Smart hybrid nano-biomaterials that mimic the pharmaceutical food effect. Smart biomaterials will be developed which when taken orally will act in our gut to improve drug and vitamin uptake. The breakthrough science will drive new pharmaceuticals and nutraceuticals for the future health of Australia, and economic benefits will result through increased exposure to the global market for delivering biomolecules.
Development of functional dendrimer-like inorganic nanomaterials with hierarchical pores for biological applications. This project aims to engineer a series of brand new dendrimer-like mesoporous silica nanoparticles with hierarchical pore structure and favourable surface functionality as nanocarriers to construct a smart delivery system. Unique materials structure and surface functionalisation design can endow the system with advanced characteristics of the co-loading of different therapeutic a ....Development of functional dendrimer-like inorganic nanomaterials with hierarchical pores for biological applications. This project aims to engineer a series of brand new dendrimer-like mesoporous silica nanoparticles with hierarchical pore structure and favourable surface functionality as nanocarriers to construct a smart delivery system. Unique materials structure and surface functionalisation design can endow the system with advanced characteristics of the co-loading of different therapeutic agents and the highly efficient target delivery that are not readily obtainable using other organic or inorganic materials. The proposed delivery systems are of great importance for improving the therapeutic efficiency of complex diseases, and in general, for expanding human’s life span.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE170100021
Funder
Australian Research Council
Funding Amount
$370,000.00
Summary
Orchestrating cellular processes by engineering silicon nanowire architectures. This project aims to improve gene transport by creating low-cost, easily implemented, programmable and controllable silicon nanowire-mediated transfection technology, and to demonstrate high-throughput, parallel trafficking of bioactive payloads. Success would enable the design and fabrication of nano–bio interfaces with closely controlled geometry and architecture, to orchestrate specific cellular processes such as ....Orchestrating cellular processes by engineering silicon nanowire architectures. This project aims to improve gene transport by creating low-cost, easily implemented, programmable and controllable silicon nanowire-mediated transfection technology, and to demonstrate high-throughput, parallel trafficking of bioactive payloads. Success would enable the design and fabrication of nano–bio interfaces with closely controlled geometry and architecture, to orchestrate specific cellular processes such as cellular reprogramming, adhesion, morphology, and differentiation with unprecedented efficiency and predictability. The advance could lead to breakthroughs in fundamental cellular studies, and better understanding of cell behaviour, function and fate.Read moreRead less
Lab-on-a-chip mass spectrometry tools for testing illicit drugs. This project aims to develop fit-for-purpose mass spectrometry tools for roadside and workplace testing of illicit drugs. The technology will be based on nanostructured semiconductor chips that are surface-functionalised to enable molecular capture without extensive sample processing and subsequent detection by a novel combination of techniques. The technology is expected to be applicable to saliva, sweat and urine samples.
Printable technologies for high security documents and consumer products. Printable technologies for high security documents and consumer products. This project aims to develop two next-generation printable security feature technologies to protect users from counterfeiting, which costs the world economy billions in lost revenue and undermines the security of citizens. First, it aims to enhance the security of banknotes by developing printable active device patches with energy harvesting flexible ....Printable technologies for high security documents and consumer products. Printable technologies for high security documents and consumer products. This project aims to develop two next-generation printable security feature technologies to protect users from counterfeiting, which costs the world economy billions in lost revenue and undermines the security of citizens. First, it aims to enhance the security of banknotes by developing printable active device patches with energy harvesting flexible polymers as a power source and thin film graphene/polymer nanomaterial as an electrode/energy storage media. Second, it aims to design invisible carbon nanotube inks for optical authentication via near infrared activation. Both technologies are expected to thwart sophisticated counterfeits, particularly those supported by organised crime.Read moreRead less
Nanodiamond in glass: a new approach to nanosensing. This work will develop optical materials enriched with diamond nanoparticles. This will enable the magnetic field sensitivity of diamond nanoparticles to be combined with the capacity of micro/nanostructured optical fibres to enhance the interaction of light with matter. The outcome will be tools for probing biological processes on the nanoscale.
Discovery Early Career Researcher Award - Grant ID: DE230101637
Funder
Australian Research Council
Funding Amount
$431,318.00
Summary
Heterogeneous Molecular Catalysts for Carbon Dioxide Conversion. This project aims to develop a series of structure-tailored, activity-enhanced and selectivity-oriented heterogeneous molecular catalysts for efficiently converting carbon dioxide (CO2) into value-added fuels and chemicals. Innovations are expected in the rational design and engineering of materials, new mechanistic findings from computation and in-situ characterisation, and breakthroughs in CO2 conversion. Expected outcomes includ ....Heterogeneous Molecular Catalysts for Carbon Dioxide Conversion. This project aims to develop a series of structure-tailored, activity-enhanced and selectivity-oriented heterogeneous molecular catalysts for efficiently converting carbon dioxide (CO2) into value-added fuels and chemicals. Innovations are expected in the rational design and engineering of materials, new mechanistic findings from computation and in-situ characterisation, and breakthroughs in CO2 conversion. Expected outcomes include new synthesis methods, innovative multi-structural engineering strategies, thorough reaction mechanism understanding, and high-performance commercially-relevant CO2 reduction electrolysis. Benefits include a sustainable future for Australia with decreased CO2 emissions and increased green-fuel production.Read moreRead less
Harnessing lipid nano-assembly for next generation functional foods and pharmaceutical products. Nature assembles lipid molecules from our diet into useful structures in our gastrointestinal tract with remarkable precision and versatility. By understanding and harnessing these processes we can design new lipid-based nanomaterials leading to more effective functional foods and pharmaceutical products with reduced side effects.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE140100104
Funder
Australian Research Council
Funding Amount
$500,000.00
Summary
Collaborative facility for high resolution fabrication, imaging, and characterisation of nanostructured materials. Collaborative facility for high resolution fabrication, imaging, and characterisation of nanostructured materials: The development of the next generation of electronic, optical, and biomedical devices requires methods that can quickly manipulate and characterise matter at the nanoscale. This project will establish new tools that will allow researchers to build novel device structure ....Collaborative facility for high resolution fabrication, imaging, and characterisation of nanostructured materials. Collaborative facility for high resolution fabrication, imaging, and characterisation of nanostructured materials: The development of the next generation of electronic, optical, and biomedical devices requires methods that can quickly manipulate and characterise matter at the nanoscale. This project will establish new tools that will allow researchers to build novel device structures and analyse them at nanoscale spatial resolutions. The new facilities are required to meet the demands of a growing number of innovative projects being undertaken within a large multidisciplinary consortium of research groups. The facilities will be housed in state-of-the art laboratories and managed as open access resources for researchers which will enable advances in the areas of energy harvesting, environmental monitoring, and electronics.Read moreRead less