Improving Indigenous health and wellbeing over the family life course. Improving Indigenous health and wellbeing over the family life course. This project aims to reduce Indigenous health inequalities, a major social and economic problem, by improving the policy relevant evidence base on the determinants of Indigenous health and wellbeing. This project will compare the impact of the family life course on the health and wellbeing of Indigenous and non-Indigenous mothers and children. It will use ....Improving Indigenous health and wellbeing over the family life course. Improving Indigenous health and wellbeing over the family life course. This project aims to reduce Indigenous health inequalities, a major social and economic problem, by improving the policy relevant evidence base on the determinants of Indigenous health and wellbeing. This project will compare the impact of the family life course on the health and wellbeing of Indigenous and non-Indigenous mothers and children. It will use survey data that follows them over time to: 1) identify family structures that enhance or harm health and wellbeing, and; 2) track changes in health and wellbeing before, during and after family transitions (i.e. births, relationship changes). Anticipated results are better targeted policy interventions to reduce Indigenous health inequalities.Read moreRead less
Identifying genes that influence clinical course and susceptibility in multiple sclerosis. This project aims to identify the genetic basis of multiple sclerosis (MS), the most common neurologic disease in young Australian adults. MS urgently needs research to identify predisposition, aid early diagnosis and provide bona fide molecular targets for new therapies. This will benefit people with MS and those susceptible to it. Crucial new knowledge identified will benefit other major areas of MS rese ....Identifying genes that influence clinical course and susceptibility in multiple sclerosis. This project aims to identify the genetic basis of multiple sclerosis (MS), the most common neurologic disease in young Australian adults. MS urgently needs research to identify predisposition, aid early diagnosis and provide bona fide molecular targets for new therapies. This will benefit people with MS and those susceptible to it. Crucial new knowledge identified will benefit other major areas of MS research including epidemiology, immunology and neurobiology. Collaboration of 8 major Australian institutions is also important for this project and future studies. The team will have access to a new national MS GeneBank (platform) with samples from 2240 patients that should generate findings important to world-wide MS genetic knowledge.Read moreRead less
Special Research Initiatives - Grant ID: SR1101002
Funder
Australian Research Council
Funding Amount
$21,000,000.00
Summary
Stem Cells Australia. Despite progress in stem cell research, scientists do not understand how stem cells “decide” what to become. Stem Cells Australia will draw upon strengths within Australia’s premier stem cell research universities and institutes. This collaboration between leading bioengineering, nanotechnology, stem cell and advanced molecular analysis experts, will fast-track efforts to deliver a fundamental understanding of the mechanisms of stem cell regulation and differentiation, and ....Stem Cells Australia. Despite progress in stem cell research, scientists do not understand how stem cells “decide” what to become. Stem Cells Australia will draw upon strengths within Australia’s premier stem cell research universities and institutes. This collaboration between leading bioengineering, nanotechnology, stem cell and advanced molecular analysis experts, will fast-track efforts to deliver a fundamental understanding of the mechanisms of stem cell regulation and differentiation, and the ability to control and influence this process. Stem Cells Australia will deliver new methods for stem cell propagation and manipulation, new translational technologies for therapeutic applications, and will prepare Australia’s future stem cell scientific leaders.Read moreRead less
Big-Picture Bioethics: policy-making and liberal democracy. We live an era of rapid growth in biotechnology generating new and difficult ethical questions that need to be tackled by bioethicists and politicians. This project goes beyond typical approaches in bioethics to explore the "big picture": how policies are generated in ethically-contentious domains. It is important to examine how the values of different stakeholders are reflected in such processes to ensure that they are in accordance wi ....Big-Picture Bioethics: policy-making and liberal democracy. We live an era of rapid growth in biotechnology generating new and difficult ethical questions that need to be tackled by bioethicists and politicians. This project goes beyond typical approaches in bioethics to explore the "big picture": how policies are generated in ethically-contentious domains. It is important to examine how the values of different stakeholders are reflected in such processes to ensure that they are in accordance with Australia's commitment to fostering a multicultural, pluralistic, democratic society. This project will produce practical recommendations for refining public consultation in healthcare policy-making through an examination of three relevant contentious case studies in Australia with comparison to Canada.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0882701
