Spatiotemporal signatures of learning in brain reward systems. Learning to strengthen behaviours that secure resources and warrant survival is one of the primary functions of the brain. This Project seeks to establish the rules that govern the integration of learning in brain reward systems by studying how neuronal circuits change their molecular signatures as animals assimilate new knowledge. These studies will combine novel experimental designs to investigate learning with multidisciplinary me ....Spatiotemporal signatures of learning in brain reward systems. Learning to strengthen behaviours that secure resources and warrant survival is one of the primary functions of the brain. This Project seeks to establish the rules that govern the integration of learning in brain reward systems by studying how neuronal circuits change their molecular signatures as animals assimilate new knowledge. These studies will combine novel experimental designs to investigate learning with multidisciplinary methods for mapping, recording and functionalising teaching signals in behaving mice. The outcomes will create a significant shift in our understanding of the neural bases that underlie reward learning, and will critically expand the field by providing a new model of learning integration in brain systems.Read moreRead less
Mechanisms of memory integration in brain systems. Learning from our interactions with the environment is one of the brain’s most important functions, yet how and where this process takes place at the neural network level has proven difficult to establish. This Project seeks to investigate how major neuromodulatory signals in the brain coordinate the encoding of reward-based learning in large ensembles of neurons. These studies will combine novel behavioural paradigms with the most recent neuros ....Mechanisms of memory integration in brain systems. Learning from our interactions with the environment is one of the brain’s most important functions, yet how and where this process takes place at the neural network level has proven difficult to establish. This Project seeks to investigate how major neuromodulatory signals in the brain coordinate the encoding of reward-based learning in large ensembles of neurons. These studies will combine novel behavioural paradigms with the most recent neuroscience techniques for functional mapping and manipulation of specific neural circuits in behaving mice. The outcomes of this research will lead to a significant shift in our understanding of the mechanisms underpinning the integration of learning in brain systems and its implications for behaviour.Read moreRead less
Investigating voluntary and involuntary intergroup contact . Extensive research suggests that interactions between people of opposing groups - intergroup contact - reduce prejudices and improve social cohesion. Yet these benefits may not be realised if intergroup contact is actively avoided, passively received, or mandated. Drawing from social psychology and human geography, this project aims to establish the conditions under which voluntary contact occurs and how voluntary (vs. involuntary) int ....Investigating voluntary and involuntary intergroup contact . Extensive research suggests that interactions between people of opposing groups - intergroup contact - reduce prejudices and improve social cohesion. Yet these benefits may not be realised if intergroup contact is actively avoided, passively received, or mandated. Drawing from social psychology and human geography, this project aims to establish the conditions under which voluntary contact occurs and how voluntary (vs. involuntary) intergroup contact shapes diversity experiences and impacts social attitudes, trust, and civic participation. With data from multiple settings and participant populations, this project has the potential to inform interventions and policies that deliver harmonious, healthy and productive communities.Read moreRead less
How satiation control reward value and cue-induced appetitive behaviours. This proposal aims to identify mechanisms that control environment-driven food-seeking behaviours. It seeks to do so by using modern virally-mediated and basic behavioural as well as histological techniques in a transgenic rat to characterise novel hindbrain circuits that control these feeding behaviours. This is significant as environment-driven overeating is problematic yet underlying mechanisms are unclear. This project ....How satiation control reward value and cue-induced appetitive behaviours. This proposal aims to identify mechanisms that control environment-driven food-seeking behaviours. It seeks to do so by using modern virally-mediated and basic behavioural as well as histological techniques in a transgenic rat to characterise novel hindbrain circuits that control these feeding behaviours. This is significant as environment-driven overeating is problematic yet underlying mechanisms are unclear. This project expects to provide new knowledge on when, where and how hindbrain neurons control environment-driven food-seeking behaviours. This should provide benefits to the advancement of knowledge on the neural mechanisms of food-seeking and provide a basic science platform for future research on the study of feeding behaviours.
