Engineering and Assembly of Bioinspired Nanostructured Materials. Scientific and technological advances at the frontiers of nano- and bio-technology are poised to revolutionise healthcare and medicine. This project will involve the design, synthesis and engineering of functional biopolymer building blocks. These 'smart' biopolymers will then be assembled into responsive, nanostructured materials for targeted drug delivery and biosensing applications. These materials are expected to ultimately ha ....Engineering and Assembly of Bioinspired Nanostructured Materials. Scientific and technological advances at the frontiers of nano- and bio-technology are poised to revolutionise healthcare and medicine. This project will involve the design, synthesis and engineering of functional biopolymer building blocks. These 'smart' biopolymers will then be assembled into responsive, nanostructured materials for targeted drug delivery and biosensing applications. These materials are expected to ultimately have health benefits for Australian citizens and contribute to the development of a robust Australian nanobiotechnology industry. The project will also provide excellent opportunities for the development of outstanding young scientists and will foster exciting, multidisciplinary collaborations.Read moreRead less
Synthesis and Functionalisation of Advanced Polymer Films and Particles. Scientific and technological advances at the frontiers of nano- and biotechnology are poised to revolutionise the scope of treatment and healthcare options. This project will involve the synthesis of engineered polymer building blocks with the capability for multifunctional and intelligent response. These smart polymers will then be assembled into responsive nanostructured materials for drug delivery and biosensing applica ....Synthesis and Functionalisation of Advanced Polymer Films and Particles. Scientific and technological advances at the frontiers of nano- and biotechnology are poised to revolutionise the scope of treatment and healthcare options. This project will involve the synthesis of engineered polymer building blocks with the capability for multifunctional and intelligent response. These smart polymers will then be assembled into responsive nanostructured materials for drug delivery and biosensing applications. These materials are expected to have health benefits for Australian citizens and will contribute to a world-leading nanobiotechnology industry. The project will also provide development opportunities for young scientists and will also foster multidisciplinary collaborations within both Australia and abroad.Read moreRead less
Nanoscale Coating and Biomodification of Colloids for Biological Applications. The research entails the preparation of novel biofunctional colloids of nanometer to micrometer dimensions and their utilisation in biological applications. Self-assembly processes will be exploited to achieve nanoscale biomodification of technologically important colloid particles, including latex beads and rare earth and semiconductor nanoparticles. The studies conducted will generate fundamental knowledge pertainin ....Nanoscale Coating and Biomodification of Colloids for Biological Applications. The research entails the preparation of novel biofunctional colloids of nanometer to micrometer dimensions and their utilisation in biological applications. Self-assembly processes will be exploited to achieve nanoscale biomodification of technologically important colloid particles, including latex beads and rare earth and semiconductor nanoparticles. The studies conducted will generate fundamental knowledge pertaining to the underlying factors that govern the formation of biofunctional colloid particles through self-assembly. This is essential for the development of tailored colloids that will meet the demands placed on nanomaterials synthesis and performance by nanotechnology. The colloids prepared will find new applications in medicine, biocatalysis and bioassays.Read moreRead less
Beyond Microarrays: Nano-Scaled Devices for High Throughput Biomolecular Sensing. Current developments in Nanoscience and Nanotechnology hold many promises in terms of revolutionising our industrial base, transforming biology, medical science and practice. This project strives to achieve some of these aims by, for the first time, building and testing nano-scaled devices with the capability to 'read' massive amounts of biological information. With the recent completion of the Human Genome proje ....Beyond Microarrays: Nano-Scaled Devices for High Throughput Biomolecular Sensing. Current developments in Nanoscience and Nanotechnology hold many promises in terms of revolutionising our industrial base, transforming biology, medical science and practice. This project strives to achieve some of these aims by, for the first time, building and testing nano-scaled devices with the capability to 'read' massive amounts of biological information. With the recent completion of the Human Genome project, major opportunities exist to provide spectacular advances in human health care (eg, via personalised medicine) provided that appropriate high-throughput biological reading devices can be developed. In developing such devices, this project also aims to substantially catalyse the Australian Nanotechnology/Biotechnology industry.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100121
Funder
Australian Research Council
Funding Amount
$270,000.00
Summary
An integrated system for characterisation of mechanical behaviour of bio- and nanomaterials at micro and nano scales in Queensland. Australia's material sciences will benefit from a new integrated system capable of microforce and nanomechanical testing of biomaterials, polymers and thin films, medical devices and electronics at the micro and nano scales. This facility will support ground-breaking research. It will help promote strategic collaboration and ensure the competitiveness of related and ....An integrated system for characterisation of mechanical behaviour of bio- and nanomaterials at micro and nano scales in Queensland. Australia's material sciences will benefit from a new integrated system capable of microforce and nanomechanical testing of biomaterials, polymers and thin films, medical devices and electronics at the micro and nano scales. This facility will support ground-breaking research. It will help promote strategic collaboration and ensure the competitiveness of related and emerging industries.Read moreRead less
