An anti-senescence nanoplatform and its underlying mechanism. The project will bring together complementary expertise and skills by combining biomaterials, cell and molecular biology, and engineering, to develop a novel nano-biomaterial platform for anti-senescence and gain an in-depth understanding of its underlying mechanisms. The underlying mechanisms of senescence remain elusive and bone substitutes with anti-senescence property have not been explored and becoming a growing field of interest ....An anti-senescence nanoplatform and its underlying mechanism. The project will bring together complementary expertise and skills by combining biomaterials, cell and molecular biology, and engineering, to develop a novel nano-biomaterial platform for anti-senescence and gain an in-depth understanding of its underlying mechanisms. The underlying mechanisms of senescence remain elusive and bone substitutes with anti-senescence property have not been explored and becoming a growing field of interest in bone regeneration. The project will develop a well-defined and efficient nanomaterial platform with optimal combination of nano-surface features and chemistry for cell rejuvenation, and it will give unprecedented depth of interdisciplinary understanding of senescence rejuvenation mechanisms.Read moreRead less
The role of protein glycosylation in erythropoiesis . This project aims to understand how the sugar code of key-signalling proteins influences the development of red blood cells. This project expects to generate new fundamental knowledge in the area of stem cell signalling by innovative integration of biological and computational molecular characterisation techniques. The expected outcomes of this project include the development of novel workflows to study key regulators of cell development and ....The role of protein glycosylation in erythropoiesis . This project aims to understand how the sugar code of key-signalling proteins influences the development of red blood cells. This project expects to generate new fundamental knowledge in the area of stem cell signalling by innovative integration of biological and computational molecular characterisation techniques. The expected outcomes of this project include the development of novel workflows to study key regulators of cell development and the generation of new knowledge in stem cell signalling that will find applications in transforming stem cell therapies and associated research for future applications such as the laboratory manufacturing of red blood cells to close the availability gap for transfusion purposes.Read moreRead less
Tuning mesenchymal stem cell lifespan, performance, and differentiation. This project aims to fully characterise a unique molecular process that strongly modulates mesenchymal stem cell lifespan and behaviour. This work is significant, as it is expected to reveal new concepts underpinning the mechanistic actions of classical structural proteins. It will also shape a more nuanced understanding of the context-dependent mechanical and biochemical signals that regulate stem cell fate and function. E ....Tuning mesenchymal stem cell lifespan, performance, and differentiation. This project aims to fully characterise a unique molecular process that strongly modulates mesenchymal stem cell lifespan and behaviour. This work is significant, as it is expected to reveal new concepts underpinning the mechanistic actions of classical structural proteins. It will also shape a more nuanced understanding of the context-dependent mechanical and biochemical signals that regulate stem cell fate and function. Expected outcomes include new knowledge surrounding native extracellular matrix and stem cell biology, and the development of strategies to define and tailor stem cell properties. This work is anticipated to drive new technologies that can efficiently and robustly manipulate stem cells for diverse functional applications.Read moreRead less
Degradation of atomically dispersed M-N-C carbon catalysts in acidic media. This project aims to provide a clear understanding of the degradation mechanisms of transition metal (M) and nitrogen (N) co-doped carbon (M-N-C) catalysts in acidic media by utilising new model catalysts, standardised degradation tests, comprehensive catalyst characterisation, and machine learning tools to interrogate mechanistic hypotheses and link degradation mechanisms to specific catalyst characteristics. This proje ....Degradation of atomically dispersed M-N-C carbon catalysts in acidic media. This project aims to provide a clear understanding of the degradation mechanisms of transition metal (M) and nitrogen (N) co-doped carbon (M-N-C) catalysts in acidic media by utilising new model catalysts, standardised degradation tests, comprehensive catalyst characterisation, and machine learning tools to interrogate mechanistic hypotheses and link degradation mechanisms to specific catalyst characteristics. This project expects to generate new knowledge on rationally designing robust hydrogen fuel cell catalysts. This will provide significant benefits, such as new knowledge on catalyst degradation, new catalysts for energy conversion applications, and collaborations with the industry to accelerate Australia’s shift to renewable energy.Read moreRead less
Hot carrier cooling mechanisms in nano structures. This project aims to systematically investigate possible mechanisms of hot carrier cooling in nano structures and to identify the most dominant mechanisms. These are important for efficient hot carrier solar cells and thermoelectrics. This project will develop new physics to understand hot carrier dynamics in nano structures. This project is expected to result in photovoltaic systems with a lower balance of system and levelised cost of electrici ....Hot carrier cooling mechanisms in nano structures. This project aims to systematically investigate possible mechanisms of hot carrier cooling in nano structures and to identify the most dominant mechanisms. These are important for efficient hot carrier solar cells and thermoelectrics. This project will develop new physics to understand hot carrier dynamics in nano structures. This project is expected to result in photovoltaic systems with a lower balance of system and levelised cost of electricity compared to conventional technologies. This should boost solar industry, create green jobs and reduce greenhouse gas emissions.Read moreRead less
