Predicting the value and use of urban land. This project aims to develop a comprehensive, robust and user-friendly set of modelling tools to predict land values more accurately. Accurate predictions of land values reduce state government revenue risks and improve resource management. The expected outcome of this project is the development of modelling tools which, can be used to study land use allocation, infrastructure delivery and government taxation revenue. This should provide significant be ....Predicting the value and use of urban land. This project aims to develop a comprehensive, robust and user-friendly set of modelling tools to predict land values more accurately. Accurate predictions of land values reduce state government revenue risks and improve resource management. The expected outcome of this project is the development of modelling tools which, can be used to study land use allocation, infrastructure delivery and government taxation revenue. This should provide significant benefits such as the development of new econometric theory, advanced computational methods and evidence-based guidelines for policymakers.Read moreRead less
Statistical methods for quantifying variation in spatiotemporal areal data. This project aims to develop new statistical methods for extracting insights into spatial and temporal variation in areal data. These tools will extend the Australian Cancer Atlas which provides small area estimates for 20 cancers across Australia. The project is significant because it will allow government and other organisations to reap dividends from investment in collecting spatial information and it will enable mode ....Statistical methods for quantifying variation in spatiotemporal areal data. This project aims to develop new statistical methods for extracting insights into spatial and temporal variation in areal data. These tools will extend the Australian Cancer Atlas which provides small area estimates for 20 cancers across Australia. The project is significant because it will allow government and other organisations to reap dividends from investment in collecting spatial information and it will enable modelled small-area estimates to be released without compromising confidentiality. The expected outcomes include new statistical knowledge and new insights into cancer. The results will benefit the many disciplines, managers and policy makers that make decisions based on geographic data mapped over space and time. Read moreRead less
Artificial intelligence to explore and combat eukaryotic pathogens. The revolution in artificial intelligence (AI) provides unprecedented opportunities for integrative analyses of complex multi-omics data sets and for creating radically new strategies to control some of the world’s most serious animal diseases. In a strong partnership with international experts, we will use AI-based methods to make major conceptual advances in our understanding of eukaryotic pathogens and host-pathogen interacti ....Artificial intelligence to explore and combat eukaryotic pathogens. The revolution in artificial intelligence (AI) provides unprecedented opportunities for integrative analyses of complex multi-omics data sets and for creating radically new strategies to control some of the world’s most serious animal diseases. In a strong partnership with international experts, we will use AI-based methods to make major conceptual advances in our understanding of eukaryotic pathogens and host-pathogen interactions, discover the "choke-points" in biological pathways, and develop novel treatments, vaccines and diagnostics. This leap forward will substantially enhance the global profile of pathogen research in Australia, build major capacity in a priority area, and enable access to international research funding and networks.Read moreRead less
Borderline Personality as Social Phenomena. Mental disorders attract social stigma and those diagnosed are widely misunderstood. This project aims to collect and analyse accounts of people living with Borderline Personality Disorder (BPD) - mainly women - and perspectives of social support practitioners. The intended outcome is to provide a sophisticated understanding of BPD as a social phenomenon, develop sociological evidence based on lived experiences and generate Australian digital resources ....Borderline Personality as Social Phenomena. Mental disorders attract social stigma and those diagnosed are widely misunderstood. This project aims to collect and analyse accounts of people living with Borderline Personality Disorder (BPD) - mainly women - and perspectives of social support practitioners. The intended outcome is to provide a sophisticated understanding of BPD as a social phenomenon, develop sociological evidence based on lived experiences and generate Australian digital resources including narratives of BPD, creative outputs and practitioner perspectives. The anticipated goal of this project is to inform policy and community responses addressing stigma and marginalisation, and the improvement of social support for those affected by BPD.Read moreRead less
