Development of efficient, robust and architecturally-flexible structural systems using innovative blind-bolted connections. The aim of the proposed project is to develop structural systems that have sufficient stiffness, strength, and ductility to withstand code-specified loads and that will be competitive in the marketplace. The development of demonstrable cost-effective structural systems is essential if these types of systems are to be widely adopted in practice, thus allowing Australian manu ....Development of efficient, robust and architecturally-flexible structural systems using innovative blind-bolted connections. The aim of the proposed project is to develop structural systems that have sufficient stiffness, strength, and ductility to withstand code-specified loads and that will be competitive in the marketplace. The development of demonstrable cost-effective structural systems is essential if these types of systems are to be widely adopted in practice, thus allowing Australian manufacturers of blind bolts and steel tubes to achieve a greater market share.Read moreRead less
Reinforced crumbed rubber concrete for residential construction. Reinforced crumbed rubber concrete for residential construction. This project aims to use crumb rubber from used tyres to replace natural sand aggregate in concrete used in housing construction. Globally, very few of the millions of tyres discarded annually are recycled, while natural sand used in concrete is being depleted. This project intends to provide the tyre industry with a viable market for end of life tyres, and the premix ....Reinforced crumbed rubber concrete for residential construction. Reinforced crumbed rubber concrete for residential construction. This project aims to use crumb rubber from used tyres to replace natural sand aggregate in concrete used in housing construction. Globally, very few of the millions of tyres discarded annually are recycled, while natural sand used in concrete is being depleted. This project intends to provide the tyre industry with a viable market for end of life tyres, and the premix concrete industry with a “green” product for the residential construction market. Expected benefits include the increased use of a waste resource (used tyres), reduced use of a scarce natural resource (sand), and the development of an economic but green alternative concrete option for residential builders and owners.Read moreRead less
Scalable Graphene Enabled Smart Composites. The need for lightweight composite materials is increasing exponentially in the context of renewable energy, e-mobility and related emission reductions. This project aims to develop novel approaches to integrate graphene nanomaterials into structural composites, enabling damage sensing and structural health monitoring functionalities. The outcome of this project will be a new class of smart composites that will address the critical need for improving s ....Scalable Graphene Enabled Smart Composites. The need for lightweight composite materials is increasing exponentially in the context of renewable energy, e-mobility and related emission reductions. This project aims to develop novel approaches to integrate graphene nanomaterials into structural composites, enabling damage sensing and structural health monitoring functionalities. The outcome of this project will be a new class of smart composites that will address the critical need for improving structural integrity, safety and reliability, while significantly reducing lifecycle costs. This should provide significant benefits in creating confidence to increase investment in Australia for manufacturing graphene enabled smart materials and technologies with enormous export potential.Read moreRead less
Enhanced sensitivity of electrospray ionization mass spectrometry. Enhanced sensitivity of electrospray ionization mass spectrometry. This project aims to enhance the sensitivity of nano-electrospray ionization mass spectrometry (nanoESI-MS) by an order of magnitude by simultaneously overcoming the two interdependent limitations in ion generation and transmission efficiency. This project will design glass capillaries and tubes with complex structures to enable both multiplexing ion generation fr ....Enhanced sensitivity of electrospray ionization mass spectrometry. Enhanced sensitivity of electrospray ionization mass spectrometry. This project aims to enhance the sensitivity of nano-electrospray ionization mass spectrometry (nanoESI-MS) by an order of magnitude by simultaneously overcoming the two interdependent limitations in ion generation and transmission efficiency. This project will design glass capillaries and tubes with complex structures to enable both multiplexing ion generation from a single capillary and geometrically matching the bore of the tube collecting the emitted ion plume. NanoESI-MS has become an indispensable analytical tool for proteomics and synthetic chemistry. The significant enhancement of nanoESI-MS sensitivity in this project is expected to accelerate progress in disease research, biomarker discovery and drug development.Read moreRead less
New insulins for the improved management of diabetes. The prevalence of diabetes has increased dramatically over the past few decades and now this condition is widely considered the world’s fastest growing disease. New insulins with improved pharmacological and storage properties are desperately needed, and this project will work on chemical synthesis enabling designer insulins to be prepared for improved management of diabetes.
