ARC Molecular and Materials Structure Research Network. The Network will build powerful e-Science resources for the structural sciences. Collaborative remote access will be developed for sophisticated instrumentation, including instruments planned for the Replacement Research Reactor and Australian Synchrotron. A structure database service with cross disciplinary content and versatile visualisation and analysis capabilities will further exemplify smart information use. The internet services will ....ARC Molecular and Materials Structure Research Network. The Network will build powerful e-Science resources for the structural sciences. Collaborative remote access will be developed for sophisticated instrumentation, including instruments planned for the Replacement Research Reactor and Australian Synchrotron. A structure database service with cross disciplinary content and versatile visualisation and analysis capabilities will further exemplify smart information use. The internet services will ultimately harness the Grid, enabling linkage into other national and international Grid systems. Encompassing physics, computer science, applied mathematics, chemistry and biochemistry, and catalysing interaction across these disciplines, the MMSN will impact all five National Research Priority 3 goals.Read moreRead less
Advanced matrix-analytic methods with applications. Over the last twenty-five years, matrix-analytic methods have proved to be very successful in formulating and analysing certain classes of stochastic models. Motivated by applications, this project will investigate more advanced matrix-analytic methods than have hitherto been studied.
ARC Centre of Excellence - Australian Centre for Electromaterials Science. The Centre will tackle some of the biggest challenges facing society: those of renewable energy, sustainable industries and enhancing human health. Improvements in all these areas are possible by developing electromaterials with improved efficiency in the generation and transfer of electrical charge. By developing new nano-materials and new theories to explain their behaviour, the Centre will make advances in the areas ....ARC Centre of Excellence - Australian Centre for Electromaterials Science. The Centre will tackle some of the biggest challenges facing society: those of renewable energy, sustainable industries and enhancing human health. Improvements in all these areas are possible by developing electromaterials with improved efficiency in the generation and transfer of electrical charge. By developing new nano-materials and new theories to explain their behaviour, the Centre will make advances in the areas of human health through the regeneration of damaged nerves (eg. in spinal injury) and development of artificial muscles; in renewable energy (plastic solar cells, lightweight batteries and electronic textiles) and in sustainable industries (recovery of precious metals and new corrosion protection technologies).Read moreRead less
Identification Of Glaucoma Susceptibility Variants By Exome Sequencing In Extended Pedigrees Showing Prior Evidence Of Gene Segregation.
Funder
National Health and Medical Research Council
Funding Amount
$694,002.00
Summary
Primary open angle glaucoma is a chronic eye disease and one of the leading causes of visual impairment and blindness worldwide. This study will use cutting-edge genetic methods to look at the entire coding component of the human genome (exome) in 271 individuals from large glaucoma families. Our previous studies have shown that these families carry genetic variants that increase disease risk. In this investigation we aim to identify these genes, with the hope they may offer novel targets for tr ....Primary open angle glaucoma is a chronic eye disease and one of the leading causes of visual impairment and blindness worldwide. This study will use cutting-edge genetic methods to look at the entire coding component of the human genome (exome) in 271 individuals from large glaucoma families. Our previous studies have shown that these families carry genetic variants that increase disease risk. In this investigation we aim to identify these genes, with the hope they may offer novel targets for treatment or diagnosis.Read moreRead less
Change Detection in Causal Relationships and Measurement of Systemic Risk. Empirical measures of interconnectedness between financial institutions based on tests of Granger causality are currently used in detecting systemic risk. However, researchers need to define periods of calm and stress exogenously in order to implement these tests appropriately. This project aims to develop a new procedure to identify changes in causal relationships and the timing of these changes. The new approach has the ....Change Detection in Causal Relationships and Measurement of Systemic Risk. Empirical measures of interconnectedness between financial institutions based on tests of Granger causality are currently used in detecting systemic risk. However, researchers need to define periods of calm and stress exogenously in order to implement these tests appropriately. This project aims to develop a new procedure to identify changes in causal relationships and the timing of these changes. The new approach has the potential to be a significant improvement in the real-time identification of emerging turmoil in financial markets and provide an improved method for the detection of systemic risk. The new test procedure will be implemented using data for financial and non-financial institutions across Europe, the US and Australia.Read moreRead less
