Milk protein profiling powered by multiplexed single molecule assay. This project aims to develop a novel device, comprising advanced single molecule imaging, microfluidics and immunoassay technologies, for quantification of milk protein variants. Milk quality is central to dairying and variants of proteins in milk affect its market value. No current milk protein detection technologies are readily applied in milk production quality control. This project aims to produce a device that can be used ....Milk protein profiling powered by multiplexed single molecule assay. This project aims to develop a novel device, comprising advanced single molecule imaging, microfluidics and immunoassay technologies, for quantification of milk protein variants. Milk quality is central to dairying and variants of proteins in milk affect its market value. No current milk protein detection technologies are readily applied in milk production quality control. This project aims to produce a device that can be used by milk producers and farms to profile protein variants with high sensitivity in a single test in an hour and screen unwanted protein contamination. The platform also has great potential for detecting other complex and low content analytes. It builds on innovations in nanoparticles and recent industry collaboration.Read moreRead less
Targeting conjugated markers with new metabolomic methods. Detecting the illicit use of natural steroids like testosterone, or compounds that modulate natural steroid levels, remains the greatest challenge for drug testing in all forms of sport. This project aims to develop new metabolomic methods based on liquid chromatography-high resolution mass spectrometry to detect the changes occurring in the conjugated steroid profile following the administration of steroids or steroid modulators. The in ....Targeting conjugated markers with new metabolomic methods. Detecting the illicit use of natural steroids like testosterone, or compounds that modulate natural steroid levels, remains the greatest challenge for drug testing in all forms of sport. This project aims to develop new metabolomic methods based on liquid chromatography-high resolution mass spectrometry to detect the changes occurring in the conjugated steroid profile following the administration of steroids or steroid modulators. The intended outcome will be a set of sensitive and analytical methods using a range of newly identified conjugated steroid markers and associated reference materials, which promises to enhance integrity and animal welfare in the thoroughbred racing industry.
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Bioinks that Advance 3D bioprinting of cells to the 4th dimension. The aim of this research is to provide a simple method for creating complex 3D cell cultures for in vitro cell based assays using 3D printing. A versatile polymer system as a bioink made from entirely commercially available components, will be advanced that gives a full range of soft tissue mimics and which can be dynamically change on-demand after printing of the 3D cell cultures. The latter will provide in vitro mimics of in vi ....Bioinks that Advance 3D bioprinting of cells to the 4th dimension. The aim of this research is to provide a simple method for creating complex 3D cell cultures for in vitro cell based assays using 3D printing. A versatile polymer system as a bioink made from entirely commercially available components, will be advanced that gives a full range of soft tissue mimics and which can be dynamically change on-demand after printing of the 3D cell cultures. The latter will provide in vitro mimics of in vivo events never previously possible with more realistic models of what is found in vivo. Applications are in fundamental cell biology, studying diseases and developing new drugs. The outcomes from this research will be new knowledge on designing cheap extracellular matrix mimics and high throughout 3D cell assays.Read moreRead less
Thermodynamics inversion for mineral systems. This project aims to provide a newly developed science approach to the Australian Lithospheric Architecture Magnetotelluric Project (AusLAMP). AusLAMP provides unparalleled geophysical information aimed at unravelling the tectonic history of the Australian continent and its mineral potential. The project will use thermodynamically based geodynamic simulators to jointly analyse and quantify intraplate deformation. This will illuminate the cause of dri ....Thermodynamics inversion for mineral systems. This project aims to provide a newly developed science approach to the Australian Lithospheric Architecture Magnetotelluric Project (AusLAMP). AusLAMP provides unparalleled geophysical information aimed at unravelling the tectonic history of the Australian continent and its mineral potential. The project will use thermodynamically based geodynamic simulators to jointly analyse and quantify intraplate deformation. This will illuminate the cause of driving fluid flow thorough the lithosphere, mineralisation phenomena, their datasets and geometries, and dynamic aspects of the processes driving mineral systems.Read moreRead less
