Meso- and Macro-porous Bioactive Glasses for Bone-repairing. This project aims to use self-assembly and pore engineering at different length scales to fabricate novel bioactive glasses of highly ordered mesoporous structure. By precisely controlling the composition, size and volume of both mesopores and macropores, bioactive glasses with improved bone forming activities will be obtained. The successful synthesis of such bioactive glasses is expected to lead to the fundamental understanding of st ....Meso- and Macro-porous Bioactive Glasses for Bone-repairing. This project aims to use self-assembly and pore engineering at different length scales to fabricate novel bioactive glasses of highly ordered mesoporous structure. By precisely controlling the composition, size and volume of both mesopores and macropores, bioactive glasses with improved bone forming activities will be obtained. The successful synthesis of such bioactive glasses is expected to lead to the fundamental understanding of structure-bioactivity relationship, and new materials effective for tissue engineering. This will also open up new opportunities for other applications such as drug delivery, implanting.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE140100012
Funder
Australian Research Council
Funding Amount
$890,000.00
Summary
Dual Column-Focused Ion Beam/Scanning Electron Microscope facility for Queensland. Dual column focused ion beam/scanning electron microscope facility: This facility will precisely cut specimens and surfaces that can be imaged in a variety of ways, including crystallographic and elemental space, of particular use for physical scientists, as well as biological specimens. This instrument will provide information at resolutions between optical and transmission electron microscopy, images that will ....Dual Column-Focused Ion Beam/Scanning Electron Microscope facility for Queensland. Dual column focused ion beam/scanning electron microscope facility: This facility will precisely cut specimens and surfaces that can be imaged in a variety of ways, including crystallographic and elemental space, of particular use for physical scientists, as well as biological specimens. This instrument will provide information at resolutions between optical and transmission electron microscopy, images that will effectively provide the biologist with the ability to develop the complete correlative picture of organelles and cells. The instrument will also provide a much needed resource for researchers across disciplines such as physics, chemistry, biology, geology and engineering.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100036
Funder
Australian Research Council
Funding Amount
$440,000.00
Summary
National in-situ transmission electron microscope facilities. This project will establish six complementary transmission electron microscope (TEM) facilities at various locations. The establishment of the facilities will be a key step in developing advanced capacity in Australia and will support ground-breaking research in diverse material systems for various high-performing applications, including electronics, optoelectronics, light metals, biomaterials, energy, and environment.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100139
Funder
Australian Research Council
Funding Amount
$350,000.00
Summary
A Hot Isostatic Press (HIP) for aerospace and biomedical component processing. This facility will provide a hot isostatic press of sufficiently large capacity to maximise production efficiencies in aerospace and biomedical applications through net shape manufacturing. The facility will be able to process small components or prototypes which will behave in a manner similar to larger scale components.
Beyond Microarrays: Nano-Scaled Devices for High Throughput Biomolecular Sensing. Current developments in Nanoscience and Nanotechnology hold many promises in terms of revolutionising our industrial base, transforming biology, medical science and practice. This project strives to achieve some of these aims by, for the first time, building and testing nano-scaled devices with the capability to 'read' massive amounts of biological information. With the recent completion of the Human Genome proje ....Beyond Microarrays: Nano-Scaled Devices for High Throughput Biomolecular Sensing. Current developments in Nanoscience and Nanotechnology hold many promises in terms of revolutionising our industrial base, transforming biology, medical science and practice. This project strives to achieve some of these aims by, for the first time, building and testing nano-scaled devices with the capability to 'read' massive amounts of biological information. With the recent completion of the Human Genome project, major opportunities exist to provide spectacular advances in human health care (eg, via personalised medicine) provided that appropriate high-throughput biological reading devices can be developed. In developing such devices, this project also aims to substantially catalyse the Australian Nanotechnology/Biotechnology industry.Read moreRead less
