Injecting Drug Users: Social Networks And Molecular Epidemiology Of The Hepatitis C Virus
Funder
National Health and Medical Research Council
Funding Amount
$543,868.00
Summary
The hepatitis C virus (HCV) continues to spread among injecting drug users (IDUs) in Australia at a very high rate, despite success in preventing the spread of HIV in the same groups; the complete reasons for this remain unclear. There is an urgent need for the HCV epidemic among IDUs to be contained. To do so, we must better understand the ways in which it is spreading among IDUs. Much is known about risk behaviours of individual IDUs and how they contribute to HCV transmission; much less is kn ....The hepatitis C virus (HCV) continues to spread among injecting drug users (IDUs) in Australia at a very high rate, despite success in preventing the spread of HIV in the same groups; the complete reasons for this remain unclear. There is an urgent need for the HCV epidemic among IDUs to be contained. To do so, we must better understand the ways in which it is spreading among IDUs. Much is known about risk behaviours of individual IDUs and how they contribute to HCV transmission; much less is known about how these behaviours are modified by the influence of the IDUs peer group, especially their immediate and intimate social networks. Despite its importance in influencing attitudes and behaviours, and therefore HCV transmission, this has never been studied in Australia, nor, in relation to HCV, in the world. We hope that by studying social and risk networks of IDUs we shall discover new ways in which control of the HCV epidemic can be achieved in Australia. We intend to do this among two groups of young IDUs, one of Vietnamese ethnicity, located in the one suburb of Melbourne. By using field techniques for gathering information (ethnography), and sophisticated analytic techniques to understand how these networks are formed and influence behaviours, we hope to be able to identify interventions which work at the level of the social group rather than the individual in bringing about the behaviour change necessary to prevent HCV transmission. To ensure that the risk networks we describe are as influential as they appear, and to discover more about the variability of HCV, we will also be investigating the relationship between the various strains of HCV in members of the IDU networks, particularly as another measure of the connectedness of networks and network members. This will be done using sophisticated genetic analysis of the HCV obtained from network members by blood test.Read moreRead less
Understanding The Dynamics Of The Medical Workforce To Improve Population Health And Equity Of Access: The Australian Lo
Funder
National Health and Medical Research Council
Funding Amount
$2,278,544.00
Summary
The health workforce is now a key area of government policy. The ageing of the medical workforce, combined with more women entering medicine and changes in doctors preferences over their work-life balance, are all likely to have important effects on the ability of health care system to provide good quality and accessible health care. However, there is little knowledge or understanding of how and why doctors make decisions on how many hours they work, their location of work, including working in ....The health workforce is now a key area of government policy. The ageing of the medical workforce, combined with more women entering medicine and changes in doctors preferences over their work-life balance, are all likely to have important effects on the ability of health care system to provide good quality and accessible health care. However, there is little knowledge or understanding of how and why doctors make decisions on how many hours they work, their location of work, including working in rural and remote areas, and decisions to leave the medical workforce and retire. These decisions have important effects on the population�s access to health care and therefore on their health status and quality of care received. The aim of this research is to examine those factors influencing doctors� labour supply decisions through the establishment of the Australian Longitudinal Survey of Doctors (ALSD). The survey will track 5,500 doctors over an initial four year period. The research will provide a rigorous analysis of medical workforce decisions that underpin workforce distribution and the working patterns of doctors. The survey will be used to evaluate and simulate policy changes and provide important evidence to support future policy developments.Read moreRead less
Modelling The Economics Of The Australian Health Care System For Policy Analysis
Funder
National Health and Medical Research Council
Funding Amount
$3,500,000.00
Summary
The program will build a suite of economic models capable of providing timely relevant analysis of almost any major health policy option or issue, providing expertise in government and academia to use the kind of sophisticated quantitative tools of analysis common in sectors of the economy of an equivalent size to health. Through a PhD and postdoctoral program, it will increase capacity in quantitative health economics in Australia to answer key questions in health services, health promotion and ....The program will build a suite of economic models capable of providing timely relevant analysis of almost any major health policy option or issue, providing expertise in government and academia to use the kind of sophisticated quantitative tools of analysis common in sectors of the economy of an equivalent size to health. Through a PhD and postdoctoral program, it will increase capacity in quantitative health economics in Australia to answer key questions in health services, health promotion and illness prevention, developed with partners in government, clinicians and industry.Read moreRead less
Statistical Methods And Algorithms For Analysis Of High-throughput Genetics And Genomics Platforms
Funder
National Health and Medical Research Council
Funding Amount
$1,557,500.00
Summary
Through rapid advances in high-throughput -omics technologies, the number of phenotypes and the number of genotypes in gene mapping studies are or will be orders of magnitudes larger than in previous studies. Current algorithms and analysis methods have not kept up with the speed of data collection, nor has the training of qualified researchers. We will develop quantitative trait loci (fine) mapping analysis methods and bioinformatics algorithms and train (post)graduates in these research areas.