Enabling technology unlocking full potential of high bandgap chalcopyrite . This project is aimed at solving the fundamental challenges of high bandgap chalcopyrite light-harvesting material to unlock its full potential as the top cell for photovoltaic tandem cell and the photocathode for photoelectrochemical applications. This will be realised by dynamic optimisation of its performance in photovoltaic solar cell device through understanding of its defects origins, enabling defects controlling t ....Enabling technology unlocking full potential of high bandgap chalcopyrite . This project is aimed at solving the fundamental challenges of high bandgap chalcopyrite light-harvesting material to unlock its full potential as the top cell for photovoltaic tandem cell and the photocathode for photoelectrochemical applications. This will be realised by dynamic optimisation of its performance in photovoltaic solar cell device through understanding of its defects origins, enabling defects controlling technologies, and microscopic carrier loss mechanism analysis via systematic macro-to-micro characterisations combined with 3D device simulation. The project completion will reinforce the next-generation tandem cell and photoelectrochemical technologies with the efficient, stable, RoHS-compliant and thin chalcopyrite devices.Read moreRead less
Nitride materials: In the “bond ionicity Goldilocks zone” for solar energy. Progress towards commercial devices for solar-driven hydrogen generation as well as in-situ electricity generation for vehicles is currently hampered by a lack of earth-abundant, stable, non-toxic semiconductor materials that can be fabricated by scalable methods. This project aims to develop the first scalable solution synthesis methods for a new class of earth-abundant Zn-based nitride semiconductor nanocrystals that h ....Nitride materials: In the “bond ionicity Goldilocks zone” for solar energy. Progress towards commercial devices for solar-driven hydrogen generation as well as in-situ electricity generation for vehicles is currently hampered by a lack of earth-abundant, stable, non-toxic semiconductor materials that can be fabricated by scalable methods. This project aims to develop the first scalable solution synthesis methods for a new class of earth-abundant Zn-based nitride semiconductor nanocrystals that have favourable bond ionicity and establish their optoelectronic properties for renewable energy devices for the first time. Flexible solution processing methods will be exploited to tune surface composition, remove defects and create devices to achieve optimised performance in these challenging new nitride material systems.Read moreRead less
Corrosion of heat resisting alloys in steam/hydrogen-rich environment . Hydrogen is a clean fuel for energy future. Its production and utilisation unavoidably involve water vapour and hydrogen at high temperature which is however corrosive to materials used in the system. This project aims to investigate corrosion behaviour of heat resistant alloys in the presence of both hydrogen and water vapour, mechanisms of water transport in oxide scale, and the effect of hydrogen on water vapour corrosion ....Corrosion of heat resisting alloys in steam/hydrogen-rich environment . Hydrogen is a clean fuel for energy future. Its production and utilisation unavoidably involve water vapour and hydrogen at high temperature which is however corrosive to materials used in the system. This project aims to investigate corrosion behaviour of heat resistant alloys in the presence of both hydrogen and water vapour, mechanisms of water transport in oxide scale, and the effect of hydrogen on water vapour corrosion. Alloying effects on corrosion rates will be defined and methods of slowing or preventing water vapour corrosion in the presence of hydrogen will be devised. The results will provide a basis for improved design/selection of heat resisting alloys for hydrogen production and hydrogen utilisation industries.Read moreRead less
Advanced electrocatalysts for ammonia synthesis with validated analysis. Ammonia is one of the most produced chemicals worldwide but current manufacturing industries consume massive amounts of energy and emit harmful greenhouse gases. This project aims to develop a sustainable electrochemical system for ammonia synthesis using electricity and atmospheric nitrogen. A family of porous catalysts with nanoconfined ionic liquids will be developed to drive nitrogen reduction by enhancing the reaction ....Advanced electrocatalysts for ammonia synthesis with validated analysis. Ammonia is one of the most produced chemicals worldwide but current manufacturing industries consume massive amounts of energy and emit harmful greenhouse gases. This project aims to develop a sustainable electrochemical system for ammonia synthesis using electricity and atmospheric nitrogen. A family of porous catalysts with nanoconfined ionic liquids will be developed to drive nitrogen reduction by enhancing the reaction kinetics. Rigorous experimental protocols and novel analytical methods will be developed for quantification of electro-synthesised ammonia. A prototype gas diffusion layer-assisted electrolyser will be demonstrated by coupling with oxygen evolution reactions for selective ammonia synthesis at a reasonable production rate.Read moreRead less
Efficient photovoltaic-electrochemical water splitting for clean hydrogen. This project aims to develop a novel, low cost and high performance monolithic photovoltaic-electrochemical (PV-EC) device for clean hydrogen production. This device tailors and integrates low cost and high performance thin film and tandem photovoltaics for water splitting with the aim of achieving high solar to hydrogen conversion efficiency towards 20%. Earth abundant and stable catalysts will be developed in this proje ....Efficient photovoltaic-electrochemical water splitting for clean hydrogen. This project aims to develop a novel, low cost and high performance monolithic photovoltaic-electrochemical (PV-EC) device for clean hydrogen production. This device tailors and integrates low cost and high performance thin film and tandem photovoltaics for water splitting with the aim of achieving high solar to hydrogen conversion efficiency towards 20%. Earth abundant and stable catalysts will be developed in this project to replace noble based catalysts, as well as novel architectures for electrical contacting, feed-through and catalyst integration in PV-EC devices. These innovations offer high performance and the potential for device costs 2 to 3 orders of magnitude lower than recent world record photoelectrochemical devices. Read moreRead less