Discovery Early Career Researcher Award - Grant ID: DE160100999
Funder
Australian Research Council
Funding Amount
$295,020.00
Summary
Applying forward-backward stochastic differential equations to optimisation. This project intends to develop new ways to solve optimisation problems that are currently difficult to solve because of their complexity and size. In particular, forward–backward stochastic differential equations (FBSDEs) are a new technique that is showing ways to solve problems for which there is yet to be a solution. This project's focus will be on problems that cannot use existing software because the decision-maki ....Applying forward-backward stochastic differential equations to optimisation. This project intends to develop new ways to solve optimisation problems that are currently difficult to solve because of their complexity and size. In particular, forward–backward stochastic differential equations (FBSDEs) are a new technique that is showing ways to solve problems for which there is yet to be a solution. This project's focus will be on problems that cannot use existing software because the decision-making processes require intensive consideration of all possible outcomes in the modelled environment. In comparison to previous optimisation methods, the FBSDE approach is easier to work with and much more informative. The project's main potential applications are multiplayer games with mean-field interaction and financial markets with partial information.Read moreRead less
Early Career Industry Fellowships - Grant ID: IE230100578
Funder
Australian Research Council
Funding Amount
$355,208.00
Summary
Next generation soil carbon satellite-based measurement for carbon markets. Soil carbon sequestration is a federal government priority to offset greenhouse gas emissions. Efforts to advance this opportunity are hindered by the high technical costs of soil carbon quantification. This project will develop an innovative and potentially commercialisable technology that integrates ground data, unmanned aerial vehicles (UAVs), satellites, Eddy covariance CO2 flux towers, soil carbon (C) models, and ar ....Next generation soil carbon satellite-based measurement for carbon markets. Soil carbon sequestration is a federal government priority to offset greenhouse gas emissions. Efforts to advance this opportunity are hindered by the high technical costs of soil carbon quantification. This project will develop an innovative and potentially commercialisable technology that integrates ground data, unmanned aerial vehicles (UAVs), satellites, Eddy covariance CO2 flux towers, soil carbon (C) models, and artificial intelligence (AI) to improve the accuracy of satellite-based soil C modelling. The project will provide an accurate and cost-effective solution to quantification of soil C changes to unlock a large potential of carbon offsets in rangelands in Australia and worldwide.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE200100692
Funder
Australian Research Council
Funding Amount
$417,842.00
Summary
Stopping in the Real World: Cognitive Architectures for Selective Stopping. Response inhibition is the ability to stop actions that are in progress but become no longer appropriate, such as halting an order to launch a missile strike when a civilian vehicle is detected. The project focuses on people’s ability to either stop all planned actions or selectively stop some actions while allowing others to occur. The goal is to develop methodology to reliably measure the time it takes to stop actions, ....Stopping in the Real World: Cognitive Architectures for Selective Stopping. Response inhibition is the ability to stop actions that are in progress but become no longer appropriate, such as halting an order to launch a missile strike when a civilian vehicle is detected. The project focuses on people’s ability to either stop all planned actions or selectively stop some actions while allowing others to occur. The goal is to develop methodology to reliably measure the time it takes to stop actions, investigate the psychological mechanisms involved in stopping, and develop tools for defence-related personnel and job selection. The project provides significant benefits by enabling the study of how response inhibition ensures that appropriate actions occur and how failures of inhibition result in inappropriate actions. Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE160100614
Funder
Australian Research Council
Funding Amount
$363,612.00
Summary
Evolutionary genomics and origin of the molluscan biomineralisation toolkit. The project aims to use new genomes from understudied lineages of Mollusca to identify the genes involved in shell formation (biomineralisation) and infer their function and evolutionary history. The ability of molluscs to biofabricate intricate and robust skeletal structures from sea water is encoded in their genomes. Understanding the ancestral biomineralisation toolkit is of great interest to materials science, which ....Evolutionary genomics and origin of the molluscan biomineralisation toolkit. The project aims to use new genomes from understudied lineages of Mollusca to identify the genes involved in shell formation (biomineralisation) and infer their function and evolutionary history. The ability of molluscs to biofabricate intricate and robust skeletal structures from sea water is encoded in their genomes. Understanding the ancestral biomineralisation toolkit is of great interest to materials science, which seeks to replicate molluscan biomineralisation in vitro for biomedical and other applications. Understanding the toolkit is an important first step toward synthetic biology techniques to 'print' structures like bones in vitro. Moreover, new genomic resources from molluscs will be of interest to researchers in numerous fields.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE240100793
Funder
Australian Research Council
Funding Amount
$463,180.00
Summary
Unraveling a new cytokine working model in immune cell exhaustion. This project will investigate a novel paradigm of how a key messenger protein can be sensed by fundamental immune cells, preventing their ‘exhaustion’. Immune cell exhaustion is a fundamental mechanism to maintain the internal homeostasis of vertebrates. However, it is often hijacked by pathogens to dampen the defensive capacity of the immune system. And this specific messenger protein is the only known soluble factor that can d ....Unraveling a new cytokine working model in immune cell exhaustion. This project will investigate a novel paradigm of how a key messenger protein can be sensed by fundamental immune cells, preventing their ‘exhaustion’. Immune cell exhaustion is a fundamental mechanism to maintain the internal homeostasis of vertebrates. However, it is often hijacked by pathogens to dampen the defensive capacity of the immune system. And this specific messenger protein is the only known soluble factor that can deliver ‘anti-exhaustion’ signals to immune cells. This study will advance basic knowledge in biochemistry and immunology by combining interdisciplinary and cutting-edge approaches. The expected outcomes include the developing new scientific theories and identifying novel molecular basis of biological processes. Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE230100305
