Modelling mean and dispersion using fixed and random effects. The aims of the project are to develop methods for joint mean and dispersion modelling using fixed and random effects, in the generalized linear models context and for Gaussian longitudinal data. The significance is the more efficient, precise and appropriate analysis of data arising from many areas of application. The expected outcomes are therefore better methods of analysis, software to carry the analyses out, and potentially impor ....Modelling mean and dispersion using fixed and random effects. The aims of the project are to develop methods for joint mean and dispersion modelling using fixed and random effects, in the generalized linear models context and for Gaussian longitudinal data. The significance is the more efficient, precise and appropriate analysis of data arising from many areas of application. The expected outcomes are therefore better methods of analysis, software to carry the analyses out, and potentially important results in applications.Read moreRead less
Classification methods for providing personalised and class decisions. This project provides a novel approach to the clustering of multivariate samples on entities in a class that automatically matches the sample clusters across the entities, allowing for inter-sample variation between the samples in a class. The project aims to develop a widely applicable, mixture-model-based framework for the simultaneous clustering of multivariate samples with inter-sample variation in a class and for the mat ....Classification methods for providing personalised and class decisions. This project provides a novel approach to the clustering of multivariate samples on entities in a class that automatically matches the sample clusters across the entities, allowing for inter-sample variation between the samples in a class. The project aims to develop a widely applicable, mixture-model-based framework for the simultaneous clustering of multivariate samples with inter-sample variation in a class and for the matching of the clusters across the entities in the class. The project will use a statistical approach to automatically match the clusters, since the overall mixture model provides a template for the class. It will provide a basis for discriminating between different classes in addition to the identification of atypical data points within a sample and of anomalous samples within a class. Key applications include biological image analysis and the analysis of data in flow cytometry which is one of the fundamental research tools for the life scientist.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE160101565
Funder
Australian Research Council
Funding Amount
$330,000.00
Summary
Flexible data modelling via skew mixture models:challenges and applications. This project seeks to explore new models for handling data with non-normal features. Parametric distributions are fundamental to statistical modelling and inference. For centuries, the ‘normal’ distribution has been the dominant model for continuous data. However, real data rarely satisfy the assumption of normality. There is thus a strong demand for more flexible distributions. This project aims to develop new methodol ....Flexible data modelling via skew mixture models:challenges and applications. This project seeks to explore new models for handling data with non-normal features. Parametric distributions are fundamental to statistical modelling and inference. For centuries, the ‘normal’ distribution has been the dominant model for continuous data. However, real data rarely satisfy the assumption of normality. There is thus a strong demand for more flexible distributions. This project aims to develop new methodologies in finite mixture modelling using skew component distributions to provide better models for handling data with non-normal features (such as skewness, heavy/light tails, and multimodality). Applications may include security intrusion detection, clinical diagnosis and prognosis, and flow and mass cytometry.Read moreRead less
Designing microarray experiments. Microarrays are powerful tools for surveying the expression levels of many thousands of genes simultaneously. They belong to the new genomics technologies which have important applications in the biological, pharmaceutical and agricultural sciences. There are many sources of uncertainty in microarray experimentation and good statistical designs are essential for ensuring that the effects of interest to scientists are accurately and precisely measured. This Pr ....Designing microarray experiments. Microarrays are powerful tools for surveying the expression levels of many thousands of genes simultaneously. They belong to the new genomics technologies which have important applications in the biological, pharmaceutical and agricultural sciences. There are many sources of uncertainty in microarray experimentation and good statistical designs are essential for ensuring that the effects of interest to scientists are accurately and precisely measured. This Project will develop novel designs for microarray experiments and focus on the advancement of topics crucial to Australia's success in technological research.
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ARC Centre of Excellence for Mathematical and Statistical Frontiers of Big Data, Big Models, New Insights. In today's world, massive amounts of data in a variety of forms are collected daily from a multitude of sources. Many of the resulting data sets have the potential to make vital contributions to society, business and government, as well as impact on international developments, but are so large or complex that they are difficult to process and analyse using traditional tools. The aim of this ....ARC Centre of Excellence for Mathematical and Statistical Frontiers of Big Data, Big Models, New Insights. In today's world, massive amounts of data in a variety of forms are collected daily from a multitude of sources. Many of the resulting data sets have the potential to make vital contributions to society, business and government, as well as impact on international developments, but are so large or complex that they are difficult to process and analyse using traditional tools. The aim of this Centre is to create innovative mathematical and statistical models that can uncover the knowledge concealed within the size and complexity of these big data sets, with a focus on using the models to deliver insight into problems vital to the Centre's Collaborative Domains: Healthy People, Sustainable Environments and Prosperous Societies.Read moreRead less
Complexity Constrained Iterative Information Processing. The contribution of Information and Communications Technologies to the National Economy has been widely recognized. ICT enables wealth creation, employment and exports, and underpins many innovation processes. Immediate project benefits will be: Contribution to the knowledge base and fundamental capabilities in high-speed wireless communications networks; Education of future Australian academic and industrial innovators; Raising the inter ....Complexity Constrained Iterative Information Processing. The contribution of Information and Communications Technologies to the National Economy has been widely recognized. ICT enables wealth creation, employment and exports, and underpins many innovation processes. Immediate project benefits will be: Contribution to the knowledge base and fundamental capabilities in high-speed wireless communications networks; Education of future Australian academic and industrial innovators; Raising the international profile of Australian research in the area of information technology. Applied development of the outcomes will lead to the generation of valuable intellectual property. Close links to Australian industry ensures that Australian ICT companies stand to gain commercial advantage.Read moreRead less
Iterative Architechtures for Data Communications. Growing markets for data intensive applications such as real-time video or speech necessitate continual improvements of communications systems. Iterative information processing algorithms have recently received attention for communications equipment design, however theoretical understanding of these methods is still lacking. Within an iterative processing paradigm, the project aim is the optimization of complex communications systems subject to c ....Iterative Architechtures for Data Communications. Growing markets for data intensive applications such as real-time video or speech necessitate continual improvements of communications systems. Iterative information processing algorithms have recently received attention for communications equipment design, however theoretical understanding of these methods is still lacking. Within an iterative processing paradigm, the project aim is the optimization of complex communications systems subject to constraints on computational complexity. Theoretical analysis and design methodologies for such systems will be developed, resulting in basic contributions to statistical science and in cheaper communications infrastructures supporting a wider range of services through better use of limited bandwidth, power and computational complexity.Read moreRead less