Gaining insights into mine waste dumps to avoid environmental legacies. The project aims to develop new methods for identifying pollution source hotspots and pathways inside mine waste rock dumps. This addresses the national need for effective management of Acid and Metalliferous Drainage (AMD), which is now a critical consideration in the viability of new mines and in confronting pollution legacies of old mines. The research will develop and test innovative methods of geophysical and geochemica ....Gaining insights into mine waste dumps to avoid environmental legacies. The project aims to develop new methods for identifying pollution source hotspots and pathways inside mine waste rock dumps. This addresses the national need for effective management of Acid and Metalliferous Drainage (AMD), which is now a critical consideration in the viability of new mines and in confronting pollution legacies of old mines. The research will develop and test innovative methods of geophysical and geochemical analysis and their integration that provide 3-dimensional mapping of key physical and chemical features of the dump. Expected outcomes include greater confidence in the ability of the mining industry to manage its AMD liability. Read moreRead less
Play about Place: Expanding the impact of Creative Placemaking after COVID. This project aims to establish a new approach to placemaking through the development of urban play projects. The project expects to generate affordable and engaging experiences that activate existing public spaces, a typology and methodology for analysing the impacts of urban play, and a comparative study of urban play in Melbourne and Christchurch. Expected outcomes include creative placemaking strategies and projects, ....Play about Place: Expanding the impact of Creative Placemaking after COVID. This project aims to establish a new approach to placemaking through the development of urban play projects. The project expects to generate affordable and engaging experiences that activate existing public spaces, a typology and methodology for analysing the impacts of urban play, and a comparative study of urban play in Melbourne and Christchurch. Expected outcomes include creative placemaking strategies and projects, a connected impact study, and an industry resource for local government outlining our approach. This should provide significant benefits, including First Peoples storytelling experiences, city activation post-pandemic, community engagement, the potential to create jobs and provide economic and social benefit for Australia.Read moreRead less
Protein biosensors for detecting smoke exposure of grapes. Bush fires and controlled burns that take place in the vicinity of vineyards can lead to grape contamination with tasteless phenolic glucosides. Their hydrolysis during wine making leads to “smoke taint” – an unpleasant medicinal taste that can render wine undrinkable. We will apply a combination of organic synthesis, protein engineering and directed evolution to develop protein-based biosensors of phenolic glucosides. These biosensors w ....Protein biosensors for detecting smoke exposure of grapes. Bush fires and controlled burns that take place in the vicinity of vineyards can lead to grape contamination with tasteless phenolic glucosides. Their hydrolysis during wine making leads to “smoke taint” – an unpleasant medicinal taste that can render wine undrinkable. We will apply a combination of organic synthesis, protein engineering and directed evolution to develop protein-based biosensors of phenolic glucosides. These biosensors will be used to devise a simple portable colorimetric test that can be performed in the vineyard or the winery. The ability to rapidly determine the level of grape contamination with phenolic glucosides would give Australian wine growers and wine makers a powerful tool to mitigate the effects of bushfires.Read moreRead less
Integrative brain imaging technologies. This project aims to develop quantitative metabolic imaging using simultaneous magnetic resonance imaging (MRI) and positron emission tomography (PET). The current generation of MR-PET scanners are capable of simultaneously acquiring MRI and PET data to enable quantitative anatomical, physiological and metabolic imaging. The project aims to develop new MRI methods for quantitative anatomical mapping, MR-based motion correction of dynamic PET scan data, and ....Integrative brain imaging technologies. This project aims to develop quantitative metabolic imaging using simultaneous magnetic resonance imaging (MRI) and positron emission tomography (PET). The current generation of MR-PET scanners are capable of simultaneously acquiring MRI and PET data to enable quantitative anatomical, physiological and metabolic imaging. The project aims to develop new MRI methods for quantitative anatomical mapping, MR-based motion correction of dynamic PET scan data, and joint estimation of physiological and metabolic organ activity. These advances will create innovative imaging technologies for advanced biomedical imaging research with a particular emphasis in healthy ageing.
Read moreRead less
Re-conceptualising services from the perspectives of young people. This project aims to contribute the perspectives and voices of vulnerable young people to debates on the need for service reform. It will actively engage children and teens who have complex support needs in service re-design and decision making, and will trial child-led service initiatives. It will also explore organisational barriers to including young people in policy debate and service decision-making. Expected outcomes includ ....Re-conceptualising services from the perspectives of young people. This project aims to contribute the perspectives and voices of vulnerable young people to debates on the need for service reform. It will actively engage children and teens who have complex support needs in service re-design and decision making, and will trial child-led service initiatives. It will also explore organisational barriers to including young people in policy debate and service decision-making. Expected outcomes include increased knowledge of how to effectively engage young people, and understanding of the impact of their participation both for young people and for services. Read moreRead less