Funder
Australian Research Council
Funding Amount
$399,064.00
Summary
Revealing the origin and early evolution of spiralian animal body plans. This project aims to reconstruct the early evolutionary history of the Spiralia, a megadiverse animal group that extends back 540 million years. Their oldest fossils represent some of the earliest known animals and can reveal much about the speed and magnitude of evolution during the Cambrian Explosion, when most animal groups rapidly appeared. This project expects to generate new knowledge on the origin and radiation of so ....Revealing the origin and early evolution of spiralian animal body plans. This project aims to reconstruct the early evolutionary history of the Spiralia, a megadiverse animal group that extends back 540 million years. Their oldest fossils represent some of the earliest known animals and can reveal much about the speed and magnitude of evolution during the Cambrian Explosion, when most animal groups rapidly appeared. This project expects to generate new knowledge on the origin and radiation of some of the first animal body plans to better understand the early history of complex life. Anticipated outcomes and benefits include a new macroevolutionary framework for spiralians, novel approaches to studying invertebrate fossils, and highlighting the scientific importance of Australia’s natural heritage.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE160100293
Funder
Australian Research Council
Funding Amount
$372,000.00
Summary
Cracking the phosphoinositide code. This project seeks to determine how protein interactions with membrane lipids regulate recruitment to cellular organelles, providing new insight into the complex pathways of cellular homeostasis. Controlling the distribution of proteins within cells is critical for cell signalling and membrane trafficking. This is orchestrated by the interaction of specific protein modules with lipids on the surface of different organelles. The phox homology (PX) domain is a l ....Cracking the phosphoinositide code. This project seeks to determine how protein interactions with membrane lipids regulate recruitment to cellular organelles, providing new insight into the complex pathways of cellular homeostasis. Controlling the distribution of proteins within cells is critical for cell signalling and membrane trafficking. This is orchestrated by the interaction of specific protein modules with lipids on the surface of different organelles. The phox homology (PX) domain is a lipid-binding module found in numerous proteins essential for normal cell trafficking and homeostasis, and perturbed in many conditions including immune dysfunction and cancer. This project plans to investigate molecular determinants of PX-lipid association, generating knowledge about protein-membrane interactions required for cellular function. These insights may underpin future drug design.Read moreRead less
Safe and accessible care for older survivors of psychological trauma. This project aims to improve the safety and accessibility of community aged care services for older survivors of psychological trauma, particularly those from diverse populations. We will co-design and test a practice framework that transforms the conceptual principles of trauma-informed care into actionable care behaviours and processes for implementation. Outcomes will include a world-first roadmap to guide implementation of ....Safe and accessible care for older survivors of psychological trauma. This project aims to improve the safety and accessibility of community aged care services for older survivors of psychological trauma, particularly those from diverse populations. We will co-design and test a practice framework that transforms the conceptual principles of trauma-informed care into actionable care behaviours and processes for implementation. Outcomes will include a world-first roadmap to guide implementation of trauma-informed aged care, as well for policy makers to regulate and monitor its delivery. The project will also increase knowledge about the priorities for change within aged care from the perspective of older trauma survivors, and improve understanding of how best to engage this group in co-design.Read moreRead less
A Method for Analysis of Complexity in Cognitive Processes: Applications to Prediction of Industrial Workloads. The project will develop a method for analysis of cognitive complexity in human and animal cognition. It will contribute to basic research because it will enable equivalences and relative complexities of cognitive functions to be determined, independent of content or methodology. It will have applications to education, because it enables complexities of concepts to be recognised and a ....A Method for Analysis of Complexity in Cognitive Processes: Applications to Prediction of Industrial Workloads. The project will develop a method for analysis of cognitive complexity in human and animal cognition. It will contribute to basic research because it will enable equivalences and relative complexities of cognitive functions to be determined, independent of content or methodology. It will have applications to education, because it enables complexities of concepts to be recognised and appropriate pedagogies determined. It also has application to human factors, especially industrial performance and decision making. It will advance on currrent methods because it enables workload to be analysed and predicted, so that it can be factored into job and system design. Read moreRead less
Speech perception precedes, indexes, and is changed by language acquisition. What is exceptional about human infants is not their sophisticated speech perception (for animals perceive human speech similarly) but their use of speech to regulate linguistic attention and bootstrap language. Using a new validated measure, language specific speech perception (discrimination ability for native minus non-native speech sounds), we can ascertain children's distribution of resources in linguistic tasks. T ....Speech perception precedes, indexes, and is changed by language acquisition. What is exceptional about human infants is not their sophisticated speech perception (for animals perceive human speech similarly) but their use of speech to regulate linguistic attention and bootstrap language. Using a new validated measure, language specific speech perception (discrimination ability for native minus non-native speech sounds), we can ascertain children's distribution of resources in linguistic tasks. This measure will be used in conjunction with a raft of experimental psycholinguistic techniques to investigate speech perception bases of phoneme perception, tone perception, word meaning, reading, and their vestiges in adulthood, to arrive at a dynamic new conception of language development. Read moreRead less