The Development Of A Model Of Care For Haematology And Palliative Care
Funder
National Health and Medical Research Council
Funding Amount
$149,044.00
Summary
The aim of the multi-site partnership is to build on foundational work initiated by NH and MRC to establish a model for end-of-life care in adult Haematology and palliative care. Preliminary work indicates this diagnostic category does NOT presently receive palliative care. Consumer research indicates that end-of-life care in haematology is associated with the distress of escalating technology, post-traumatic stress and spiritual pain. This study seeks to address this situation by building on th ....The aim of the multi-site partnership is to build on foundational work initiated by NH and MRC to establish a model for end-of-life care in adult Haematology and palliative care. Preliminary work indicates this diagnostic category does NOT presently receive palliative care. Consumer research indicates that end-of-life care in haematology is associated with the distress of escalating technology, post-traumatic stress and spiritual pain. This study seeks to address this situation by building on the prior consumer researcher to develop a model of care through a multi-disciplinary consultation with haematology professionals and consumers.Read moreRead less
Renal Dialysis Abatement: Decision-making & Social Impact Of The Transition To Terminal Care
Funder
National Health and Medical Research Council
Funding Amount
$100,000.00
Summary
A study of the impact on patients and their families of the decision to stop kidney machine dialysis, and the transition to terminal care, either in an in-patient hospice-palliative care unit or domicillary service. The study will employ a combination of quantitative demographic and qualitative social science methodologies. There will be a special focus on the decision-making process, given that a dialysis cessation decision will usually lead to death within a few weeks.
Cost Effectiveness Of Glucosamine Sulphate For Knee Arthritis (COGS)
Funder
National Health and Medical Research Council
Funding Amount
$448,791.00
Summary
A clinical trial, conducted in general practice, randomising 340 patients with symptomatic knee osteoarthritis to glucosamine sulphate or matching placebo tablets for 9 months. The main study outcomes will be knee pain, physical function and analgesia use. Analysis will be undertaken to identify characteristics associated with treatment responsiveness, such as high body mass index and structural disease severity. An economic analysis will be conducted alongside this trial.
Optimising Prevention And The Management Of Care For Australians With Or At Risk Of Serious And Continuing Chronic Illne
Funder
National Health and Medical Research Council
Funding Amount
$3,760,301.00
Summary
The project aims to study three prototype conditions - cardiovascular disease, diabetes and chronic obstructive pulmonary disease - in people aged 45 to 85 in the Sydney West Area Health Service and the Australian Capital Territory with a view to implementing and evaluating new models of care and developing policies that observe accurately the current state of the art technologies, discern the gaps in knowledge, locate the barriers to optimality and engage policy makers in practical proposals ab ....The project aims to study three prototype conditions - cardiovascular disease, diabetes and chronic obstructive pulmonary disease - in people aged 45 to 85 in the Sydney West Area Health Service and the Australian Capital Territory with a view to implementing and evaluating new models of care and developing policies that observe accurately the current state of the art technologies, discern the gaps in knowledge, locate the barriers to optimality and engage policy makers in practical proposals about how best to use the currently available resources to achieve better health outcomes.Read moreRead less