Relationship of retinal directionality to human retinal anatomy variations. This project aims to improve measurement of retinal directionality, which is the reduction in brightness when a light beam’s entry into the human eye is shifted from the centre to the edge of the pupil. This influences retinal image quality and can be used to measure changes in shape of the peripheral eye. This project will apply advanced technologies in holography, and heads-up displays to explore how retinal directiona ....Relationship of retinal directionality to human retinal anatomy variations. This project aims to improve measurement of retinal directionality, which is the reduction in brightness when a light beam’s entry into the human eye is shifted from the centre to the edge of the pupil. This influences retinal image quality and can be used to measure changes in shape of the peripheral eye. This project will apply advanced technologies in holography, and heads-up displays to explore how retinal directionality changes during accommodation (focusing). The expected outcome is improved understanding of retinal stretching changes during focusing. The benefit is that the project will lead to advancements in retinal imaging.Read moreRead less
Novel psychophysical paradigms for examining predictive coding in vision. Human vision is shaped by predictive signals in the brain. Despite a century of speculation, we do not know how this interplay is implemented - particularly during natural viewing. This project will establish and validate new psychophysical protocols for investigating predictive coding in human vision. Experiments will involve natural viewing and eye tracking, so results will generalize to real-life. Studies will seek to c ....Novel psychophysical paradigms for examining predictive coding in vision. Human vision is shaped by predictive signals in the brain. Despite a century of speculation, we do not know how this interplay is implemented - particularly during natural viewing. This project will establish and validate new psychophysical protocols for investigating predictive coding in human vision. Experiments will involve natural viewing and eye tracking, so results will generalize to real-life. Studies will seek to clarify how predictions are formed and signalled. This could inform future developments in artificial intelligence, as that cutting edge technology continues to be informed by our understanding of predictive coding in human vision.Read moreRead less
Using visual science to reduce the dangers of night driving. This project aims to develop novel tests of visual function relevant to the modern night driving environment. Night driving is challenging for all drivers and has been linked to poor visibility under low light conditions. This project will characterise the visual challenges of the modern night driving environment, develop visual tests that incorporate the dynamic light levels typical of night-time roads and assess the association of th ....Using visual science to reduce the dangers of night driving. This project aims to develop novel tests of visual function relevant to the modern night driving environment. Night driving is challenging for all drivers and has been linked to poor visibility under low light conditions. This project will characterise the visual challenges of the modern night driving environment, develop visual tests that incorporate the dynamic light levels typical of night-time roads and assess the association of these tests with night driving performance. The outcomes will contribute new knowledge regarding dynamic visual processing and the ageing visual system and will inform vision testing, potential interventions to improve visual function for night driving and reduce the dangers of night driving.Read moreRead less
How the brain produces speech: Neuronal oscillations to neuromodulation. Speech is crucial for facilitating human communication through language, yet there is a lack of clarity about where, when and what type of activity occurs in the brain during key stages of production. This project will use intracranial recordings to characterise neuronal oscillations in combination with direct electrical stimulation, functional neuroimaging and non-invasive brain stimulation to establish critical areas and ....How the brain produces speech: Neuronal oscillations to neuromodulation. Speech is crucial for facilitating human communication through language, yet there is a lack of clarity about where, when and what type of activity occurs in the brain during key stages of production. This project will use intracranial recordings to characterise neuronal oscillations in combination with direct electrical stimulation, functional neuroimaging and non-invasive brain stimulation to establish critical areas and their timecourses with millisecond resolution. The outcome will be a better theoretical account of the brain mechanisms involved in spoken production. The benefit of this new theoretical account will be a better basis for prevention of post-surgical language impairment and neuromodulatory treatments after brain injury.Read moreRead less
A more sound approach to the neurobiology of language. How does the brain attain spoken language? Current neurobiological models assume either implicitly or explicitly that there is no relationship between a word's sound and its meaning. Yet considerable evidence shows this strong assumption about the arbitrariness of language is invalid. This project will use a combination of behavioural, neuroimaging and computational studies to characterise how the brain processes statistical regularities in ....A more sound approach to the neurobiology of language. How does the brain attain spoken language? Current neurobiological models assume either implicitly or explicitly that there is no relationship between a word's sound and its meaning. Yet considerable evidence shows this strong assumption about the arbitrariness of language is invalid. This project will use a combination of behavioural, neuroimaging and computational studies to characterise how the brain processes statistical regularities in sound-to-meaning correspondences as probabilistic cues to attain spoken language. The outcome will be a better neural account of language comprehension and production. The benefit of this new account will be a stronger basis for assessment and treatment of developmental and acquired language impairments.Read moreRead less
