Maintaining bone strength in the elderly: the role of exercise and calcium fortified foods. There are currently no effective pharmacological agents for maintaining or increasing bone density during ageing available to older men with low bone strength. We aim to measure the effect on bone density and strength of older men who eat food products enhanced with calcium and vitamin D and undertake regular exercise. The results of this research will make an important contribution to knowledge about the ....Maintaining bone strength in the elderly: the role of exercise and calcium fortified foods. There are currently no effective pharmacological agents for maintaining or increasing bone density during ageing available to older men with low bone strength. We aim to measure the effect on bone density and strength of older men who eat food products enhanced with calcium and vitamin D and undertake regular exercise. The results of this research will make an important contribution to knowledge about the influence of diet and exercise on bone health. This research is also important for the food industry to ensure that the development of innovative food products is based on strong evidence.
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Engineering cartilage homeostasis in health and disease. Arthritis is a common, painful and often debilitating disease affecting 16% of the Australian population and costing this community $11 billion every year. It is not well understood why cartilage degenerates into joint disease, nor how it may be reversed - partly due to the large number of mechanisms involved. This project aims to overcome this complexity by developing a computational model of cartilage that can integrate the various mech ....Engineering cartilage homeostasis in health and disease. Arthritis is a common, painful and often debilitating disease affecting 16% of the Australian population and costing this community $11 billion every year. It is not well understood why cartilage degenerates into joint disease, nor how it may be reversed - partly due to the large number of mechanisms involved. This project aims to overcome this complexity by developing a computational model of cartilage that can integrate the various mechanisms of cartilage degradation. New experiments will be used to validate the model and test predictions. The model developed will provide fundamental insights into what is required for the maintenance of healthy cartilage, and what happens in injury-induced degradation of cartilage.Read moreRead less