Patterned assemblies of molecules on surfaces. Because of their redox and photophysical properties, artificial porphyrin systems have been designed for applications such as light-harvesting antennae, catalysts and sensors. Control of molecular orientation is required in order to construct practical devices, and in this project methods of assembling porphyrins on surfaces in well-defined patterns will be developed. Sophisticated methods will be used to characterise the films produced in these w ....Patterned assemblies of molecules on surfaces. Because of their redox and photophysical properties, artificial porphyrin systems have been designed for applications such as light-harvesting antennae, catalysts and sensors. Control of molecular orientation is required in order to construct practical devices, and in this project methods of assembling porphyrins on surfaces in well-defined patterns will be developed. Sophisticated methods will be used to characterise the films produced in these ways, in order to provide the information necessary to refine procedures and design new molecules suitable for advanced applications. Expected outcomes are new methods and architectures that can ultimately yield devices that act at the molecular level.Read moreRead less
Refinement of dynamic combinatorial chemistry as a drug discovery tool. Medicinal chemistry is constantly being challenged to develop efficient methodologies for the synthesis of compounds for drug discovery. Following completion of the Human Genome project, the cloning and expression of new proteins will proceed at an accelerated rate. In the absence of biochemical knowledge of the target protein there is a growing interest in techniques that expand the structural and biological diversity of co ....Refinement of dynamic combinatorial chemistry as a drug discovery tool. Medicinal chemistry is constantly being challenged to develop efficient methodologies for the synthesis of compounds for drug discovery. Following completion of the Human Genome project, the cloning and expression of new proteins will proceed at an accelerated rate. In the absence of biochemical knowledge of the target protein there is a growing interest in techniques that expand the structural and biological diversity of compound libraries. Dynamic combinatorial chemistry is an innovative technology with the capacity for supporting the shift from focussed to diverse compound libraries. This application seeks funding to refine dynamic combinatorial chemistry into an effective drug discovery tool.Read moreRead less
Developing high-flux ceramic membranes via in situ synthesis of metal oxide nanofibres for separations of biological substances. This project can deliver advanced technology for fabricating ceramic membranes and biological separation, which has considerable commercial prospects in the chemical, pharmaceutical, dairy, food and water industries. The new ceramic membrane and nanofibres are highly-valued end products of metal oxides, which are manufactured commercially on large scale in Australia. T ....Developing high-flux ceramic membranes via in situ synthesis of metal oxide nanofibres for separations of biological substances. This project can deliver advanced technology for fabricating ceramic membranes and biological separation, which has considerable commercial prospects in the chemical, pharmaceutical, dairy, food and water industries. The new ceramic membrane and nanofibres are highly-valued end products of metal oxides, which are manufactured commercially on large scale in Australia. The project could bring direct benefits to the existing industries, by fostering their growth into more value-added processes, and exporting highly-valued products abroad. Additionally, efficient ceramic membranes could offer solutions to the large-scale purification of biological substances and to the problems for providing clean drinking water.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0882787
Funder
Australian Research Council
Funding Amount
$390,000.00
Summary
An Integrated Raman Microscope and in Situ STM-TEM Analysis System. The imaging and analytical capabilities of SEM and chemical and structural characterisation afforded by Raman spectroscopy will be unique, allowing both rapid morphological observation and elemental analysis at the macro and nanoscale. The in-situ TEM holder will further assist through in-situ characterization of advanced materials at the nano-scale level. In combination, these instruments will underpin groundbreaking research i ....An Integrated Raman Microscope and in Situ STM-TEM Analysis System. The imaging and analytical capabilities of SEM and chemical and structural characterisation afforded by Raman spectroscopy will be unique, allowing both rapid morphological observation and elemental analysis at the macro and nanoscale. The in-situ TEM holder will further assist through in-situ characterization of advanced materials at the nano-scale level. In combination, these instruments will underpin groundbreaking research in diverse research fields developing new advanced nanomaterials and bio-nanomaterials with significant impact on many industries with great economical and environmental benefits. Read moreRead less
Formation, degradation and migration of a yet unidentified POP source. Australia has recently ratified the Stockholm Convention, targeting persistent organic pollutants (POPs) for global reduction and elimination. A significant gap exists, however, in understanding sources and pathways of POPs in Australia, and subtropical/tropical environments. Previous research has shown an extensive POP contamination in coastal Australia, and exposure of biota to elevated levels. The present study will evalua ....Formation, degradation and migration of a yet unidentified POP source. Australia has recently ratified the Stockholm Convention, targeting persistent organic pollutants (POPs) for global reduction and elimination. A significant gap exists, however, in understanding sources and pathways of POPs in Australia, and subtropical/tropical environments. Previous research has shown an extensive POP contamination in coastal Australia, and exposure of biota to elevated levels. The present study will evaluate the formation, degradation and migration of POPs, and their significance to Australia's past, present and future emissions. The outcomes will allow identification of sources, their prioritization for elimination and exposure prevention, and ultimately serve to protect the environment and human health in Australia.Read moreRead less
