infection. This knowledge is critical for understanding why there are intrinsic differences between individuals with respect to their capacity to respond to different types of infection and will ultim ....Human Leukocyte Antigen-A and -B regulation of Natural Killer cell function. The aim of this project is to determine how genetic variation in the genes encoding cell surface receptors expressed by innate lymphocytes and the molecules they recognise diversifies their capacity to sense and respond to infection. This knowledge is critical for understanding why there are intrinsic differences between individuals with respect to their capacity to respond to different types of infection and will ultimately inform our capacity to better deploy personalised medicines.Read moreRead less
Smart hybrid nano-biomaterials that mimic the pharmaceutical food effect. Smart biomaterials will be developed which when taken orally will act in our gut to improve drug and vitamin uptake. The breakthrough science will drive new pharmaceuticals and nutraceuticals for the future health of Australia, and economic benefits will result through increased exposure to the global market for delivering biomolecules.
Harnessing lipid nano-assembly for next generation functional foods and pharmaceutical products. Nature assembles lipid molecules from our diet into useful structures in our gastrointestinal tract with remarkable precision and versatility. By understanding and harnessing these processes we can design new lipid-based nanomaterials leading to more effective functional foods and pharmaceutical products with reduced side effects.
Hydrogen carbon waste into concrete: AI assisted nanoscience approach. The carbon waste from hydrogen production will be converted into carbon nanosheets on abundant construction materials for the creation of stronger and more durable concrete. Cutting-edge nanoscience-based experiments, as well as sophisticated modelling techniques including machine learning and finite element modelling, will be employed. The findings will drive advances in clean hydrogen production, carbon waste utilisation, c ....Hydrogen carbon waste into concrete: AI assisted nanoscience approach. The carbon waste from hydrogen production will be converted into carbon nanosheets on abundant construction materials for the creation of stronger and more durable concrete. Cutting-edge nanoscience-based experiments, as well as sophisticated modelling techniques including machine learning and finite element modelling, will be employed. The findings will drive advances in clean hydrogen production, carbon waste utilisation, cement hydration, nanotechnology and concrete technology for the next generation of an upskilled workforce and the promotion of a circular economy. This project will be carried out in collaboration with Australian and international renowned experts in computational modelling, nanomaterials and concrete materials.Read moreRead less
Nanoscale characterisation of the dynamics of artificial lipid membranes - model systems for drug binding studies. This project will see the development of artificial membranes replicating the physiological behaviour of cell membranes providing a novel platform for in vitro drug evaluation clearing the way for the development of effective new therapies with fewer side effects.