Design and Fabrication of an Engineered Bone Graft System (EBGS) by combining a composite scaffold and growth factor delivery system. The lifetime risk for long bone fractures in Caucasians over the age of 50 is 17% for women and 6% for men. The prevalence of age-related fractures - and with it higher mortality rates due to complications following bone fractures - is therefore bound to increase over the coming decades. There is clearly a great need for therapies that take age-related changes in ....Design and Fabrication of an Engineered Bone Graft System (EBGS) by combining a composite scaffold and growth factor delivery system. The lifetime risk for long bone fractures in Caucasians over the age of 50 is 17% for women and 6% for men. The prevalence of age-related fractures - and with it higher mortality rates due to complications following bone fractures - is therefore bound to increase over the coming decades. There is clearly a great need for therapies that take age-related changes into consideration, in particular the diminishing capacity of bone to heal with age. In an effort to address the therapeutic challenges of providing bone grafts, we aim to mesh two leading-edge technologies to design and fabricate an Engineered Bone Graft System (EBGS) system. Read moreRead less
Development and characterization of a technology platform to study the mechanisms of scaffold/Bone Morphogenic Proteins (BMP) augmented large segmental bone healing. This project will increase understanding of bone engineering and in doing so will lead to superior treatments for bone defects. Such a treatment would be valuable in addressing the ever-increasing problems of diminished productivity and reduced quality of life associated with bone disorders as the population ages. The multidisciplin ....Development and characterization of a technology platform to study the mechanisms of scaffold/Bone Morphogenic Proteins (BMP) augmented large segmental bone healing. This project will increase understanding of bone engineering and in doing so will lead to superior treatments for bone defects. Such a treatment would be valuable in addressing the ever-increasing problems of diminished productivity and reduced quality of life associated with bone disorders as the population ages. The multidisciplinary and international team will be valuable in establishing Australia's prominence in this field and training the next generation of young scientists and engineers. The technologies developed will be of great interest to a large number of research groups and companies worldwide and will assist with fostering international collaboration and placing Australia at the forefront of this emerging field.Read moreRead less
Frontiers in bone and joint regeneration. Key outcomes of this project will deliver innovative strategies for scaffold-based bone and cartilage engineering whilst contributing to the education of a new generation of bioengineers, biomaterial scientists and tissue engineers with a strong international profile.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0347937
Funder
Australian Research Council
Funding Amount
$300,000.00
Summary
Imaging Raman Spectrometer. An Imaging Raman spectrometer generates image maps 10x faster than older instruments and is required to meet escalating demand. This results from innovative use of Raman to characterise organics, polymers, thin films and biomaterials, which underpins rapidly evolving research in nanotechnology and biotechnology. Many innovations have come from QUT's Centre for Instrumental and Developmental Chemistry, which will host the spectrometer and is a key resource for all Qu ....Imaging Raman Spectrometer. An Imaging Raman spectrometer generates image maps 10x faster than older instruments and is required to meet escalating demand. This results from innovative use of Raman to characterise organics, polymers, thin films and biomaterials, which underpins rapidly evolving research in nanotechnology and biotechnology. Many innovations have come from QUT's Centre for Instrumental and Developmental Chemistry, which will host the spectrometer and is a key resource for all Queensland universities. The availability of its high quality spectroscopic facility has enabled leading edge developments by local companies and the Imaging Raman spectrometer will significantly accelerate and enhance current and future project outcomes.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0668532
Funder
Australian Research Council
Funding Amount
$680,000.00
Summary
A Focussed Ion Beam-Scanning Electron Microscope for Advanced Analytical and Nanotechnology Research in South East Queensland. The minerals industry underpins Australia's current economic prosperity. The aging of the population presents major economic challenges in the delivery of cost effective health services. New nanotechnology-enabled industries will contribute to future national economic and environmental well-being. The research enhanced by this facility impacts all these areas. It will i ....A Focussed Ion Beam-Scanning Electron Microscope for Advanced Analytical and Nanotechnology Research in South East Queensland. The minerals industry underpins Australia's current economic prosperity. The aging of the population presents major economic challenges in the delivery of cost effective health services. New nanotechnology-enabled industries will contribute to future national economic and environmental well-being. The research enhanced by this facility impacts all these areas. It will improve mineral extraction and processing, enhance fundamental understanding of cellular interactions with textured surfaces, and lead to improved implantable material designs and improved implantable device lifetimes (eg hip and knee replacements). Development of advanced nanotechnology applications in energy, optoelectronics and sensors will be also be extended.Read moreRead less