Robust numerical solution of partial differential equations on petascale computer systems with applications to tsunami modelling and plasma physics. The project will apply new mathematical ideas to exploit the unprecedented computational resources provided by the next generation of high performance computers. The resulting techniques and software will form a key component for the science needed to understand the workings of complex dynamical systems, such as tsunamis and fusion reactors.
Innovative Technology for At-Scene Forensic Analysis using Microfluidics and Chemiluminescence. The major outcome of this project will be innovative reagents and strategies optimised for the detection of priority analytes such as drugs, explosives and chemical warfare agents. These will utilise a new technology platform based upon laboratory on a chip/microfluidics to enable the development of analytical methodologies suitable for use at crime scenes.This programme of research falls within a Nat ....Innovative Technology for At-Scene Forensic Analysis using Microfluidics and Chemiluminescence. The major outcome of this project will be innovative reagents and strategies optimised for the detection of priority analytes such as drugs, explosives and chemical warfare agents. These will utilise a new technology platform based upon laboratory on a chip/microfluidics to enable the development of analytical methodologies suitable for use at crime scenes.This programme of research falls within a National Research Priority namely 'Protecting Australia from terrorism and crime'. Through our current forensic science research collaboration the outcomes will build significantly on Australia's existing strengths in rapid detection using new analytical technologies.Read moreRead less
Designer Surfactants for Creation of Emulsion Properties. We propose new approaches to the design of surfactants for stabilising water in oil emulsions. New block copolymer surfactants may be "tailored" for head group structure and a pre-chosen hydrophilic/lipophilic balance at the oil-water interface using the Australian developed RAFT polymer synthesis method and polymeric inorganic species. The proposers have an extensive background in these areas.
X-ray and neutron scattering techniques, de ....Designer Surfactants for Creation of Emulsion Properties. We propose new approaches to the design of surfactants for stabilising water in oil emulsions. New block copolymer surfactants may be "tailored" for head group structure and a pre-chosen hydrophilic/lipophilic balance at the oil-water interface using the Australian developed RAFT polymer synthesis method and polymeric inorganic species. The proposers have an extensive background in these areas.
X-ray and neutron scattering techniques, developed by us, allow the interfacial structure of the surfactant to be found and the intellectual "loop" closed in the design process. Preliminary screening will be done using the surface balance and bulk emulsion synthesis.Read moreRead less
High Internal Phase Emulsions - Structure and Rheology Control. Our first SPIRT Grant with ORICA Australia Ltd has successfully identified nanostructures in high internal phase emulsions which confer useful stability and robustness on these industrially important systems. The aim now is to ramify those discoveries both scientifically and technologically in the design of emulsion structure using our, now established, techniques. In particular, the objective is to control both nanoscale and mes ....High Internal Phase Emulsions - Structure and Rheology Control. Our first SPIRT Grant with ORICA Australia Ltd has successfully identified nanostructures in high internal phase emulsions which confer useful stability and robustness on these industrially important systems. The aim now is to ramify those discoveries both scientifically and technologically in the design of emulsion structure using our, now established, techniques. In particular, the objective is to control both nanoscale and mesoscale structure in emulsion formulation, as well as the rheology and stability of emulsion preparations. To do this we plan to use mixed surfactant systems and to study intersurfactant synergic effects on the structure and fluidity of the interfacial material. We believe that the proposed work is unique and that the outcomes will be scientifically novel and also valuable for Australian industry.Read moreRead less
Milk protein denaturation and stabilisation at surfaces. The Australian Dairy Industry, valued at $2.8 billion in 2003-4, is ranked third among rural industries in Australia. Australia exports over 50% of its annual milk production, contributing to 13% of world trade. Exports of dairy products are valued at $2.4 billion. In order for Australia to maintain this position, Australia needs to keep up with its major competitors by ensuring quality and consistency of dairy products is maintained, and ....Milk protein denaturation and stabilisation at surfaces. The Australian Dairy Industry, valued at $2.8 billion in 2003-4, is ranked third among rural industries in Australia. Australia exports over 50% of its annual milk production, contributing to 13% of world trade. Exports of dairy products are valued at $2.4 billion. In order for Australia to maintain this position, Australia needs to keep up with its major competitors by ensuring quality and consistency of dairy products is maintained, and by developing new applications and innovative products. The proposal expects to recruit an exceptional young Australian graduate - a former Rhodes Scholar from Oxford University.Read moreRead less