Self-zoning in natural uraninite: radiation driven chemical separation. In this project we aim to explore and define the effects of the substitution of lead and rare earths on the crystal chemistry of uranium dioxide (uraninite) and related minerals, towards establishing the oxygen stoichiometry (as a measure of oxygen fugacity) of these materials both in nature and in synthetic materials. This project will use synthetic materials to understand the variability of oxygen stoichiometry, establish ....Self-zoning in natural uraninite: radiation driven chemical separation. In this project we aim to explore and define the effects of the substitution of lead and rare earths on the crystal chemistry of uranium dioxide (uraninite) and related minerals, towards establishing the oxygen stoichiometry (as a measure of oxygen fugacity) of these materials both in nature and in synthetic materials. This project will use synthetic materials to understand the variability of oxygen stoichiometry, establish accurate and precise structures for the oxides, and distinguish both long range and short-range order which is critical to understanding both natural and synthetic U-oxides. This will help to define the geochemical conditions leading to the formation of deposits like Olympic Dam towards potential economic benefit.Read moreRead less
Exploring the immunomodulatory potential of Natural Killer T cells. Natural Killer T cells (NKT cells) are an innate-like population of T cells that recognise a range of lipid based antigens when bound to the antigen-presenting molecule, CD1d. Once activated, NKT cells rapidly secrete a variety of cytokines. This project, in partnership with Vaxine Pty Ltd, aims to gain a basic understanding of NKT recognition of lipids and NKT cell activation by lipids. The project aims to use a combination of ....Exploring the immunomodulatory potential of Natural Killer T cells. Natural Killer T cells (NKT cells) are an innate-like population of T cells that recognise a range of lipid based antigens when bound to the antigen-presenting molecule, CD1d. Once activated, NKT cells rapidly secrete a variety of cytokines. This project, in partnership with Vaxine Pty Ltd, aims to gain a basic understanding of NKT recognition of lipids and NKT cell activation by lipids. The project aims to use a combination of cellular immunology and structural biology to gain insight into NKT cell agonism.Read moreRead less
Detecting developing cracks before pipe bursts using smart sensor systems. This project aims to significantly reduce the number of pipe bursts in cities by detecting the leaks from developing cracks on water supply pipes just in time. New techniques will be developed for reliable and timely detection using the existing sensor network in the Adelaide CBD. Specialised monitoring stations will be developed with adaptive noise-cancellation algorithms to detect small leak signals in noisy city enviro ....Detecting developing cracks before pipe bursts using smart sensor systems. This project aims to significantly reduce the number of pipe bursts in cities by detecting the leaks from developing cracks on water supply pipes just in time. New techniques will be developed for reliable and timely detection using the existing sensor network in the Adelaide CBD. Specialised monitoring stations will be developed with adaptive noise-cancellation algorithms to detect small leak signals in noisy city environments. Expected outcomes include an effective pipe burst early warning system and the implementation of an active burst prevention and targeted pipe replacement strategy. This should significantly reduce the burst rates and associated interruptions in Adelaide and save millions of dollars every year in pipe relay programs.Read moreRead less
Design guideline for suction caissons supporting offshore wind turbines. This project aims to develop an industry guideline for suction caisson foundations, that are a new form of fixed platform anchor, for offshore wind turbines. The project expects to generate new knowledge of caisson response during installation and over millions of wind/wave load cycles, by integrating field experience with measurements from innovative experiments. The expected outcomes of this project include new methods to ....Design guideline for suction caissons supporting offshore wind turbines. This project aims to develop an industry guideline for suction caisson foundations, that are a new form of fixed platform anchor, for offshore wind turbines. The project expects to generate new knowledge of caisson response during installation and over millions of wind/wave load cycles, by integrating field experience with measurements from innovative experiments. The expected outcomes of this project include new methods to guide suction installation in difficult soil layering and predicting rotation and stiffness over a turbine’s operational life. The benefits of these scientific advances will contribute to the economic and reliable design of suction caisson foundations and a more rapid take-up of offshore wind energy.Read moreRead less
Deciphering the tectonic history of the Musgrave Block to assist mineral explorers and regional synthesis programs. Effective mineral exploration strategies in complex basement terrains are increasingly reliant on integrated, data-rich, tectonic models. In this project we will focus a large multidisciplinary team to develop a tectonic model for the evolution of the Musgrave Block in central Australia. This large, poorly understood terrain occupies a critical structural location, separating the ....Deciphering the tectonic history of the Musgrave Block to assist mineral explorers and regional synthesis programs. Effective mineral exploration strategies in complex basement terrains are increasingly reliant on integrated, data-rich, tectonic models. In this project we will focus a large multidisciplinary team to develop a tectonic model for the evolution of the Musgrave Block in central Australia. This large, poorly understood terrain occupies a critical structural location, separating the northern and southern Australian cratons. By constraining models of crustal evolution and architecture, the project will underpin future mineral exploration programs in this highly prospective greenfields region and define the role of the Musgrave Block in the assembly of Proterozoic Australia.Read moreRead less