Understanding Australia by analysing wastewater during the Census 2021 . This project aims to utilise the Australian Census 2021, a unique opportunity to link exposure to chemical and biological hazards with catchment socio-demographic data via systematic wastewater analysis. The project is expected to advance our capabilities to identify emerging hazards and understand factors that affect spatiotemporal trends in hazards across Australia. Moreover, in a world first, the project aims to assess c ....Understanding Australia by analysing wastewater during the Census 2021 . This project aims to utilise the Australian Census 2021, a unique opportunity to link exposure to chemical and biological hazards with catchment socio-demographic data via systematic wastewater analysis. The project is expected to advance our capabilities to identify emerging hazards and understand factors that affect spatiotemporal trends in hazards across Australia. Moreover, in a world first, the project aims to assess chemical fate on a national level by linking sales/use with fate and release from wastewater treatment plants and assess treatment efficiency at >100 plants around Australia. The project expects to provide insight for government, wastewater managers and industry into hazards that may affect environmental and human health.Read moreRead less
Novel strategies in the design and development of antivirals against dengue virus. Globally, there are 50-100 million cases of dengue fever, with 500,000 cases of the more severe dengue haemorrhagic fever, each year. Australia has between 100 and 900 cases of dengue infection annually, often from travellers, but disease outbreaks occur in northern Australia. Effective anti-viral treatment will reduce disease burden. The project contributes to an evidence-based drug design program in collaboratio ....Novel strategies in the design and development of antivirals against dengue virus. Globally, there are 50-100 million cases of dengue fever, with 500,000 cases of the more severe dengue haemorrhagic fever, each year. Australia has between 100 and 900 cases of dengue infection annually, often from travellers, but disease outbreaks occur in northern Australia. Effective anti-viral treatment will reduce disease burden. The project contributes to an evidence-based drug design program in collaboration with Australia's leading biotechnology industries. As a biotechnology industry project developing treatments for an emerging disease, it contributes to the national research priorities of Frontier technologies for building and transforming Australian industries, Promoting and maintaining good health and Safeguarding Australia.Read moreRead less
Multi-functional nano-modified cementitious materials for well cementing. By incorporating different nano-materials in well cements, this project aims to develop multi-functional cementitious materials with self-sensing properties and greater strength and durability under extreme conditions including high/low temperatures, high pressure and corrosive environments. The integrity and longevity of well cement are paramount for the safe, efficient, environmentally sustainable production of oil and n ....Multi-functional nano-modified cementitious materials for well cementing. By incorporating different nano-materials in well cements, this project aims to develop multi-functional cementitious materials with self-sensing properties and greater strength and durability under extreme conditions including high/low temperatures, high pressure and corrosive environments. The integrity and longevity of well cement are paramount for the safe, efficient, environmentally sustainable production of oil and natural gas resources. Cementing problems are the main factor contributing to incidents during drilling and completion of wells, necessitating costly remediation. It is expected that the novel cement developed in the project will produce safer wells with fewer (gas) environmental emission risks.Read moreRead less
Reinforced crumbed rubber concrete for residential construction. Reinforced crumbed rubber concrete for residential construction. This project aims to use crumb rubber from used tyres to replace natural sand aggregate in concrete used in housing construction. Globally, very few of the millions of tyres discarded annually are recycled, while natural sand used in concrete is being depleted. This project intends to provide the tyre industry with a viable market for end of life tyres, and the premix ....Reinforced crumbed rubber concrete for residential construction. Reinforced crumbed rubber concrete for residential construction. This project aims to use crumb rubber from used tyres to replace natural sand aggregate in concrete used in housing construction. Globally, very few of the millions of tyres discarded annually are recycled, while natural sand used in concrete is being depleted. This project intends to provide the tyre industry with a viable market for end of life tyres, and the premix concrete industry with a “green” product for the residential construction market. Expected benefits include the increased use of a waste resource (used tyres), reduced use of a scarce natural resource (sand), and the development of an economic but green alternative concrete option for residential builders and owners.Read moreRead less
Seismic analysis of cracking and deformations in concrete gravity dams. This project aims to establish a rational predictive capability for the responses of concrete gravity dams subject to extreme design earthquakes. This will include the development of innovative numerical methods for effective modelling of crack propagation and closure, large slips on crack faces and weak interfaces, dam-reservoir interaction, dam-foundation interaction and automatic mesh generation. The expected outcomes of ....Seismic analysis of cracking and deformations in concrete gravity dams. This project aims to establish a rational predictive capability for the responses of concrete gravity dams subject to extreme design earthquakes. This will include the development of innovative numerical methods for effective modelling of crack propagation and closure, large slips on crack faces and weak interfaces, dam-reservoir interaction, dam-foundation interaction and automatic mesh generation. The expected outcomes of the project will be a significantly improved prediction tool. It is also anticipated that the project will result in improvements in dam and public safety, and more efficient use of funds for dam safety upgrades and management.Read moreRead less