In-field sensors for the detection of illicit drugs. Presumptive field test kits for illicit drugs analysis are typically based on chemical spot tests that produce a coloured product. While relatively easy to apply, such test kits (containing wet chemicals) produce inconclusive colour changes lacking sensitivity, and selectivity requiring a subjective assessment by the examiner. Despite these limitations, these test kits are in widespread use and are routinely used. This study aims to develop s ....In-field sensors for the detection of illicit drugs. Presumptive field test kits for illicit drugs analysis are typically based on chemical spot tests that produce a coloured product. While relatively easy to apply, such test kits (containing wet chemicals) produce inconclusive colour changes lacking sensitivity, and selectivity requiring a subjective assessment by the examiner. Despite these limitations, these test kits are in widespread use and are routinely used. This study aims to develop specific in-field sensors for the detection and identification of illicit drugs. This would significantly enhance the ability of Forensic Services staff to confirm the identity of seized material. Increased specificity would provide valuable early advice to investigators regarding the nature of a seizure and would reduce the likelihood of false positive results. Increased sensitivity would permit the analysis of trace amounts of material from individuals or locations related to an illicit drug consignment.Read moreRead less
Innovative measurement and modelling of greenhouse fluxes at regional scales across Australia. Carbon dioxide accounts for around 60% of the enhanced greenhouse effect. This proposal aims to markedly improve knowledge of the exchange of carbon, mostly as CO2, between atmospheric, ocean and land-based reservoirs in the Australian region. This will be achieved through a suite of measurements using innovative technologies: satellite and ground based remote sensing as well in situ measurements at ....Innovative measurement and modelling of greenhouse fluxes at regional scales across Australia. Carbon dioxide accounts for around 60% of the enhanced greenhouse effect. This proposal aims to markedly improve knowledge of the exchange of carbon, mostly as CO2, between atmospheric, ocean and land-based reservoirs in the Australian region. This will be achieved through a suite of measurements using innovative technologies: satellite and ground based remote sensing as well in situ measurements at Darwin and on the Ghan railway from Darwin to Adelaide. The measurements will be used to constrain inverse models of the carbon cycle and significantly reduce uncertainties in regional carbon source estimates. These estimates will in turn be compared to the Australian National Greenhouse Gas Inventory for comparison and verification.Read moreRead less
Synthetic compounds to specifically activate or inhibit ryanodine receptor calcium ion channels. The aim of the project is develop synthetic compounds that specifically and reversibly activate or inhibit ryanodine receptor calcium release channels, and will thus increase or reduce the force developed by skeletal muscle and the heart. The compounds will be useful in biomedical and veterinary sciences and in the livestock industry. Some of the compounds that are not effective on mammalian ryan ....Synthetic compounds to specifically activate or inhibit ryanodine receptor calcium ion channels. The aim of the project is develop synthetic compounds that specifically and reversibly activate or inhibit ryanodine receptor calcium release channels, and will thus increase or reduce the force developed by skeletal muscle and the heart. The compounds will be useful in biomedical and veterinary sciences and in the livestock industry. Some of the compounds that are not effective on mammalian ryandine receptor isoforms might interact with insect channels and provide a template for a new class of insecticides. The compounds will be based on naturally occurring peptides which specifically and reversibly modulate mammalian calcium channels.Read moreRead less
Characterisation of nanobubbles. Surprisingly, nano-sized bubbles have recently been found to exist in aqueous solutions. Classical theory tells us they should rapidly dissolve, yet they are stable for several days, a phenomenon which has only recently been explained. Despite this, nanobubbles are already used in cleaning processes and appear to have significant health benefits. They are being investigated in treatments for asthma and neurodegenerative diseases. In collaboration with a pharmaceu ....Characterisation of nanobubbles. Surprisingly, nano-sized bubbles have recently been found to exist in aqueous solutions. Classical theory tells us they should rapidly dissolve, yet they are stable for several days, a phenomenon which has only recently been explained. Despite this, nanobubbles are already used in cleaning processes and appear to have significant health benefits. They are being investigated in treatments for asthma and neurodegenerative diseases. In collaboration with a pharmaceutical company, the best means to produce and characterise nanobubbles will be investigated, as well as the conditions governing their stability. The project also aims to determine how the nanobubbles interact with surfaces in order to better control their properties and achieve a better understanding of these bubbles.Read moreRead less
Innovative platforms for further enhancing security and durability of the Australian Polymer Banknote and other security documents. The polymer banknote is a symbol of world-leading Australian innovation and prosperity. The utility, durability and security of our banknotes underpins consumer confidence, economic stability and national security. Events of recent years, and opportunities and threats from rapid global information flow heighten the need to enhance and renew the many security feature ....Innovative platforms for further enhancing security and durability of the Australian Polymer Banknote and other security documents. The polymer banknote is a symbol of world-leading Australian innovation and prosperity. The utility, durability and security of our banknotes underpins consumer confidence, economic stability and national security. Events of recent years, and opportunities and threats from rapid global information flow heighten the need to enhance and renew the many security features incorporated in our currency. The novel, cost-effective security-feature technologies to be developed in this project will also contribute to increasing the substantial polymer banknote export market, enable further expansion into other, even more demanding, security documents such as passports, and provide a needed boost to our domestic manufacturing industries.Read moreRead less