Bayesian Inference for Multivariate Hierarchical Regression Models. This project will develop Bayesian methodology for analysing multivariate regression models. The distribution of each measurement can be discrete or continuous, with the dependence between measurements obtained through the correlation matrix of a Gaussian copula. Model parsimony is obtained by identifying zero elements in the correlation matrix or its inverse and by variable selection on the regression parameters. The results wi ....Bayesian Inference for Multivariate Hierarchical Regression Models. This project will develop Bayesian methodology for analysing multivariate regression models. The distribution of each measurement can be discrete or continuous, with the dependence between measurements obtained through the correlation matrix of a Gaussian copula. Model parsimony is obtained by identifying zero elements in the correlation matrix or its inverse and by variable selection on the regression parameters. The results will be applied to solve problems in finance, health management and marketing. In all these fields multiple observations are often taken per individual or time period and the models need to incorporate measures of dependence and uncertainty.Read moreRead less
Statistical Methods for Flow Cytometric Data. The project will aid users of flow cytometry throughout Australia. It will help foster collaborations between the biological and mathematical scientists. Biological research is an important part of Australia's future and is becoming very quantitative. During the course of the project, two PhD students will be provided strong training in Statistics geared towards biological applications. The project is aligned with the 8th Human Leucocyte Differentiat ....Statistical Methods for Flow Cytometric Data. The project will aid users of flow cytometry throughout Australia. It will help foster collaborations between the biological and mathematical scientists. Biological research is an important part of Australia's future and is becoming very quantitative. During the course of the project, two PhD students will be provided strong training in Statistics geared towards biological applications. The project is aligned with the 8th Human Leucocyte Differentiation Antigen workshop to culminate in Adelaide in December 2004 and will aid the fight against blood cell cancers. The project will also aid research on plankton with potential commercial benefits for Australia's marine scallop industry.
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Bayesian inference for complex regression models using mixtures. The project will use mixtures to flexibly model complex regression functions and will develop Bayesian methods for carrying out statistical inference on these models. The models will deal with both Gaussian and non-Gaussian data. Multiple explanatory variables are dealt with by mixing simple additives to produce flexible high dimensional function estimates. Variable selection and model averaging will be used to identify important v ....Bayesian inference for complex regression models using mixtures. The project will use mixtures to flexibly model complex regression functions and will develop Bayesian methods for carrying out statistical inference on these models. The models will deal with both Gaussian and non-Gaussian data. Multiple explanatory variables are dealt with by mixing simple additives to produce flexible high dimensional function estimates. Variable selection and model averaging will be used to identify important variables and thus make the estimation more efficient. The methods will be extended to multivariate responses where account will taken be taken of the structure of the dependence between responses.Read moreRead less
Increasing the effectiveness of quantitative verification. The ability to analyse the performance of complex systems and protocols is a vital part of the development of large-scale computer applications. Methods that improve the effectiveness of the analysis task would increase the competitiveness of the software industry, and would attract future development work (in complex systems) to Australia. The results of this project will have a direct influence on currently available design tools; the ....Increasing the effectiveness of quantitative verification. The ability to analyse the performance of complex systems and protocols is a vital part of the development of large-scale computer applications. Methods that improve the effectiveness of the analysis task would increase the competitiveness of the software industry, and would attract future development work (in complex systems) to Australia. The results of this project will have a direct influence on currently available design tools; the fact that Australian institutions will be (in part) responsible for key theoretical results in this growing field will strengthen Australia's position worldwide as an international centre for computer science.Read moreRead less
A New Approach to Air Traffic Management to Deliver Significantly Reduced Environmental Impact and System-wide Efficiencies. Aviation is often cited as a major contributor to harmful emissions in the upper atmosphere. The primary outcome of this project is the development of tools that will enable aviation industry stakeholders to optimise the deployment of 4-Dimensional User Preferred Trajectories across Australian airspace. It is expected that this will result in significant environmental bene ....A New Approach to Air Traffic Management to Deliver Significantly Reduced Environmental Impact and System-wide Efficiencies. Aviation is often cited as a major contributor to harmful emissions in the upper atmosphere. The primary outcome of this project is the development of tools that will enable aviation industry stakeholders to optimise the deployment of 4-Dimensional User Preferred Trajectories across Australian airspace. It is expected that this will result in significant environmental benefit, through reductions in fuel burn for each flight, and increases in system effectiveness. The project will enable better analysis of Australian aviation environmental effect, whilst at the same time allowing the aviation industry to continue to contribute to Australia's sustainable economic growth. Read moreRead less
