Cyclophane Carbene Complexes as Catalysts: An Integrated Synthetic, Structural, and Mechanistic Approach. Metal-carbene complexes are emerging as efficient catalysts for chemical processes of immense importance to the pharmaceutical and fine chemicals industries. This project will build on the recent discovery of a family of complexes that exhibits the highest activity yet reported for metal-carbene catalysts in carbon-carbon bond-forming reactions. Insights into the ways the new catalysts work ....Cyclophane Carbene Complexes as Catalysts: An Integrated Synthetic, Structural, and Mechanistic Approach. Metal-carbene complexes are emerging as efficient catalysts for chemical processes of immense importance to the pharmaceutical and fine chemicals industries. This project will build on the recent discovery of a family of complexes that exhibits the highest activity yet reported for metal-carbene catalysts in carbon-carbon bond-forming reactions. Insights into the ways the new catalysts work will be gained through a combination of synthetic, mechanistic, and structural studies. This detailed investigation of structure/reactivity relationships will provide an understanding of why these catalyst are so efficient and hence give synthetic leads for the development of superior new catalysts suitable for industrial application.Read moreRead less
Monitoring and Modelling Hydrogeochemical Interactions with Groundwater : Implications for Mine Dewatering on Groundwater, River and Lake Chemistry. Alcoa operates a power station and brown coal mine at Anglesea in western Victoria. Following heavy rain in 2000 acidic water entered the Anglesea estuary causing precipitation of iron and aluminium flocs and fish kills. Estuary closure to tourism resulted. This project will identify the cause(s) of this phenomenon by modelling groundwater movement ....Monitoring and Modelling Hydrogeochemical Interactions with Groundwater : Implications for Mine Dewatering on Groundwater, River and Lake Chemistry. Alcoa operates a power station and brown coal mine at Anglesea in western Victoria. Following heavy rain in 2000 acidic water entered the Anglesea estuary causing precipitation of iron and aluminium flocs and fish kills. Estuary closure to tourism resulted. This project will identify the cause(s) of this phenomenon by modelling groundwater movement and studying geochemical processes. The resultant hydrogeochemical model will also be applied to simulating longer term water quality changes in the catchment arising from current mine dewatering operations and future rewatering following mine closure.
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Iron and Silica Co-precipitation from Industrial Zinc solutions. The aim of this research project is to gain a molecular level understanding of the physical processes that occur during the co-precipitation of iron and silica from electrolytic zinc liquors. The research program will be specifically focussed on systems in which similar concentrations of iron and silica are present in the liquor. Such systems are of interest to the industry partner as they represent the expected characteristics of ....Iron and Silica Co-precipitation from Industrial Zinc solutions. The aim of this research project is to gain a molecular level understanding of the physical processes that occur during the co-precipitation of iron and silica from electrolytic zinc liquors. The research program will be specifically focussed on systems in which similar concentrations of iron and silica are present in the liquor. Such systems are of interest to the industry partner as they represent the expected characteristics of future process requirements, but they are also of broader relevance to a range of mineral processing industries, as iron and silica occur as impurities in many mineral ores.Read moreRead less
Illuminating Molecular Electronic Rectification. This project aims to develop molecular rectifiers incorporating organometallic complexes for future electronics applications. The organometallic molecules will be an integral part of the electronic device to ameliorate the technological problems arising from miniaturisation of semiconductors. Expected outcomes are a new approach to molecular designs that provide a rectifying response in single molecules and large area molecular junctions. This sho ....Illuminating Molecular Electronic Rectification. This project aims to develop molecular rectifiers incorporating organometallic complexes for future electronics applications. The organometallic molecules will be an integral part of the electronic device to ameliorate the technological problems arising from miniaturisation of semiconductors. Expected outcomes are a new approach to molecular designs that provide a rectifying response in single molecules and large area molecular junctions. This should build manufacturing capacity in Australia and enhance international collaboration and reputation by addressing significant challenges in molecular electronics. Benefits arising include skilled researchers, internationalisation of Australian research and contributions to fundamental science.Read moreRead less
Accessing the therapeutic potential of carbon monoxide. Despite carbon monoxide being regarded as the ”silent killer”, it is now established that this molecule has beneficial effects for a number of conditions and pathologies, including inflammation, organ transplant rejection, bacterial infection, acute liver failure and as an aid in cancer therapies. This project proposes to explore the photochemistry of rhenium-containing species to discover more efficient carbon monoxide delivery agents. By ....Accessing the therapeutic potential of carbon monoxide. Despite carbon monoxide being regarded as the ”silent killer”, it is now established that this molecule has beneficial effects for a number of conditions and pathologies, including inflammation, organ transplant rejection, bacterial infection, acute liver failure and as an aid in cancer therapies. This project proposes to explore the photochemistry of rhenium-containing species to discover more efficient carbon monoxide delivery agents. By combining synthetic chemistry, photochemistry and cellular biology it is anticipated that this multidisciplinary research programme will advance the area of carbon monoxide therapies by preparing safer agents for the targeted and controlled delivery of carbon monoxide.Read moreRead less