Estimating use of tobacco and nicotine products through wastewater analysis. This project aims to equip the Australian public health and security sector with a tool to accurately measure tobacco consumption in the general population. Specific human biomarkers in urine will be identified using non-target approaches and their pharmacokinetics quantified. The new data will address critical gaps in our knowledge on the population-level excretion of biomarkers for the consumption of tobacco and alter ....Estimating use of tobacco and nicotine products through wastewater analysis. This project aims to equip the Australian public health and security sector with a tool to accurately measure tobacco consumption in the general population. Specific human biomarkers in urine will be identified using non-target approaches and their pharmacokinetics quantified. The new data will address critical gaps in our knowledge on the population-level excretion of biomarkers for the consumption of tobacco and alternative nicotine products. The outcomes of this project will provide reliable, cost-effective estimates of tobacco consumption for use with wastewater-based epidemiology assessments. This will enable changes in tobacco use to be accurately evaluated for the first time and improve the efficacy of tobacco control measures.Read moreRead less
Discovery and characterisation of novel spider-venom peptides targeting the human sodium ion channel Nav1.7. Drugs that selectively block the human sodium ion channel Nav1.7 are likely to be powerful analgesics for treating a wide variety of pain conditions. However, it has proved difficult to obtain selective blockers of this channel. The aim of this project is to determine whether spider-venoms might provide a source of highly selective Nav1.7 blockers.
Tailoring the microwave dielectric properties of promising electroceramics for use in wireless telecommunication components and devices. This project aims to develop and tailor the microwave dielectric properties of promising electroceramic materials specifically targeting next generation wireless telecommunications applications. The partnership between the ANU and the Australian company Microwave and Materials Designs has the potential to enable new microwave electroceramic materials to be disc ....Tailoring the microwave dielectric properties of promising electroceramics for use in wireless telecommunication components and devices. This project aims to develop and tailor the microwave dielectric properties of promising electroceramic materials specifically targeting next generation wireless telecommunications applications. The partnership between the ANU and the Australian company Microwave and Materials Designs has the potential to enable new microwave electroceramic materials to be discovered and then incorporated into new microwave components and/or devices developed in response to the requirements of the international wireless telecommunications market. The requested PhD student will gain experience in both the industrial and academic worlds and the skills needed to be part of Australia's high-tech workforce. Read moreRead less
Enabling three dimensional stochastic geological modelling. This project aims to develop technologies to mitigate three dimensional (3D) geological risk in resources management. This project expects to create new knowledge and methods in the field of 3D geological modelling through the innovative application of mathematical methods, structural geology concepts and probabilistic programming. The expected outcomes are an enhanced capability to model the subsurface, characterise model uncertainty a ....Enabling three dimensional stochastic geological modelling. This project aims to develop technologies to mitigate three dimensional (3D) geological risk in resources management. This project expects to create new knowledge and methods in the field of 3D geological modelling through the innovative application of mathematical methods, structural geology concepts and probabilistic programming. The expected outcomes are an enhanced capability to model the subsurface, characterise model uncertainty and test multiple geological scenarios. This enhanced capability is important for the future of Australia's subsurface management, including urban geology and our continuously growing sustainable resources industry.Read moreRead less
Multiscale geomechanical modelling of basin-scale CO2 storage. This project aims to develop innovative geomechanical models that will provide rapid assessments of the potential for reservoir deformation, including induced seismicity, during geological storage of CO2. The main expected outcome is a multiscale modelling approach that will help to identify storage locations at low risk for deformation and CO2 leakage in regions of little existing geomechanical data. The project will elucidate the .... Multiscale geomechanical modelling of basin-scale CO2 storage. This project aims to develop innovative geomechanical models that will provide rapid assessments of the potential for reservoir deformation, including induced seismicity, during geological storage of CO2. The main expected outcome is a multiscale modelling approach that will help to identify storage locations at low risk for deformation and CO2 leakage in regions of little existing geomechanical data. The project will elucidate the technical and commercial viability of CO2 storage in Australia’s Cooper-Eromanga basins and provide broad economic and environmental benefits by reducing the geomechanical uncertainties that provide a barrier to the global need to upscale carbon capture and storage.Read moreRead less