Designed Delivery - Novel Hydrogels for Drug Delivery from Precisely-Structured Networks. This project will lead to the development of new biodegradable biomaterials ideally suited to many applications in drug delivery and tissue engineering. The understanding of their properties will be built on comprehensive models for diffusion of molecules through the material. The availability of these new biomaterials will facilitate future developments in drug delivery, and will ultimately lead to improve ....Designed Delivery - Novel Hydrogels for Drug Delivery from Precisely-Structured Networks. This project will lead to the development of new biodegradable biomaterials ideally suited to many applications in drug delivery and tissue engineering. The understanding of their properties will be built on comprehensive models for diffusion of molecules through the material. The availability of these new biomaterials will facilitate future developments in drug delivery, and will ultimately lead to improved medical outcomes in many areas such as tissue and bone regeneration. The materials designed in this project will help position the Australian biotechnology and pharmaceutical industries to take advantage of the more than $100B USD market (US alone; growth ~ 10% p.a.) in drug delivery.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE170100096
Funder
Australian Research Council
Funding Amount
$325,000.00
Summary
High resolution atomic force microscopy facility for bionanotechnology. This project aims to establish a collaborative high resolution atomic force microscopy facility. Nanoscale surface structure and the complex structure/mechanical-functional relationships underpin many biological processes, and understanding cell systems at the molecular level is expected to lead to scientific knowledge and therapeutic and other biotechnological applications. Expected outcomes include innovations in advanced ....High resolution atomic force microscopy facility for bionanotechnology. This project aims to establish a collaborative high resolution atomic force microscopy facility. Nanoscale surface structure and the complex structure/mechanical-functional relationships underpin many biological processes, and understanding cell systems at the molecular level is expected to lead to scientific knowledge and therapeutic and other biotechnological applications. Expected outcomes include innovations in advanced manufacturing in the pharmaceutical and medical devices industries, underpinning economic returns from new industries.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE240100129
Funder
Australian Research Council
Funding Amount
$530,721.00
Summary
State-of-the-art atomic force microscopy facilities for South Australia. This project aims to transform our national capability in nano-(bio)characterisation by establishing a state-of-the-art atomic force microscopy (AFM) facility in South Australia. The facility will provide unparalleled capabilities not currently available in Australia and will catapult knowledge in multiple fields, from critical minerals and clean energy to mechanobiology. Expected outcomes include more efficient and eco-fri ....State-of-the-art atomic force microscopy facilities for South Australia. This project aims to transform our national capability in nano-(bio)characterisation by establishing a state-of-the-art atomic force microscopy (AFM) facility in South Australia. The facility will provide unparalleled capabilities not currently available in Australia and will catapult knowledge in multiple fields, from critical minerals and clean energy to mechanobiology. Expected outcomes include more efficient and eco-friendly resource recovery and energy production, future foods and cures, and advanced (bio)materials. The project will strengthen and amplify Australia’s capacity and global leadership to translate fundamental nano-scale phenomena and properties into innovative materials, technologies, and processes.Read moreRead less
Special Research Initiatives - Grant ID: SR0354588
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
Integrated Nanoscale Biosystems Network (INBN). The INBN will integrate high-priority research, already identified by the ARC, in materials nanoscience and engineering with nanoscale biology. The INBN will provide the means to consolidate world-class multidisciplinary Australian research groups in existing Centres of Excellence, including several Federation Fellows, into a nanobiotechnology focus. The significant outcomes of INBN are the critical mass of outstanding researchers in the nanobiosci ....Integrated Nanoscale Biosystems Network (INBN). The INBN will integrate high-priority research, already identified by the ARC, in materials nanoscience and engineering with nanoscale biology. The INBN will provide the means to consolidate world-class multidisciplinary Australian research groups in existing Centres of Excellence, including several Federation Fellows, into a nanobiotechnology focus. The significant outcomes of INBN are the critical mass of outstanding researchers in the nanobiosciences, facilitation of innovative research to produce novel intellectual property and provision of pathways into collaborative research with international scientists and industry, and the training and development of the next generation scientists for this emerging discipline.
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Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989341
Funder
Australian Research Council
Funding Amount
$690,000.00
Summary
Advanced NanoBiomaterials Imaging Facility. The convergence of nanotechnology with biotechnology offers unprecedented opportunities to prepare nanomaterials with defined structure and function on the nanometre scale. However, the small length scales involved in nanomaterials present challenges in their characterisation, and in turn, their interaction with biological systems. The Advanced NanoBiomaterials Imaging Facility will provide state-of-the-art equipment for examining the properties of nan ....Advanced NanoBiomaterials Imaging Facility. The convergence of nanotechnology with biotechnology offers unprecedented opportunities to prepare nanomaterials with defined structure and function on the nanometre scale. However, the small length scales involved in nanomaterials present challenges in their characterisation, and in turn, their interaction with biological systems. The Advanced NanoBiomaterials Imaging Facility will provide state-of-the-art equipment for examining the properties of nanomaterials and their interaction with biosystems. The equipment will facilitate the development of new materials that are expected to underpin advances in drug delivery, diagnostics and implant devices, further strengthening Australia's strong reputation in these areas.Read moreRead less