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Improving the Well-Being of Low Socioeconomic Status Students at University. This project aims to investigate a new approach to improving the mental well-being of university students from low socioeconomic status (SES) backgrounds. University students have a high risk of experiencing mental health problems, and students from low SES backgrounds have a particularly high risk. This project aims to investigate university-relevant Facebook groups as a method of improving the mental well-being of low ....Improving the Well-Being of Low Socioeconomic Status Students at University. This project aims to investigate a new approach to improving the mental well-being of university students from low socioeconomic status (SES) backgrounds. University students have a high risk of experiencing mental health problems, and students from low SES backgrounds have a particularly high risk. This project aims to investigate university-relevant Facebook groups as a method of improving the mental well-being of low SES students by improving their online social integration at university. Expected outcomes and benefits include a scalable, low-cost approach to reducing an SES inequality that costs Australia billions of dollars each year.Read moreRead less
Hippocampal regulation of goal-directed decision-making. The hippocampus is a part of the brain that is central to learning and memory yet little is known about its role in decision-making. It is the aim of this application to provide the first detailed, causal evidence of hippocampal regulation of decision-making. This is significant because many mental health disorders and dementias that involve decision-making deficits are characterised by hippocampal dysfunction, but any direct link between ....Hippocampal regulation of goal-directed decision-making. The hippocampus is a part of the brain that is central to learning and memory yet little is known about its role in decision-making. It is the aim of this application to provide the first detailed, causal evidence of hippocampal regulation of decision-making. This is significant because many mental health disorders and dementias that involve decision-making deficits are characterised by hippocampal dysfunction, but any direct link between these factors is unknown. The outcomes of the current grant will provide the first evidence of that link, thus providing deeper understanding of the neurophysiological mechanisms of these disorders, which could eventuate in the creation of more beneficial treatments. Read moreRead less
When, why, and how well do we regulate other people's emotions? This project aims to understand when and why people attempt to regulate others' emotions, and to evaluate which regulation processes are most effective. We will study regulation attempts as they occur over minutes, days, and months in interactions between romantic couples and between nurse co-workers. This project extends the study of emotion regulation to others’ emotions as well as one’s own. The major project output will be an ev ....When, why, and how well do we regulate other people's emotions? This project aims to understand when and why people attempt to regulate others' emotions, and to evaluate which regulation processes are most effective. We will study regulation attempts as they occur over minutes, days, and months in interactions between romantic couples and between nurse co-workers. This project extends the study of emotion regulation to others’ emotions as well as one’s own. The major project output will be an evidence-based theory of extrinsic regulation. Project benefits include applications of this new knowledge to programs and policies that reduce negative emotions and stress in healthcare workers and couples, reducing workplace burnout, on-the-job errors, relationship breakdown and their associated economic costs.Read moreRead less
Brain systems implicated in alcohol-related aggression. Alcohol has many adverse effects on social behaviour and emotion regulation. Aggressive behaviour is one of the most common social behaviours that intoxicated people display. Using neuroimaging and brain stimulation technology, this project aims to identify how alcohol disrupts brain networks implicated in anger and emotion regulation. Expected outcomes of this project include discovery of how the brain responds to social provocation, suppo ....Brain systems implicated in alcohol-related aggression. Alcohol has many adverse effects on social behaviour and emotion regulation. Aggressive behaviour is one of the most common social behaviours that intoxicated people display. Using neuroimaging and brain stimulation technology, this project aims to identify how alcohol disrupts brain networks implicated in anger and emotion regulation. Expected outcomes of this project include discovery of how the brain responds to social provocation, supports emotion regulation, and produces aggressive behaviour when intoxicated. Benefits include identifying how the intoxicated brain contributes to the millennia-old phenomenon of alcohol-related aggression and how brain stimulation may protect against aggression.Read moreRead less
Understanding secrecy in everyday life. This project aims to undertake the first systematic investigation of secrecy in everyday life. Secrecy is often vital in professional and personal life, but current scientific understanding of the costs and processes of secrecy is limited. This project proposes using innovative methodologies to estimate the psychological costs of secrecy and test an intervention to reduce these costs. Expected outcomes include developing theory, advancing methodology, and ....Understanding secrecy in everyday life. This project aims to undertake the first systematic investigation of secrecy in everyday life. Secrecy is often vital in professional and personal life, but current scientific understanding of the costs and processes of secrecy is limited. This project proposes using innovative methodologies to estimate the psychological costs of secrecy and test an intervention to reduce these costs. Expected outcomes include developing theory, advancing methodology, and building research capacity in supporting exceptional scholars. Significant benefits include educating community members about how to combat the harmful effects of secrecy.Read moreRead less
How inequalities affect attitudes and behaviours concerning sex and gender. This project addresses how economic inequalities—between and within the sexes—shape behaviour, gender sentiment, and violence both online and ‘in real life’. The research brings evolutionary understandings of sexual marketplaces together with the psychology of social behaviour, to shed new light on the origins of sexual conflict and harmful gender ideologies. This project integrates within-individual variation, careful e ....How inequalities affect attitudes and behaviours concerning sex and gender. This project addresses how economic inequalities—between and within the sexes—shape behaviour, gender sentiment, and violence both online and ‘in real life’. The research brings evolutionary understandings of sexual marketplaces together with the psychology of social behaviour, to shed new light on the origins of sexual conflict and harmful gender ideologies. This project integrates within-individual variation, careful experimental dissection of the sources of inequality, and the study of large-scale (among cities, among countries) patterns of behaviour on social media. A fuller understanding of how and why inequalities affect behaviour presents opportunities for improved social policy and responses to gendered violence and cyberhate.Read moreRead less