Terahertz lasers in the fight against illicit substances. This project aims to investigate the application of cutting-edge terahertz laser technology with new spectroscopic methods, for detection of illicit substances. Using a collaborative approach, the project aims to bring together expertise in laser physics, spectroscopy, law enforcement and instrumentation, and seeks to develop new sources and detection protocols which will offer new capabilities to law enforcement, aiding in detection and ....Terahertz lasers in the fight against illicit substances. This project aims to investigate the application of cutting-edge terahertz laser technology with new spectroscopic methods, for detection of illicit substances. Using a collaborative approach, the project aims to bring together expertise in laser physics, spectroscopy, law enforcement and instrumentation, and seeks to develop new sources and detection protocols which will offer new capabilities to law enforcement, aiding in detection and identification protocols for illicit substances.Read moreRead less
Borderline Personality as Social Phenomena. Mental disorders attract social stigma and those diagnosed are widely misunderstood. This project aims to collect and analyse accounts of people living with Borderline Personality Disorder (BPD) - mainly women - and perspectives of social support practitioners. The intended outcome is to provide a sophisticated understanding of BPD as a social phenomenon, develop sociological evidence based on lived experiences and generate Australian digital resources ....Borderline Personality as Social Phenomena. Mental disorders attract social stigma and those diagnosed are widely misunderstood. This project aims to collect and analyse accounts of people living with Borderline Personality Disorder (BPD) - mainly women - and perspectives of social support practitioners. The intended outcome is to provide a sophisticated understanding of BPD as a social phenomenon, develop sociological evidence based on lived experiences and generate Australian digital resources including narratives of BPD, creative outputs and practitioner perspectives. The anticipated goal of this project is to inform policy and community responses addressing stigma and marginalisation, and the improvement of social support for those affected by BPD.Read moreRead less
High performance, optimized chip-scale packaging for millimetre wave and THz integrated circuits. This project aims to revolutionise electronic packaging by depositing a thin, protective layer of diamond on top of high-performance, millimetre-wave and THz integrated circuits. Leveraging existing technology for removing heat from high-powered optical electronics, the project aims to deliver a miniaturised packaged chip, protected from the environment and ready for mounting in a system, without se ....High performance, optimized chip-scale packaging for millimetre wave and THz integrated circuits. This project aims to revolutionise electronic packaging by depositing a thin, protective layer of diamond on top of high-performance, millimetre-wave and THz integrated circuits. Leveraging existing technology for removing heat from high-powered optical electronics, the project aims to deliver a miniaturised packaged chip, protected from the environment and ready for mounting in a system, without seriously degrading the circuit's performance as occurs in current packaging technologies. The project aims to enable cheaper and more energy-efficient applications as wide ranging as wireless HD video, multi-gigabit telecommunications, and black-body passive imaging technologies for security, defence, medical and agricultural applications.Read moreRead less
Thermal Optimisation of Gigascale Solar Photovoltaics. Large-scale solar photovoltaics are critical to decarbonising the global economy. Sun Cable is developing the world’s largest solar farm in the Northern Territory, and is considering deploying the 5B MAV solar array. At this scale, temperature-induced panel efficiency losses represent a major challenge that must be overcome through thermal performance optimisation. We will build sophisticated multiscale models to simulate and understand the ....Thermal Optimisation of Gigascale Solar Photovoltaics. Large-scale solar photovoltaics are critical to decarbonising the global economy. Sun Cable is developing the world’s largest solar farm in the Northern Territory, and is considering deploying the 5B MAV solar array. At this scale, temperature-induced panel efficiency losses represent a major challenge that must be overcome through thermal performance optimisation. We will build sophisticated multiscale models to simulate and understand the multiple interacting phenomena that cause panel heating, for the first time. This project will create the tools and know-how to optimise array design and solar farm development, delivering major efficiency gains and enhancing the viability of future gigascale solar projects.Read moreRead less
Re-conceptualising services from the perspectives of young people. This project aims to contribute the perspectives and voices of vulnerable young people to debates on the need for service reform. It will actively engage children and teens who have complex support needs in service re-design and decision making, and will trial child-led service initiatives. It will also explore organisational barriers to including young people in policy debate and service decision-making. Expected outcomes includ ....Re-conceptualising services from the perspectives of young people. This project aims to contribute the perspectives and voices of vulnerable young people to debates on the need for service reform. It will actively engage children and teens who have complex support needs in service re-design and decision making, and will trial child-led service initiatives. It will also explore organisational barriers to including young people in policy debate and service decision-making. Expected outcomes include increased knowledge of how to effectively engage young people, and understanding of the impact of their participation both for young people and for services. Read moreRead less