Developing a novel carbon negative fertiliser . Food security is vital to support our growing population. However, our increasing reliance on intensive farming systems necessitates increased fertiliser use, leading to increased water pollution and soil degradation - threatening both the Australian environment and food security. Increasing carbon storage capacity by soil and decreasing fertiliser use are two of the primary pathways for restoring the bio-support capacity of soils and reducing farm ....Developing a novel carbon negative fertiliser . Food security is vital to support our growing population. However, our increasing reliance on intensive farming systems necessitates increased fertiliser use, leading to increased water pollution and soil degradation - threatening both the Australian environment and food security. Increasing carbon storage capacity by soil and decreasing fertiliser use are two of the primary pathways for restoring the bio-support capacity of soils and reducing farming footprints. This innovative and first-of-its-kind project aims to develop a cost-effective, carbon negative fertiliser that reduces fertiliser inputs and increases soil carbon storageRead moreRead less
Environmental controls over Fe availability and transport in a forested coastal catchment. Iron is one of a number of elements that are mobilised in catchments, have recognised detrimental impacts to marine settings and are known to be nutrients for toxic cyanobacteria blooms. Knowledge of controls over distribution of Fe is important in catchment management and for sustainable forestry. The total catchment approach will result in an understanding of release and transport of Fe, and other heav ....Environmental controls over Fe availability and transport in a forested coastal catchment. Iron is one of a number of elements that are mobilised in catchments, have recognised detrimental impacts to marine settings and are known to be nutrients for toxic cyanobacteria blooms. Knowledge of controls over distribution of Fe is important in catchment management and for sustainable forestry. The total catchment approach will result in an understanding of release and transport of Fe, and other heavy metals. The outcomes of the study will enable useful comparison to coastal plantations elsewhere in Australia, and overseas. Determination of the relationship to rainfall and hydrological processes will enhance these comparisons plus consideration of climatic change.
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Finding lost dust storms: re-evaluation of the last 20 years of meteorological records to advance wind erosion mapping in Australia. The Dust Event Database (DEDB) at Griffith University is the only long term (1960 - present) record of wind erosion in Australia. It is used in many studies of the impact of dust on the terrestrial, atmospheric and marine environments as well as in studies of urban and regional air pollution and environmental health. Through this project, the revision of the DEDB w ....Finding lost dust storms: re-evaluation of the last 20 years of meteorological records to advance wind erosion mapping in Australia. The Dust Event Database (DEDB) at Griffith University is the only long term (1960 - present) record of wind erosion in Australia. It is used in many studies of the impact of dust on the terrestrial, atmospheric and marine environments as well as in studies of urban and regional air pollution and environmental health. Through this project, the revision of the DEDB will provide new knowledge on these impacts of wind erosion processes and will inform environmental policy through its contributions to the Caring for Our Country Program, the national State of the Environment, and the Australian Centre for Rangeland Information Systems.Read moreRead less
Elucidating structure and function of activation-associated secreted proteins (ASPs) in blood-feeding hookworms – toward new methods of control. The national/community benefits are: (1) to develop a long-term, high quality scientific and technological program contributing to national objectives, including the maintenance of a strong capability in basic research, the development of new scientific concepts and the enhancement of international collaborative links; (2) to strengthen the links betwee ....Elucidating structure and function of activation-associated secreted proteins (ASPs) in blood-feeding hookworms – toward new methods of control. The national/community benefits are: (1) to develop a long-term, high quality scientific and technological program contributing to national objectives, including the maintenance of a strong capability in basic research, the development of new scientific concepts and the enhancement of international collaborative links; (2) to strengthen the links between basic and applied research; (3) to develop excellence in research by promoting collaborative research, resulting in a more efficient use of resources in a national and international context; (4) to enhance the skills-base in biology and biotechnology; (5) to substantially increase global visibility through quality research, leading to an increased investment in Australian science.Read moreRead less