Voices of Regional Australia: The linguistic patterning of local attachment. This project aims to investigate language and social dynamics among regional Australians, who, despite representing one third of the population, have been often neglected in the research to date. The project expects to generate new knowledge around regional attachment and the impact that has on speech patterns, adapting for the first time recently developed international metrics to the Australian context. Expected outco ....Voices of Regional Australia: The linguistic patterning of local attachment. This project aims to investigate language and social dynamics among regional Australians, who, despite representing one third of the population, have been often neglected in the research to date. The project expects to generate new knowledge around regional attachment and the impact that has on speech patterns, adapting for the first time recently developed international metrics to the Australian context. Expected outcomes include a better understanding of models of language change across urban and rural areas, and a novel dataset recording the stories of regional Australians, and in particular, their experiences facing bushfire. This should provide significant benefits as a record of life, language and community in regional Australia.Read moreRead less
A honking horn can blind you: how sudden distractions redirect attention. This project aims to investigate the sudden offset of distraction and its effects. Distraction can have a devastating impact on our ability to pay attention. This project derives its approach to distraction from recent neurophysiological advances in understanding the Locus Coeruleus–Norepinephrine system. The project intends to establish the role of the Locus Coeruleus in sudden distraction and to examine how sudden distra ....A honking horn can blind you: how sudden distractions redirect attention. This project aims to investigate the sudden offset of distraction and its effects. Distraction can have a devastating impact on our ability to pay attention. This project derives its approach to distraction from recent neurophysiological advances in understanding the Locus Coeruleus–Norepinephrine system. The project intends to establish the role of the Locus Coeruleus in sudden distraction and to examine how sudden distraction interacts with both environmental and internal factors. The outcomes of the research may lead to improvements in technology to enhance road safety and reduce the social and physical costs of distraction-related accidents. This should provide significant benefits such as informing policies on distraction-while-driving to make Australia’s roads safer.Read moreRead less
Linking human brain structure to function with ultra-high resolution fMRI. This project will examine the structure and function of the sensory cortex of the human brain using ultra-high resolution functional magnetic resonance imaging (7 Tesla MRI). The project pushes new boundaries for resolution with ultra-high field MRI (7 Tesla) and, as such, will advance techniques for the acquisition, analysis, and computational modelling of high-resolution fMRI brain imaging, providing detail of the funct ....Linking human brain structure to function with ultra-high resolution fMRI. This project will examine the structure and function of the sensory cortex of the human brain using ultra-high resolution functional magnetic resonance imaging (7 Tesla MRI). The project pushes new boundaries for resolution with ultra-high field MRI (7 Tesla) and, as such, will advance techniques for the acquisition, analysis, and computational modelling of high-resolution fMRI brain imaging, providing detail of the functional organisation of the sensory cortex at a level never previously possible in the living human brain. This will provide new understanding of the neural-level networks that underpin attention and touch perception in the human brain.Read moreRead less
Understanding the neural dynamics of integrated perceptual decisions. This project aims to characterise the brain processes involved in perceptual decision-making. While scientists have a good understanding of how people make decisions about the properties of individual sensory inputs, much less is known about how the brain integrates information across multiple sensory sources that differ in their salience and fidelity. The project expects to elucidate the neural mechanisms responsible for thes ....Understanding the neural dynamics of integrated perceptual decisions. This project aims to characterise the brain processes involved in perceptual decision-making. While scientists have a good understanding of how people make decisions about the properties of individual sensory inputs, much less is known about how the brain integrates information across multiple sensory sources that differ in their salience and fidelity. The project expects to elucidate the neural mechanisms responsible for these integrative perceptual decisions, using a combination of brain imaging and behavioural measures, computational modelling and real-time neurofeedback. This should provide significant benefits for developing more effective approaches to training individuals in professions that rely on optimal decision-making skills.Read moreRead less
Subcortical control of human reaching? This project will test a radical new hypothesis about how the human brain generates visually guided behaviour. Conventional thinking assumes that visuomotor control of limb movements occurs exclusively within the cerebral cortex. However, the project team’s recent observations of extremely rapid visually guided muscle activity strongly imply that the human brain controls reaching movements via more primitive midbrain and brainstem structures. The project’s ....Subcortical control of human reaching? This project will test a radical new hypothesis about how the human brain generates visually guided behaviour. Conventional thinking assumes that visuomotor control of limb movements occurs exclusively within the cerebral cortex. However, the project team’s recent observations of extremely rapid visually guided muscle activity strongly imply that the human brain controls reaching movements via more primitive midbrain and brainstem structures. The project’s hypotheses challenge long-standing ideas about the functional organisation of the human brain and may have wide-ranging implications for the design of human-machine interfaces as well as training protocols in rehabilitation, industry, and sport.Read moreRead less