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Australasian Cerebral Palsy Clinical Trials Network (AusCP-CTN): Optimising Interventions And Effective Services For Children With Cerebral Palsy
Funder
National Health and Medical Research Council
Funding Amount
$2,499,287.00
Summary
Cerebral Palsy (CP) is common and disability can be progressive so the heathcare burden is immense (0.14% GDP). Our Clinical trials network will improve early detection and develop new interventions to improve physical, cognitive and health outcomes for children with CP and their families. Recruitment from the national CP Register will address clinically important questions and test implementation of effective treatments. New Clinical Practice Guidelines will ensure translation internationally.
The Role Of The Zinc Finger Transcriptional Repressor Znf238 During Nerve Cell Maturation
Funder
National Health and Medical Research Council
Funding Amount
$394,264.00
Summary
Proper foetal brain assembly is critical for brain function, but the underlying genetic mechanisms remain poorly defined. In this study, I will investigate a family of proteins that “turn on” neural gene expression in combination with another protein that “turns off” their expression during nerve cell development. Understanding this novel on/off mechanism for controlling gene expression in newborn nerve cells will further our understanding of how the brain is assembled.
Social, Environmental and Economic Sustainability in the Context of Melanesian Mining Projects. This is an interdisciplinary study of Melanesian understandings of socio-economic and environmental sustainability in the context of mining projects. It entails research into traditional ecological knowledge and assessment of ways that local understandings and expectations compromise programs based on Western scientific principles. It will examine local ideas about land use and food security, and the ....Social, Environmental and Economic Sustainability in the Context of Melanesian Mining Projects. This is an interdisciplinary study of Melanesian understandings of socio-economic and environmental sustainability in the context of mining projects. It entails research into traditional ecological knowledge and assessment of ways that local understandings and expectations compromise programs based on Western scientific principles. It will examine local ideas about land use and food security, and the social and cultural factors that determine responses to impacts of mining projects. The project will involve collaborative, interdisciplinary research, integrating social and cultural analysis and environmental and agrarian studies. It will contribute to current debates on environmentalism, mining impact and sustainable development.Read moreRead less
The costs of youth homelessness in Australia. This three-year research project will provide a detailed picture of the cost of youth homelessness in Australia, the use of services by young homeless people and the costs and benefits of providing support services to young homeless people. The study will extend the evidence base on the cost-effectiveness of programs attempting to alleviate youth homelessness, and enable Australian governments, community groups and agencies involved in the provision ....The costs of youth homelessness in Australia. This three-year research project will provide a detailed picture of the cost of youth homelessness in Australia, the use of services by young homeless people and the costs and benefits of providing support services to young homeless people. The study will extend the evidence base on the cost-effectiveness of programs attempting to alleviate youth homelessness, and enable Australian governments, community groups and agencies involved in the provision of support services to homeless youth to understand better the pathways followed by young homeless people and the impact of service provision on the lives of young homeless people.Read moreRead less
Engaging the over 50s to ensure the sustainability of our blood supply. Australia faces blood shortages as our population ages and demand for blood-product derived treatments increase. Donors aged over 50 donate more regularly with fewer adverse events than younger donors, yet comprise under 24% of blood donors. This multi-method project aims to investigate how those aged over 50 understand and engage with blood donation in the context of ageing, and how their involvement can be managed to maint ....Engaging the over 50s to ensure the sustainability of our blood supply. Australia faces blood shortages as our population ages and demand for blood-product derived treatments increase. Donors aged over 50 donate more regularly with fewer adverse events than younger donors, yet comprise under 24% of blood donors. This multi-method project aims to investigate how those aged over 50 understand and engage with blood donation in the context of ageing, and how their involvement can be managed to maintain psychosocial wellbeing. This project expects to generate new knowledge in recruiting, retaining, and deferring older blood donors. Expected outcomes include tailored, validated resources that may significantly benefit Australia by effectively engaging older adults to ensure the sustainability of the blood supply.Read moreRead less
ARC Centre of Excellence for Children and Families over the Life Course. The 2020 ARC Centre of Excellence for Children and Families over the Life Course (LCC2020) aims to deliver transformative research and translation to break the cycle of deep and persistent disadvantage for Australians. Critically, LCC2020 will tackle disadvantage in specific context to understand how people negotiate it daily in real places, and how best to design policies and programs that support improved life pathways. B ....ARC Centre of Excellence for Children and Families over the Life Course. The 2020 ARC Centre of Excellence for Children and Families over the Life Course (LCC2020) aims to deliver transformative research and translation to break the cycle of deep and persistent disadvantage for Australians. Critically, LCC2020 will tackle disadvantage in specific context to understand how people negotiate it daily in real places, and how best to design policies and programs that support improved life pathways. By understanding life course contexts much more finely and using new methods and better data to personalise responses to disadvantage, LCC2020 will deliver the evidence, infrastructure, capacity and partnerships to reduce disadvantage and better equip Australian children and families for emerging challenges. Read moreRead less