Nano-Rheology and Nano-Tribology: Atomistic Simulation of Boundary Lubrication. Manufacturing in atomic level is going to transform the efficiency level in many important applications. As molecular biology transformed medical and biological sciences,so molecular level material design and the techniques involved are going to significantly affect the engineering applications and manufacturing in coming decades. We have no doubt the benefits will flow from the project to many disciplines that are c ....Nano-Rheology and Nano-Tribology: Atomistic Simulation of Boundary Lubrication. Manufacturing in atomic level is going to transform the efficiency level in many important applications. As molecular biology transformed medical and biological sciences,so molecular level material design and the techniques involved are going to significantly affect the engineering applications and manufacturing in coming decades. We have no doubt the benefits will flow from the project to many disciplines that are critical in manufacturing and commercialisation of nano-devices. The results will position Australia in the forefront of one of the most important leading edge technologies in the world. This not only will improve Australia's research profile in the world but also will enable it to capitalize on any future commercial outcomesRead moreRead less
Novel time-frequency techniques for analysing and modeling non-stationary physical and engineering data. This project addresses an issue of fundamental importance in science and technology, where non-stationary data (which have time-varying statistics) are ubiquitous. Therefore, the development of time-frequency tools to model and analyse non-stationary data has great potential for impact in a wide range of areas reaching from seismic data analysis to biomedical signal processing to sonar and ra ....Novel time-frequency techniques for analysing and modeling non-stationary physical and engineering data. This project addresses an issue of fundamental importance in science and technology, where non-stationary data (which have time-varying statistics) are ubiquitous. Therefore, the development of time-frequency tools to model and analyse non-stationary data has great potential for impact in a wide range of areas reaching from seismic data analysis to biomedical signal processing to sonar and radar. Employing techniques to be developed in this proposal, we expect to be able to classify and detect features of non-stationary data that were unrecognisable using hitherto known methods.Read moreRead less
ARC Centre in Bioinformatics. The Australian Centre for Genome-Phenome Bioinformatics will examine how the genome comes to life in the mammalian cell during differentiation and development. We will model, visualise and experimentally validate the complex cellular systems and regulatory networks that control the transformation of genomic information into biological structure and function. We will develop novel approaches and tools to improve health, optimise agricultural production and exploit ne ....ARC Centre in Bioinformatics. The Australian Centre for Genome-Phenome Bioinformatics will examine how the genome comes to life in the mammalian cell during differentiation and development. We will model, visualise and experimentally validate the complex cellular systems and regulatory networks that control the transformation of genomic information into biological structure and function. We will develop novel approaches and tools to improve health, optimise agricultural production and exploit new cell technologies. The Centre will build critical mass and national focus in bioinformatics to generate the human capital and intellectual property that Australia needs to compete in advanced bioscience and biotechnology.Read moreRead less
Micromechanical modelling of fault gouge dynamics: towards an improved fault constitutive relation. The human and economic costs of geological and other particulate media related problems in Australia are staggering. These include geological hazards (e.g. landslides and earthquakes; the Newcastle earthquake cost around $4 billion and 13 lives), to particulate processes prevalent in Australia's major export industries (e.g. coal export valued at $9.3 billion, iron ore at $3.8 billion, and wheat ....Micromechanical modelling of fault gouge dynamics: towards an improved fault constitutive relation. The human and economic costs of geological and other particulate media related problems in Australia are staggering. These include geological hazards (e.g. landslides and earthquakes; the Newcastle earthquake cost around $4 billion and 13 lives), to particulate processes prevalent in Australia's major export industries (e.g. coal export valued at $9.3 billion, iron ore at $3.8 billion, and wheat at $3.4 billion), to Australia's 810,000 km granular paved road network that costs around $5.5 million per day to maintain. The program will deliver new knowledge and advanced analytical and predictive modelling tools capable of fuelling breakthroughs in earthquake forecasting research and industrial innovations.
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Simulating the evolution of the Southern Ocean and Australia's Palaeo-environment over 40 million years. Our project falls in the first national research priority: an environmentally sustainable Australia and meets two of its primary goals, understanding environmental change and the evolution of biodiversity, and responding to climate change and variability. Our models will represent a major step forward in differentiating between natural processes and anthropological input to present global cli ....Simulating the evolution of the Southern Ocean and Australia's Palaeo-environment over 40 million years. Our project falls in the first national research priority: an environmentally sustainable Australia and meets two of its primary goals, understanding environmental change and the evolution of biodiversity, and responding to climate change and variability. Our models will represent a major step forward in differentiating between natural processes and anthropological input to present global climate change and will address quantitatively how Australia changed from a continent rich in freshwater to the driest inhabited continent throughout the last 40 million years.Read moreRead less