Funder
Australian Research Council
Funding Amount
$300,000.00
Summary
Establishment of a confocal/multiphoton microscope for imaging of living systems. This facility will allow us to study the dynamic changes in living systems, from the smallest unicellular organisms in the ocean through to the sophisticated neural networks of the living brain. Not only will this imaging facility allow us to understand how living systems work, we will also be able to explore the dynamic changes that underlie human disease and injury.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE200100074
Funder
Australian Research Council
Funding Amount
$580,000.00
Summary
Data Co-operative Platform for Social Impact and Wellbeing. The Data Cooperative (Co-Op) Platform for Social Impact and Wellbeing aims to make data-driven research and decision-making in the social sciences more effective and efficient by developing infrastructure to support data integration and harmonisation of diverse data resources. Social research relies on a vast array of data types and sources, both open and confidential, making data analysis complex and time-consuming. This project will d ....Data Co-operative Platform for Social Impact and Wellbeing. The Data Cooperative (Co-Op) Platform for Social Impact and Wellbeing aims to make data-driven research and decision-making in the social sciences more effective and efficient by developing infrastructure to support data integration and harmonisation of diverse data resources. Social research relies on a vast array of data types and sources, both open and confidential, making data analysis complex and time-consuming. This project will drive innovation across a range of critical social issues that require integrated data for research and social innovation including healthcare, better outcomes for disadvantaged and vulnerable groups, resilient urban, rural and regional communities, and increasing our capacity to respond to climate change. Read moreRead less
Quantifying sea-level trends and extremes along Australia's coastal margin. Multi-decadal changes in sea-level, and sea-level extremes, cannot be well quantified along most global coastlines, including Australia's, because the high spatial variability of sea-level is under-sampled by the sparse set of long, high quality tide gauge records. Satellite altimetry provides an alternative data source with greater spatial sampling, yet experiences contamination from land within tens of kilometres from ....Quantifying sea-level trends and extremes along Australia's coastal margin. Multi-decadal changes in sea-level, and sea-level extremes, cannot be well quantified along most global coastlines, including Australia's, because the high spatial variability of sea-level is under-sampled by the sparse set of long, high quality tide gauge records. Satellite altimetry provides an alternative data source with greater spatial sampling, yet experiences contamination from land within tens of kilometres from the coast and also suffers from regionally correlated biases. This project proposes to address these problems through re-tracking radar altimetry waveforms to derive new data in the coastal margin, enabling the production of new inferences on sea-level change and extremes at dramatically improved spatial resolution around Australia.Read moreRead less
Unraveling ocean mixing and air-sea forcing along the Indo-Pacific exchange. This project aims to collect unprecedented observations and develop high resolution model simulations to examine changes in the Indonesian Throughflow (ITF) north of Australia. This project expects to develop new knowledge of ocean-atmosphere interactions along the path of the ITF from the Pacific to the Indian Ocean, which are the powerhouse that drives changes in winds and rainfall around Australia and the entire Indo ....Unraveling ocean mixing and air-sea forcing along the Indo-Pacific exchange. This project aims to collect unprecedented observations and develop high resolution model simulations to examine changes in the Indonesian Throughflow (ITF) north of Australia. This project expects to develop new knowledge of ocean-atmosphere interactions along the path of the ITF from the Pacific to the Indian Ocean, which are the powerhouse that drives changes in winds and rainfall around Australia and the entire Indo-Pacific region. Expected outcomes include a 1000-fold increase in the observations of mixing in the Indonesian seas and new understanding of the ocean-atmosphere processes that control water property change along the ITF. This should lead to strong improvement in the skill of climate forecast models in the Australian region.Read moreRead less
Analysing the protective role of platelets during malaria infection. Platelets protect the host during malarial infection. This project aims to study how platelets kill the malaria parasite by investigating the role of host molecules and their potential as novel antimalarial agents. The role of platelets in the pathogenesis of cerebral malaria syndrome will also be investigated.