Early Career Industry Fellowships - Grant ID: IE230100672
Funder
Australian Research Council
Funding Amount
$470,337.00
Summary
Measuring real-time mental workload to improve our Defence capability. This project aims to develop a novel platform for measuring real-time variation in the cognitive workload of humans working with advanced Defence technologies. The project expects to combine innovative statistical techniques with cutting-edge psychological and neuroscience developments to measure and process workload-related brain activity in real-time. Expected outcomes of the project include an enhanced capacity to measure ....Measuring real-time mental workload to improve our Defence capability. This project aims to develop a novel platform for measuring real-time variation in the cognitive workload of humans working with advanced Defence technologies. The project expects to combine innovative statistical techniques with cutting-edge psychological and neuroscience developments to measure and process workload-related brain activity in real-time. Expected outcomes of the project include an enhanced capacity to measure and respond to cognitive workload in the field. This should provide significant benefits such as enhanced performance and safety outcomes, which will provide a strategic advantage to the Australian Defence Force by facilitating the development of advanced technologies that respond to the capabilities of the human user.Read moreRead less
Enhancing outcomes for young people in out-of-home care who self-place. This project aims to enhance the safety and well-being of young people in out-of-home care who leave formal placements to stay in unapproved locations. The significance lies in the development of new knowledge with this group of young people about their needs and of factors shaping effective responses to them. Expected outcomes include the generation of policies and practices to reduce the drivers of young people leaving a ....Enhancing outcomes for young people in out-of-home care who self-place. This project aims to enhance the safety and well-being of young people in out-of-home care who leave formal placements to stay in unapproved locations. The significance lies in the development of new knowledge with this group of young people about their needs and of factors shaping effective responses to them. Expected outcomes include the generation of policies and practices to reduce the drivers of young people leaving approved placements and to address the support and protective needs of young people when staying in unapproved locations. The benefits include improved social and economic inclusion of young people in out-of-home care and reduced socio-economic burdens on health and justice systems associated with placement breakdown. Read moreRead less
Lived experiences of treatment for hepatitis C in Australia. This project aims to support uptake of new hepatitis C treatments. With the introduction of new treatments in 2016, the Australian Government adopted the WHO’s goal of eliminating the disease by 2030. While early treatment rates were high, they have since plateaued, with stigma and poor information considered key obstacles. This project will generate new knowledge on treatment decisions and experiences, using a proven qualitative metho ....Lived experiences of treatment for hepatitis C in Australia. This project aims to support uptake of new hepatitis C treatments. With the introduction of new treatments in 2016, the Australian Government adopted the WHO’s goal of eliminating the disease by 2030. While early treatment rates were high, they have since plateaued, with stigma and poor information considered key obstacles. This project will generate new knowledge on treatment decisions and experiences, using a proven qualitative methodology. In doing so, it will produce a website covering personal experiences of treatment, issues in treatment decision-making, and advice on enhancing life on treatment and after. It will tackle hepatitis C-related stigma, and inform and benefit potential treatment users, families and relevant professionals.
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Transitioning from out-of-home care: a longitudinal population-based study. This project aims to use a population-based method to examine the pathways of young people in, and transitioning from, out-of-home care in Western Australia. Young people in, and transitioning out of, out-of-home care experience many challenges. Care leavers, including a disproportionate number of Aboriginal young people, experience adverse outcomes across a range of domains leading to high social and economic costs for ....Transitioning from out-of-home care: a longitudinal population-based study. This project aims to use a population-based method to examine the pathways of young people in, and transitioning from, out-of-home care in Western Australia. Young people in, and transitioning out of, out-of-home care experience many challenges. Care leavers, including a disproportionate number of Aboriginal young people, experience adverse outcomes across a range of domains leading to high social and economic costs for the Australian community. The findings from the population-based data, together with an in-depth understanding of their lived experiences will identify a best practice model for improving their transition from care experiences to facilitate improved outcomes.Read moreRead less