Advanced Imaging For Patient Profiling In Patients With Stroke
Funder
National Health and Medical Research Council
Funding Amount
$319,831.00
Summary
Stroke is the leading cause of adult disability in the developed world. Many patients are require rehabilitation which can vary in terms of its success, and in many cases patients can be left with permanent and significant disability. Approaches to understand the neuroplastic changes associated with poststroke motor impairment are limited. This study aims to further our understanding of stroke recovery by undertaking a longitudinal MRI assessment of patients recovering from stroke.
Acute Stroke Care: Rapid Unblocking Of Vessels, Mending Ruptures, And Recovery
Funder
National Health and Medical Research Council
Funding Amount
$204,399.00
Summary
During this fellowship, A/Prof Meretoja will 1) use blood biomarkers, telemedicine, and ambulance-based imaging to streamline the time-critical therapy of stroke thrombolysis, 2) run a pharmaceutical trial of the drug tranexamic acid in intracerebral haemorrhage, and 3) use stroke registries in Australia and Finland to disseminate best practices in stroke care pathways.
Targeting Peroxisome Proliferator-activated Receptor Gamma As A Novel Therapeutic Strategy Against Cerebrovascular Diseases
Funder
National Health and Medical Research Council
Funding Amount
$335,911.00
Summary
High blood pressure and stroke are major health concerns in Australia. Due to the aging population, the incidence of these diseases is expected to rise. This project aims to identify novel molecules that protect cerebral vessels and the brain against the deleterious effects of high blood pressure and stroke. The identification of such molecules may have implications for the development of new therapies and may result in the delay of dysfunction in the brain and improved overall brain health.
Characterising Motor Network Connectivity To Improve Application Of Non-invasive Brain Stimulation In Stroke
Funder
National Health and Medical Research Council
Funding Amount
$318,768.00
Summary
Stroke is a major health issue and leading cause of disability. Improvements to rehabilitation would be beneficial for both patients and hospital services. Brain stimulation has shown capacity to improve function after stroke. At the moment the effects are highly variable an unable to assist rehabilitation. Strength and pattern of remaining brain connections may explain variable responses to brain stimulation. Tailoring stimulation based on brain function will improve rehabilitation outcomes.
TRIP Fellowship: Bridging The Evidence Practice Gap In Secondary Prevention In Stroke
Funder
National Health and Medical Research Council
Funding Amount
$146,247.00
Summary
Various medications have been shown to reduce the risk of recurrent vascular disease after stroke. This study aims to improve the frequency of use of these medications in patients discharged from hospital after a stroke.
Understanding Stroke Care Health Service Utilisation Beyond The Acute Hospital Setting
Funder
National Health and Medical Research Council
Funding Amount
$316,449.00
Summary
This project will link data from the Australian Stroke Clinical Registry, the stroke survivor and carer needs survey and Commonwealth and state datasets to obtain a better understanding of the post-discharge health service utilisation of survivors of stroke and how this relates to reported long-term unmet needs in this group. This information will be used to inform interventions to improve outcomes and service delivery for survivors of stroke.