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Research Topic : Skin
Socio-Economic Objective : Mining and Extraction
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  • Funded Activity

    ARC Future Fellowships - Grant ID: FT0991283

    Funder
    Australian Research Council
    Funding Amount
    $686,400.00
    Summary
    Designed peptides as functional surfactants. Surfactants are essential in many applications for making oil-water mixtures, e.g. in dissolving drugs, extracting crude oil or spraying crops. However, chemical surfactants are toxic and can accumulate in the environment. This work will develop biodegradable surfactants that can be switched "on" and "off" as needed and do not cause toxicity to living organisms. One of many potential applications is in vaccines for use in remote Aboriginal communities .... Designed peptides as functional surfactants. Surfactants are essential in many applications for making oil-water mixtures, e.g. in dissolving drugs, extracting crude oil or spraying crops. However, chemical surfactants are toxic and can accumulate in the environment. This work will develop biodegradable surfactants that can be switched "on" and "off" as needed and do not cause toxicity to living organisms. One of many potential applications is in vaccines for use in remote Aboriginal communities. In these communities, skin infections from scabies and streptococcus are epidemic, and can lead to kidney failure and heart disease. A non-damaging skin cream based on the peptides could both treat short-term discomfort and deliver a vaccine to prevent long-term health consequences.
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