Developmental trajectory of tongue control for speech with real-time MRI. This project aims to evaluate the developmental trajectory of tongue control during speech, relating dynamic 3D vocal tract modelling to the acoustic signal. By optimising real-time MRI technology to capture and model articulatory movements, the project expects to accelerate understanding of how tongue control for speech is developed, mastered, and perturbed by factors such as rapid growth and foreign accent. Expected outc ....Developmental trajectory of tongue control for speech with real-time MRI. This project aims to evaluate the developmental trajectory of tongue control during speech, relating dynamic 3D vocal tract modelling to the acoustic signal. By optimising real-time MRI technology to capture and model articulatory movements, the project expects to accelerate understanding of how tongue control for speech is developed, mastered, and perturbed by factors such as rapid growth and foreign accent. Expected outcome is a new understanding of how different speakers' vocal tracts change and how speech is reshaped, informed by real physiological data. Significant benefits will be realised through refined methods and theory development for diverse fields e.g. linguistics, speech science, and automatic speech recognition/synthesis. Read moreRead less
Speech recognition adaptation for low resource populations. Automatic speech recognition is an essential attribute of mobile devices and consumer electronics. Unfortunately, as these systems are trained with adult speech, they perform poorly when used by children and people with speaking difficulties. The lack of available training speech from these groups makes developing models for them difficult. We will investigate efficient model adaptation methods that use minimal training data to adapt ex ....Speech recognition adaptation for low resource populations. Automatic speech recognition is an essential attribute of mobile devices and consumer electronics. Unfortunately, as these systems are trained with adult speech, they perform poorly when used by children and people with speaking difficulties. The lack of available training speech from these groups makes developing models for them difficult. We will investigate efficient model adaptation methods that use minimal training data to adapt existing adult speech recognition models for use with children and people with speaking difficulties. The intended outcomes will improve access to automatic speech recognition systems for Australians whose communication with speech-controlled environmental and educational devices is currently restricted.Read moreRead less
Ultra-low fouling active surfaces. This project aims to develop chemistries and fabrication approaches through innovative materials evaluation to develop ultra-low fouling active electrode surfaces. Development of ultra-low fouling surfaces will have significant impact in a range of applications where system or device failure is attributed to fouling. The growing field of bionics, where implantable electronic devices interface directly with the nervous system, is one such device. The expected ou ....Ultra-low fouling active surfaces. This project aims to develop chemistries and fabrication approaches through innovative materials evaluation to develop ultra-low fouling active electrode surfaces. Development of ultra-low fouling surfaces will have significant impact in a range of applications where system or device failure is attributed to fouling. The growing field of bionics, where implantable electronic devices interface directly with the nervous system, is one such device. The expected outcomes will be an understanding of the material requirements that lead to the elimination of protein and cell accumulation at surfaces that degrades the performance and lifetime of these implants. The findings will benefit any application where fouling is a problem.Read moreRead less
Biological determinants of the safety and stability of neuroprosthetic stimulation electrodes. Performance of cochlear implants and the quality of sound perceived by patients is strongly related to electrode impedance. Electrode impedance fluctuates relative to the implant electrical activity, but the mechanisms which cause this are not clear. This project aims to investigate the role of protein adsorption in electrode performance, including impedance and material dissolution. To enable these in ....Biological determinants of the safety and stability of neuroprosthetic stimulation electrodes. Performance of cochlear implants and the quality of sound perceived by patients is strongly related to electrode impedance. Electrode impedance fluctuates relative to the implant electrical activity, but the mechanisms which cause this are not clear. This project aims to investigate the role of protein adsorption in electrode performance, including impedance and material dissolution. To enable these investigations a new biomimetic analogue of the perilymph (cochlea fluid) is intended to be developed. Additionally, the project aims to investigate two strategies to minimise impedance changes: small pulse electrode cleaning and antifouling coatings. Understanding and control of factors influencing electrode stability aim to facilitate next-generation implant designs.Read moreRead less
Targeting electrical stimulation of neural tissue. This project aims to develop a platform of mathematical methods for targeting electrical stimulation of neural tissue. The proposed methods work by selecting the amplitude and polarity of each stimulating electrode in an array based on a desired pattern of neural activation. The algorithms are particularly applicable to high-density electrode arrays. The project will work with an Australian industry leader to provide significant benefits to Aust ....Targeting electrical stimulation of neural tissue. This project aims to develop a platform of mathematical methods for targeting electrical stimulation of neural tissue. The proposed methods work by selecting the amplitude and polarity of each stimulating electrode in an array based on a desired pattern of neural activation. The algorithms are particularly applicable to high-density electrode arrays. The project will work with an Australian industry leader to provide significant benefits to Australia’s high-tech sector through increased knowledge and capacity.Read moreRead less
Feedthrough technologies for polymeric encapsulated active implants. The project will address the scientific challenges of signal transfer between tissue and novel active implantable medical devices, with major implications for cochlear implant manufacture. This will lead to improvements in the quality of life of the hearing-impaired, and will make an important contribution to the development of other sensory implants.