ARC Molecular and Materials Structure Research Network. The Network will build powerful e-Science resources for the structural sciences. Collaborative remote access will be developed for sophisticated instrumentation, including instruments planned for the Replacement Research Reactor and Australian Synchrotron. A structure database service with cross disciplinary content and versatile visualisation and analysis capabilities will further exemplify smart information use. The internet services will ....ARC Molecular and Materials Structure Research Network. The Network will build powerful e-Science resources for the structural sciences. Collaborative remote access will be developed for sophisticated instrumentation, including instruments planned for the Replacement Research Reactor and Australian Synchrotron. A structure database service with cross disciplinary content and versatile visualisation and analysis capabilities will further exemplify smart information use. The internet services will ultimately harness the Grid, enabling linkage into other national and international Grid systems. Encompassing physics, computer science, applied mathematics, chemistry and biochemistry, and catalysing interaction across these disciplines, the MMSN will impact all five National Research Priority 3 goals.Read moreRead less
The role of bush fires in the formation and fate of dioxin like chemicals in Australia. A global (POPs) treaty signed by more than 100 nations targets the reduction and elimination of dioxins, which are persistent, bioaccumlative and highly toxic to humans. Bushfires have been suggested as the major source of dioxins in Australia. Experimental data indicate bushfires may not represent the actual sources of dioxin. Our aim is to experimentally establish the levels of dioxins formed and re-emi ....The role of bush fires in the formation and fate of dioxin like chemicals in Australia. A global (POPs) treaty signed by more than 100 nations targets the reduction and elimination of dioxins, which are persistent, bioaccumlative and highly toxic to humans. Bushfires have been suggested as the major source of dioxins in Australia. Experimental data indicate bushfires may not represent the actual sources of dioxin. Our aim is to experimentally establish the levels of dioxins formed and re-emitted from bushfires in Australia. The results will assist to make informed decisions that lead to effective action for reducing dioxin contamination in Australia, fulfilling the treaty requirements and protecting the population and environment.
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Special Research Initiatives - Grant ID: SR0354691
Funder
Australian Research Council
Funding Amount
$30,000.00
Summary
A Grid Enabled Network for the Molecular and Materials Structure Sciences. The Molecular and Materials Structure Network will propel leading-edge Science by building powerful e-Science resources that will compel innovative collaborations of profound National benefit. Remote access will be developed for structure determination instruments, including the Research Reactor and Australian Synchrotron. A structure database with cross disciplinary content and powerful visualisation and analysis capabil ....A Grid Enabled Network for the Molecular and Materials Structure Sciences. The Molecular and Materials Structure Network will propel leading-edge Science by building powerful e-Science resources that will compel innovative collaborations of profound National benefit. Remote access will be developed for structure determination instruments, including the Research Reactor and Australian Synchrotron. A structure database with cross disciplinary content and powerful visualisation and analysis capabilities will exemplify "smart information use". Encompassing physics, computer science, chemistry and biochemistry, and catalysing interaction across these disciplines, the MMSN will impact all four National Research Priority 3 goals, and will be linked to other national and international Grids to become part of the emerging global Grid.Read moreRead less
Atmospheric fate and processes of semi-volatile organic compounds in tropical climates. The outcomes from this study will contribute fundamental and quantitative information for evaluation of the fate of semi-volatile organic compounds (SOCs) in tropical systems, including Australia's World Heritage ecosystems such as rainforest and the Great Barrier Reef. The study addresses key international knowledge gaps with respect to the influence of climate on SOC atmospheric fate. Australia's geographic ....Atmospheric fate and processes of semi-volatile organic compounds in tropical climates. The outcomes from this study will contribute fundamental and quantitative information for evaluation of the fate of semi-volatile organic compounds (SOCs) in tropical systems, including Australia's World Heritage ecosystems such as rainforest and the Great Barrier Reef. The study addresses key international knowledge gaps with respect to the influence of climate on SOC atmospheric fate. Australia's geographical location within the tropical belt provides an ideal opportunity for leading this field of research and contributes relevant data for its commitment under the Stockholm Convention.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989759
Funder
Australian Research Council
Funding Amount
$360,000.00
Summary
Australian Access to and Operation of Advanced Synchrotron Radiation Facilities at the Photon Factory. The primary national benefit of this application will be continued access by peer review for Australian scientists to the advanced synchrotron-radiation capabilities of the Australian National Beamline Facility and other complementary beamlines at the Photon Factory, Japan. This proposal is consistent with the National Research Priorities of An Environmentally Sustainable Australia, Promoting a ....Australian Access to and Operation of Advanced Synchrotron Radiation Facilities at the Photon Factory. The primary national benefit of this application will be continued access by peer review for Australian scientists to the advanced synchrotron-radiation capabilities of the Australian National Beamline Facility and other complementary beamlines at the Photon Factory, Japan. This proposal is consistent with the National Research Priorities of An Environmentally Sustainable Australia, Promoting and Maintaining Good Health and Frontier Technologies for Building and Transforming Australian Industries and will generate science to support and stimulate domestic industry, enhance the domestic knowledge base and international research profile, train students and future synchrotron scientists and foster domestic and international collaborations.Read moreRead less