Treating wastewater for potable reuse: removal of chemicals of concern using advanced oxidation processes. The project promotes Australia as a leader in water reuse technology and is of benefit to reuse schemes globally. Several major reuse schemes are planned for Australia and it is well recognised that robust science is needed for public confidence. Community perception is a serious barrier to potable reuse and the results from this project will provide essential and independent information fo ....Treating wastewater for potable reuse: removal of chemicals of concern using advanced oxidation processes. The project promotes Australia as a leader in water reuse technology and is of benefit to reuse schemes globally. Several major reuse schemes are planned for Australia and it is well recognised that robust science is needed for public confidence. Community perception is a serious barrier to potable reuse and the results from this project will provide essential and independent information for informed decision making. The oxidation processes proposed will improve the quality of both recycled water and waste brine, providing environmental and economic benefit. This is particularly significant for regional Australia, where there is substantial demand for both water reuse and cost-effective waste disposal in the absence of ocean discharge.Read moreRead less
Reducing glyphosate exposure from high use practices. This project aims to investigate methods of reducing occupational exposure to glyphosate, a ubiquitous pollutant of emerging concern. This will be achieved through developing new cost-effective analytical and sampling tools and refining methods for integrating human exposure (biomonitoring) data with surveillance data on the pathways of glyphosate exposure from high use. The project will generate new targeted knowledge on (sub) population-spe ....Reducing glyphosate exposure from high use practices. This project aims to investigate methods of reducing occupational exposure to glyphosate, a ubiquitous pollutant of emerging concern. This will be achieved through developing new cost-effective analytical and sampling tools and refining methods for integrating human exposure (biomonitoring) data with surveillance data on the pathways of glyphosate exposure from high use. The project will generate new targeted knowledge on (sub) population-specific chemical exposures in Australia, and globally. Such data are critical to inform public health and chemical regulation policy, and provide clear guidance aimed at reducing exposures, to assess the effectiveness of existing regulations, and provide a framework for implementing surveys in the future.Read moreRead less
Novel Technology for Improving Disinfection Outcomes in Regional and Remote Drinking Water Distribution Systems. Climate shifts have led to water supply shortages in many areas of Australia, both in rural and remote regions and in cities. To ease water shortages, transportation of water over long distances is becoming increasingly necessary. A major impediment to transfer of water through long mains is management of the disinfectant: most disinfectants decay too rapidly, leaving consumers at ris ....Novel Technology for Improving Disinfection Outcomes in Regional and Remote Drinking Water Distribution Systems. Climate shifts have led to water supply shortages in many areas of Australia, both in rural and remote regions and in cities. To ease water shortages, transportation of water over long distances is becoming increasingly necessary. A major impediment to transfer of water through long mains is management of the disinfectant: most disinfectants decay too rapidly, leaving consumers at risk of pathogen exposure. Chloramination, the most viable disinfection technology for this purpose, suffers from a process called nitrification which accelerates disinfectant decay. In this project, we are developing an innovative, patented process to prevent nitrification, which will allow safe and effective disinfection of water supplies in long pipelines.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0239647
Funder
Australian Research Council
Funding Amount
$290,000.00
Summary
Infrared chemical imaging and high temperature emission spectroscopy facility. Infrared spectroscopic imaging uses infrared radiation to analyse the chemical properties of microscopic samples in a fast and powerful manner. The images produced provide information about the different molecular chemistry at each pixel in the image. This is one of the latest and perhaps most important developments in vibrational spectroscopy, with wide applications in materials science, forensic science and the biol ....Infrared chemical imaging and high temperature emission spectroscopy facility. Infrared spectroscopic imaging uses infrared radiation to analyse the chemical properties of microscopic samples in a fast and powerful manner. The images produced provide information about the different molecular chemistry at each pixel in the image. This is one of the latest and perhaps most important developments in vibrational spectroscopy, with wide applications in materials science, forensic science and the biological sciences. It is an exceptional tool for the analysis of heterogeneous solids, whether these be seized drug samples, cancer cells, fibres left at a crime scene, layers of paint from a car or a Monet painting, or polymer blends.Read moreRead less
Correlative Imaging of Brain Lipids. This project aims to develop imaging tools and protocols for the detection of lipids in brain tissue and cells. This project expects to generate advanced methodologies to display specific lipid classes and their corresponding structures within tissues and cells, with the ability to be detected and correlated with multiple techniques, which represent a currently unavailable capacity. The expected outcomes of this project are improved opportunities to study lip ....Correlative Imaging of Brain Lipids. This project aims to develop imaging tools and protocols for the detection of lipids in brain tissue and cells. This project expects to generate advanced methodologies to display specific lipid classes and their corresponding structures within tissues and cells, with the ability to be detected and correlated with multiple techniques, which represent a currently unavailable capacity. The expected outcomes of this project are improved opportunities to study lipid biology at the cellular and sub-cellular level across a wide range of in vitro and in vivo models. The outcomes of this project should provide significant knowledge to tackle modern societal challenges in healthy ageing, brain pathologies and neurodegenerative diseases.Read moreRead less