QUANTIFICATION OF INTERACTIONS DURING THE DISPERSION OF CORONA IONS AND AIRBORNE PARTICLES NEAR POWER LINES. Currently there is no method for quantification of concentration and dispersion of charged aerosols near high voltage power lines (HVPLs). However, hypothesis have been presented, but not yet proven scientifically, that residents of houses close to combustion sources such as highways or industrial plants and HVPLs may be subjected to health risk due to inhalation of charged aerosols. The ....QUANTIFICATION OF INTERACTIONS DURING THE DISPERSION OF CORONA IONS AND AIRBORNE PARTICLES NEAR POWER LINES. Currently there is no method for quantification of concentration and dispersion of charged aerosols near high voltage power lines (HVPLs). However, hypothesis have been presented, but not yet proven scientifically, that residents of houses close to combustion sources such as highways or industrial plants and HVPLs may be subjected to health risk due to inhalation of charged aerosols. The outcome of this project will be a model for quantitative assessment of the processes occurring during the transport and dispersion of corona ions and combustion aerosol, which will be a tool for predictive risk assessment and informed management of public resources in relation to power line design and maintenance.Read moreRead less
Translating pharmacokinetic and pharmacodynamic data to better design new drugs for the treatment of Trypanosoma cruzi infection. New drugs to treat T. cruzi infection are urgently needed, however their design has been hampered by an incomplete understanding of complex host-parasite interactions, inadequate in vitro and in vivo tools to rigorously define activity during drug discovery, and a poor appreciation of concentration/effect relationships. This project aims to develop new and much needed ....Translating pharmacokinetic and pharmacodynamic data to better design new drugs for the treatment of Trypanosoma cruzi infection. New drugs to treat T. cruzi infection are urgently needed, however their design has been hampered by an incomplete understanding of complex host-parasite interactions, inadequate in vitro and in vivo tools to rigorously define activity during drug discovery, and a poor appreciation of concentration/effect relationships. This project aims to develop new and much needed in vitro methods to better define the kinetic and dynamic activity of new drug candidates, and will provide a rational basis for translating this information into lengthy animal models of T. cruzi infection. The outcome aims to be rationally designed drug candidates that are available in a shorter period of time and are suitable for further development.Read moreRead less
The early communicative environment prior to and following cochlear implants: impact on children's early communicative and cognitive development. This research with children with cochlear implants will examine the effect on language development of being in an oral environment or one that also includes sign language. The outcomes will provide information for parents and professionals enabling informed decision about the management of the children to promote the best possible outcomes.
Oxytocin receptor PET ligands: imaging the love receptor’s engagement. This project aims to develop a positron emission tomography (PET) ligand for the oxytocin receptor. This novel platform is significant as it will allow the scientific community to answer questions about the role of the oxytocin receptor in the important process of social behaviour which underlies quality of life. This knowledge gap has remained unanswered for decades due to the lack of specific techniques to measure oxytocin ....Oxytocin receptor PET ligands: imaging the love receptor’s engagement. This project aims to develop a positron emission tomography (PET) ligand for the oxytocin receptor. This novel platform is significant as it will allow the scientific community to answer questions about the role of the oxytocin receptor in the important process of social behaviour which underlies quality of life. This knowledge gap has remained unanswered for decades due to the lack of specific techniques to measure oxytocin receptor engagement. It is also significant as it will equip Australian startup Kinoxis Therapeutics to progress their molecules to market, a process enabled by measuring oxytocin receptor engagement. Our dual expertise on the oxytocin receptor and PET ligand development uniquely situate us to generate this technology.Read moreRead less
Targeting virulence of Pseudomonas aeruginosa by inhibiting oxidative protein folding. Our research will lead to the development of compounds with a novel anti-virulence/antibacterial mode of action for further drug development.
Mapping the dark matter with early type galaxies. Unidentified dark matter outweighs luminous matter (stars, gas, and galaxies) by several times and is detected by its gravitational effects in the Universe. The Six Degree Field Galaxy Survey is now complete and this project will prepare a larger survey, which will put the team clearly in the lead in understanding the distribution of dark matter.