Neurocognitive substrates of naming facilitation in aphasia. This research directly addresses the national research priority goal of ageing well, ageing productively, by providing foundational knowledge for improved outcomes in the growing population of individuals in Australia with language impairments from age-related disease. Outcomes of the proposed research will include (1) development of a new theory of word production which can improve treatment of language impairment, (2) an enhanced und ....Neurocognitive substrates of naming facilitation in aphasia. This research directly addresses the national research priority goal of ageing well, ageing productively, by providing foundational knowledge for improved outcomes in the growing population of individuals in Australia with language impairments from age-related disease. Outcomes of the proposed research will include (1) development of a new theory of word production which can improve treatment of language impairment, (2) an enhanced understanding of the cognitive and brain mechanisms involved in word production and its treatment after stroke, and (3) postgraduate training in state-of-the-art cognitive neuroimaging and language neuroscience research. Read moreRead less
Children's Changing Speech Error Patterns: Articulating, Listening, and Thinking. When children are learning to talk, they make many errors of pronunciation. Between speech onset and five years of age, their pronunciations change, gradually approaching adult pronunciations of words. Most children share the same error patterns, although 6% have difficulty acquiring intelligible speech, that affects their academic and social development. The investigation will examine factors that contribute to ....Children's Changing Speech Error Patterns: Articulating, Listening, and Thinking. When children are learning to talk, they make many errors of pronunciation. Between speech onset and five years of age, their pronunciations change, gradually approaching adult pronunciations of words. Most children share the same error patterns, although 6% have difficulty acquiring intelligible speech, that affects their academic and social development. The investigation will examine factors that contribute to the acquisition of speech in normally developing and speech-disordered populations: oro-motor skills, auditory and cognitive processing. Experiments will determine the importance of each domain for speech development. The efficacy of a novel intervention programme for children with speech disorders will be evaluated.Read moreRead less
Stuttering in childhood: Patterns of recovery and persistence. This project will benefit the 1 in 20 Australian children who stutter and their families. We will learn for the first time how stuttering impacts on child development in the early school years and document the relationship between stuttering and other childhood conditions. The study will produce much needed information about recovery from stuttering and stuttering persistence. Therefore new knowledge will result to inform the scienti ....Stuttering in childhood: Patterns of recovery and persistence. This project will benefit the 1 in 20 Australian children who stutter and their families. We will learn for the first time how stuttering impacts on child development in the early school years and document the relationship between stuttering and other childhood conditions. The study will produce much needed information about recovery from stuttering and stuttering persistence. Therefore new knowledge will result to inform the scientific community and provide professionals and families with much needed evidence-based information about stuttering progression. Together this information will inform intervention approaches and help direct resources to those children who need them most. Read moreRead less
Communication outcomes of preterm children: prevalence, description and intervention. Premature birth places children at risk of major disability, yet the majority of children are considered neurologically normal and disability free. However in follow-up studies at school age, preterm children are found to have lower verbal and nonverbal abilities that affects their academic and social development. Preterm children are six times more likely to require special educational support. This investigat ....Communication outcomes of preterm children: prevalence, description and intervention. Premature birth places children at risk of major disability, yet the majority of children are considered neurologically normal and disability free. However in follow-up studies at school age, preterm children are found to have lower verbal and nonverbal abilities that affects their academic and social development. Preterm children are six times more likely to require special educational support. This investigation will examine the communication skills, cognitive processes and academic progress of children born preterm. The findings will provide an evidence base for decisions about monitoring and intervention of preterm infants at greater risk for poorer speech-language and academic outcomes.Read moreRead less
A study of early stuttering. Stuttering affects 1 in 20 Australian children. Stuttering disrupts and prevents normal verbal communication, significantly interferes with social interaction and can affect the attainment of educational and occupational potential. Australia leads the world in stuttering research. This innovative study will document the onset of stuttering and describe its progression, an area that is not well described or understood. This project will contribute new knowledge about ....A study of early stuttering. Stuttering affects 1 in 20 Australian children. Stuttering disrupts and prevents normal verbal communication, significantly interferes with social interaction and can affect the attainment of educational and occupational potential. Australia leads the world in stuttering research. This innovative study will document the onset of stuttering and describe its progression, an area that is not well described or understood. This project will contribute new knowledge about the onset of stuttering thereby benefiting children worldwide and their families. It will inform clinical practice and improve the evidence underpinning the advice given to parents of children who stutter.Read moreRead less