Geologic, genetic and exploration implications of syndeformational, structurally-controlled, sediment-hosted copper deposits: investigation of the Mt Oxide deposit, Queensland. This project will use a multi-disciplinary approach to understand the geology, geochemistry and genesis of the syndeformational, structurally-controlled, sediment-hosted copper mineralisation at the Mt Oxide deposit, Queensland. Copper deposits, like Mt Oxide, are an important exploration target in sedimentary basins but ....Geologic, genetic and exploration implications of syndeformational, structurally-controlled, sediment-hosted copper deposits: investigation of the Mt Oxide deposit, Queensland. This project will use a multi-disciplinary approach to understand the geology, geochemistry and genesis of the syndeformational, structurally-controlled, sediment-hosted copper mineralisation at the Mt Oxide deposit, Queensland. Copper deposits, like Mt Oxide, are an important exploration target in sedimentary basins but their characteristics and formation are poorly understood. Discovery of further sediment-hosted Cu deposits is imperative as Australia's industrial competitivness in exploration and mining depends on the discovery of new ore depsoits. This project specifically addresses the need for better genetic and exploration models for copper deposits concealed within ancient, deformed sedimentary sequences in Australia and overseas.Read moreRead less
Origin and setting of Congolese-type Cu deposits. This project aims to understand the genesis of the giant sediment-hosted Cu ore deposits of the Congolese Copperbelt, and their relationship to the enclosing strata. We will use selected study areas within the correlative Neoproterozic basin successions in Australia, which are well exposed and covered by modern geoscientific datasets, as analogues for the poorly exposed Congolese system. Once this is achieved, we will combine the results with tho ....Origin and setting of Congolese-type Cu deposits. This project aims to understand the genesis of the giant sediment-hosted Cu ore deposits of the Congolese Copperbelt, and their relationship to the enclosing strata. We will use selected study areas within the correlative Neoproterozic basin successions in Australia, which are well exposed and covered by modern geoscientific datasets, as analogues for the poorly exposed Congolese system. Once this is achieved, we will combine the results with those of a previous ARC linkage project on the nearby Zambian Copperbelt, to provide the first integrated model of the worlds largest sedimentary Cu system.Read moreRead less
Tectonic geography of the world's oldest petroleum play, the McArthur Basin. This projects aims to develop a 4D tectonic geography framework to support the effective exploration of the McArthur Basin. This project will construct this by a) investigating the evolving tectonic setting, b) examining intra-basin correlations and trace the source to sink sediment provenance, c) unraveling the depositional geography using novel isotopic proxies, and, d) constructing the subsequent thermal history of ....Tectonic geography of the world's oldest petroleum play, the McArthur Basin. This projects aims to develop a 4D tectonic geography framework to support the effective exploration of the McArthur Basin. This project will construct this by a) investigating the evolving tectonic setting, b) examining intra-basin correlations and trace the source to sink sediment provenance, c) unraveling the depositional geography using novel isotopic proxies, and, d) constructing the subsequent thermal history of the basin. The techniques developed through this project will de-risk the exploration for petroleum in this basin, and be applicable in opening up Proterozoic petroleum elsewhere in Australia and internationally.Read moreRead less
Hybrid Remote Area Power Systems with Hydrogen Energy Storage for Isolated and Regional Communities. The distances and difficulties of transporting diesel to remote areas substantially add to the cost of electricity - making it many times the cost of supplies available from the grid. Consistency of electricity supply is dependent on reliable transport access and substantial storage for fuel on site. This project will reduce emissions in energy generation and provide the opportunity for mainly ....Hybrid Remote Area Power Systems with Hydrogen Energy Storage for Isolated and Regional Communities. The distances and difficulties of transporting diesel to remote areas substantially add to the cost of electricity - making it many times the cost of supplies available from the grid. Consistency of electricity supply is dependent on reliable transport access and substantial storage for fuel on site. This project will reduce emissions in energy generation and provide the opportunity for mainly renewable, high-quality electricity supplies at reduced cost for remote and isolated communities. This will make communities more self-sufficient, enhance the quality of life and provide opportunities for initiatives, including economic and employment generating activities, to benefit the communities.Read moreRead less
Optimising Control of Hydroelectric Turbines Subject to Basslink Instability. With the introduction of Basslink, an underwater DC power cable across the Bass Strait, Tasmania will be connected to the national Electricity Market. Basslink will also provide an opportunity to utilise the significant water energy potential found throughout Tasmania. This project will examine the impact and disturbances due to the connection of Basslink with Tasmanian hydro power systems and develop control strategi ....Optimising Control of Hydroelectric Turbines Subject to Basslink Instability. With the introduction of Basslink, an underwater DC power cable across the Bass Strait, Tasmania will be connected to the national Electricity Market. Basslink will also provide an opportunity to utilise the significant water energy potential found throughout Tasmania. This project will examine the impact and disturbances due to the connection of Basslink with Tasmanian hydro power systems and develop control strategies for effective operation and control of hydro turbines with Basslink. Particular attention will be paid to the quality and reliability of electricity supply in Tasmania.Read moreRead less