The neural dynamics of real-time processing in the brain. The aim of this project is to investigate a new model for predictive coding of sensory processing in the brain in which the brain compensates for the time delays in neural transmission by maintaining a real-time temporal alignment of the neural activity. This results in a representation of sensory information that is aligned in time across the cortex, offering a new fundamental principle for how the brain functions in a highly dynamic wor ....The neural dynamics of real-time processing in the brain. The aim of this project is to investigate a new model for predictive coding of sensory processing in the brain in which the brain compensates for the time delays in neural transmission by maintaining a real-time temporal alignment of the neural activity. This results in a representation of sensory information that is aligned in time across the cortex, offering a new fundamental principle for how the brain functions in a highly dynamic world whose outcomes would provide a deeper understanding of brain function. It could also have profound significance for artificial intelligence and brain-inspired technologies, as well as benefit neural sensory prostheses and brain-machine interfaces.Read moreRead less
The encoding of friction by tactile mechanoreceptors - the key to fingertip force control during dexterous object manipulation by humans. Unmatched human ability to control the hand so that brittle objects are gently held without slipping, or being crushed by excessive force rely on sophisticated tactile sense in the fingertips. This project will record and analyse signals which human nerves are sending from fingertip receptors to the brain centres controlling hand actions.
Sensory mechanisms underlying human dexterity in object manipulation. This project aims to understand the sensory mechanisms and biomechanics underlying sensory encoding. Tactile sensory information is crucial for controlling grip forces so that delicate objects are held without slipping, or being crushed by excessive force. This project will record signals from single human tactile receptors using microneurography. By modelling the neural data with skin biomechanical events, this project aims t ....Sensory mechanisms underlying human dexterity in object manipulation. This project aims to understand the sensory mechanisms and biomechanics underlying sensory encoding. Tactile sensory information is crucial for controlling grip forces so that delicate objects are held without slipping, or being crushed by excessive force. This project will record signals from single human tactile receptors using microneurography. By modelling the neural data with skin biomechanical events, this project aims to reveal sensory mechanisms underlying the human ability to manipulate objects and use tools. This research could lead to next generation sensory-controlled prosthetics and robotic manipulators.Read moreRead less
Plant based foods: Towards sustainable and acceptable meat analogues. The project aims to address the need for engineering plant-based food products to deliver a sensory experience akin to meat. The project expects to generate new knowledge on the structural drivers for emulating meat-like texture and taste within burger products. Expected outcomes of this project include new ingredients and food characterisation methodologies, including rheology and sensory, which can be employed in rational ....Plant based foods: Towards sustainable and acceptable meat analogues. The project aims to address the need for engineering plant-based food products to deliver a sensory experience akin to meat. The project expects to generate new knowledge on the structural drivers for emulating meat-like texture and taste within burger products. Expected outcomes of this project include new ingredients and food characterisation methodologies, including rheology and sensory, which can be employed in rational food structure design. This should provide significant benefits in enhancing the consumer acceptance of plant-based foods that is required to support the rapidly growing market opportunity for them and sustainable food production.Read moreRead less