How does dopamine modulate adult new word learning? Stroke is a chronic disease of increasing prevalence with increasing age. There is a critical need to develop more effective treatments of communication disorders in this population. One way of achieving this is to combine certain drugs with language therapy. Through studying how these drugs influence language, this research will provide vital knowledge for developing effective forms of pharmacotherapy for adults with language disorders after b ....How does dopamine modulate adult new word learning? Stroke is a chronic disease of increasing prevalence with increasing age. There is a critical need to develop more effective treatments of communication disorders in this population. One way of achieving this is to combine certain drugs with language therapy. Through studying how these drugs influence language, this research will provide vital knowledge for developing effective forms of pharmacotherapy for adults with language disorders after brain injury. More effective language rehabilitation can have direct positive consequences on the ability to regain and maintain employment and social relationships after stroke or brain injury and will address the large and growing social and economic cost to the nation.Read moreRead less
A functional imaging study of semantic processing modulated by dopamine. The role of dopamine in language processing is largely unknown, despite emerging evidence that dopaminergic alterations can modulate language in schizophrenia, Parkinson's disease, and healthy individuals. The research aims to reveal the neural and behavioural correlates of dopaminergic modulation of semantic processing using neuroimaging in healthy individuals who have ingested levodopa. It is hypothesised that levodopa wi ....A functional imaging study of semantic processing modulated by dopamine. The role of dopamine in language processing is largely unknown, despite emerging evidence that dopaminergic alterations can modulate language in schizophrenia, Parkinson's disease, and healthy individuals. The research aims to reveal the neural and behavioural correlates of dopaminergic modulation of semantic processing using neuroimaging in healthy individuals who have ingested levodopa. It is hypothesised that levodopa will modulate brain activity under circumstances where there is heightened semantic competition, consistent with a contemporary theory of dopaminergic cognitive control. The expected outcome of the research is an increased understanding of the interactions between dopamine, the language faculty, and associated neural systems.Read moreRead less
Enhancing Language Learning in Ageing With Exercise. This project aims to determine if exercise improves language learning and consolidation in ageing. There is now compelling evidence for the benefits of exercise on cognition in older adults, however, it is unclear whether exercise improves age-related language problems. The project plans to examine exercise-induced changes in brain activity and biomarkers in an innovative set of studies that seeks to identify the brain mechanisms involved. The ....Enhancing Language Learning in Ageing With Exercise. This project aims to determine if exercise improves language learning and consolidation in ageing. There is now compelling evidence for the benefits of exercise on cognition in older adults, however, it is unclear whether exercise improves age-related language problems. The project plans to examine exercise-induced changes in brain activity and biomarkers in an innovative set of studies that seeks to identify the brain mechanisms involved. The findings are expected to contribute to theories of word learning and cognitive ageing and should advance our understanding of how exercise may be harnessed to optimise language and cognition. This would have practical applications in a range of populations with language and learning difficulties.Read moreRead less
Brain structure and function of neonates at risk for stuttering. The aim of the project is to determine whether the brain abnormalities that have been found in people who stutter are present at birth. The hypothesis is that the brains of neonates who subsequently start to stutter will differ significantly from those who do not. This is the first project to investigate the brains of infants before they start to stutter.
Audio-visual Information for Speech-hand Gestures. How does audio-visual information influence human movement and communication? We will investigate whether speech and hand gestures involve shared information about the timing of rhythmic movements. Using dynamical systems theory and brain imaging techniques, we will study rhythms that emerge during simultaneous speaking and finger tapping in both stutterers and non-stutterers, and in left-handers and right-handers. The communicative interaction ....Audio-visual Information for Speech-hand Gestures. How does audio-visual information influence human movement and communication? We will investigate whether speech and hand gestures involve shared information about the timing of rhythmic movements. Using dynamical systems theory and brain imaging techniques, we will study rhythms that emerge during simultaneous speaking and finger tapping in both stutterers and non-stutterers, and in left-handers and right-handers. The communicative interaction of two persons performing speech-hand gestures will be examined. Results will clarify how brain asymmetry affects gestural coordination in stutterers, how stuttering can be treated, and the hypothesis that speech and language evolved from a communication system based on hand gestures.
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