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Pharmacotherapy For Smoking Cessation Prior To And During Pregnancy
Funder
National Health and Medical Research Council
Funding Amount
$620,950.00
Summary
This study will examine the effectiveness and safety of medications for smoking cessation prior to and during pregnancy. It will achieve this by linking routinely collected midwives data from NSW and WA to prescriptions records and other health service use. It will explore potential inequalities in the use and effectiveness of these medications in disadvantaged populations, including Aboriginal women, and it will investigate whether their use has changed in response to policy changes.
Efficacy Of Education And Advice Delivered By Text Message To Aid Smoking Cessation
Funder
National Health and Medical Research Council
Funding Amount
$538,395.00
Summary
A high proportion of smokers indicate a desire to stop smoking and report having made attempts to quit. However, most attempts are not successful and new methods are needed to support motivated smokers and improve success rates. This project evaluates the use of text messages to deliver advice and support to smokers motivated to stop smoking. We aim to understand if and how this promosing new intervention helps smokers to quit.
The Natural History Of Unassisted Smoking Cessation In Australia
Funder
National Health and Medical Research Council
Funding Amount
$329,595.00
Summary
The majority of ex-smokers who successfully quit have done so without using pharmaceutical or counselling support. This study will produce pioneering insights into how and why so many smokers successfully quit without formal assistance. The findings will be conveyed to government, not-for-profit groups, and tobacco cessation professionals in order to help foster favourable social climates for smoking cessation and construct empowering messages about smoking cessation via self-change strategies.
An Open-label Randomised Pragmatic Policy Trial Of Nicotine Products For Short-term Cessation Assistance Or Long-term Substitution In Smokers.
Funder
National Health and Medical Research Council
Funding Amount
$1,053,910.00
Summary
Many smokers who try to quit fail in their attempt. Medicinal nicotine is currently only used as a short-term quit aid. This trial will test if offering smokers the option of using these products as long-term substitutes for cigarettes will help more smokers to successfully quit. We will also determine if offering smokers low toxicity smokeless tobacco and electronic nicotine devices in addition to medicinal nicotine products further increases the number of smokers who quit successfully.
Adding An Electronic-cigarette To Standard Behavioural Treatment For Low-socioeconomic Status Smokers: A Randomised Trial.
Funder
National Health and Medical Research Council
Funding Amount
$1,381,127.00
Summary
Behavioural and pharmacological approaches to smoking cessation are effective at helping people to quit but long-term quit rates remain low, especially among low-SES Australians. The electronic cigarette may complement current treatment approaches. We will conduct a large-scale trial to determine if “e-cigarettes” can improve on the efficacy of existing treatments. The findings would have immediate practical implications that could reduce the preventable deaths of many tobacco smokers.
Prediction And Prevention Of Spontaneous Preterm Birth: An Individual Participant Data Meta-Analysis Comprising Of Prognostic And Therapeutic Data
Funder
National Health and Medical Research Council
Funding Amount
$1,118,718.00
Summary
Spontaneous preterm birth is an important issue in obstetric care. Since potential treatments (pessary, progesterone) are available, accurate prediction is of imminent importance. We have established a collaborative network of >100 investigators (IPPIC-2) involved in primary studies with data on more than 1.2 milli women. We will estimate the value of individual clinical, biochemical and ultrasound markers for predicting preterm birth, and integrate that with therapeutic interventions.
Development Of Vinorelbine As A Tablet Based Therapy To Cure Ectopic Pregnancies
Funder
National Health and Medical Research Council
Funding Amount
$361,594.00
Summary
Ectopic pregnancies occur if the pregnancy implants in the Fallopian tube. They can be deadly and most are treated surgically. We will examine the exciting possibility that instead of surgery, ectopic pregnancies may be cured with a tablet taken just once. We will perform laboratory studies and a clinical trial, giving vinorelbine to women with ectopic pregnancies.
Quitlink: Accessible Smoking Cessation Support For People Living With Severe And Enduring Mental Illness
Funder
National Health and Medical Research Council
Funding Amount
$1,141,189.00
Summary
Smoking is the leading cause of preventable death in people with severe mental illness (SMI). Although smokers with SMI want to quit, tailored interventions are rarely delivered in practice. Quitlines are well placed but underutilised by this group. “Quitlink” will utilise peer workers within mental health services to engage smokers with SMI in a tailored Quitline intervention. We will also qualitatively examine facilitators and barriers to cessation in order to improve future interventions.
Randomised Controlled Trial Of A Financial Counselling Intervention And Smoking Cessation Assistance To Reduce Smoking In Socioeconomically Disadvantaged Groups
Funder
National Health and Medical Research Council
Funding Amount
$2,029,662.00
Summary
Socioeconomically disadvantaged groups are more likely to smoke than other sectors of the community. This difference has been attributed, in part, to increased rates of relapse. Relapse is strongly and consistently predicted by financial stress. This project attempts to reduce relapse by reducing financial stress among disadvantaged smokers through the provision of financial counselling as an adjunct to NRT.
Community Action For Smoking Cessation In Remote Aboriginal Communities
Funder
National Health and Medical Research Council
Funding Amount
$1,162,650.00
Summary
Smoking rates halved in Australia over the past 30 years to below 20% in 2004. However, Indigenous Australians continued to smoke at more than double this rate. In remote Aboriginal communities in the NT's 'Top End', over two-thirds of the population smoke. Smoking tobacco causes the greatest burden of disease for Australians generally. For Indigenous Australians, it is the single most important reversible risk factor for morbidity and premature mortality. With no sign of reduction in smoking le ....Smoking rates halved in Australia over the past 30 years to below 20% in 2004. However, Indigenous Australians continued to smoke at more than double this rate. In remote Aboriginal communities in the NT's 'Top End', over two-thirds of the population smoke. Smoking tobacco causes the greatest burden of disease for Australians generally. For Indigenous Australians, it is the single most important reversible risk factor for morbidity and premature mortality. With no sign of reduction in smoking levels, Indigenous Australians remain at greater risk of hospitalisations or death from many tobacco-related illnesses. Smoking in Australia was reduced through individually-oriented measures, public education and supply control. These strategies have either not been tried or have not been adequately studied in Aboriginal communities. Effective interventions could provide major health gains for Aboriginal Australians and reduce health costs. The intervention we propose will be based on an agreement whereby four remote communities in the 'Top End' will make a pact with the researchers to jointly try to reduce tobacco smoking using community-wide mobilisation, training and education. The intervention with have multiple components. We will not evaluate each component separately. The effect of the whole intervention on smoking will be assessed. Tobacco sales for the whole community in these small isolated localities, a sensitive and reliable measure, should decline if the intervention works. Tobacco smokers will be assessed before the intervention in each community and followed up twice to assess quit rates. Quit rates should go up. Five years are needed for the study because smoking behaviour change does not happen quickly or at peoples' first attempt. With staggered implementation of the intervention, i.e. not starting in all communities at once, reductions in smoking in more than one community will make us confident that the intervention worked.Read moreRead less