Fibre-Polymer Composites With Graded Microstructure. This project concerns the development of a novel fibre-polymer functionally graded composite material that mimics the structure of the spinal disk. The spinal disk comprises a soft core (nucleus) and a tough fibrous periphery (annulus). The graded composite approach of this proposal represents a significant advance over spinal fusion, and over the current generation of spinal disk protheses (metal plates with springs/polymers as shock absorber ....Fibre-Polymer Composites With Graded Microstructure. This project concerns the development of a novel fibre-polymer functionally graded composite material that mimics the structure of the spinal disk. The spinal disk comprises a soft core (nucleus) and a tough fibrous periphery (annulus). The graded composite approach of this proposal represents a significant advance over spinal fusion, and over the current generation of spinal disk protheses (metal plates with springs/polymers as shock absorbers). Chronic back pain affects a significant proportion of the population and is primarily caused by failure of the spinal disk. Therefore a strong social and economic imperative exists to develop engineering solutions to this problem.Read moreRead less
Surface engineering of biomaterials for optimal bone bonding characteristics. The ideal bone-implant material is hydroxyapatite. Chemically similar to bone mineral, hydroxyapatite is capable of inducing bone ongrowth. An ideal surface coating for metal hip implants, plasma spraying has been the preferred commercial hydroxyapatite coating technique. Until recently, it was always presumed that the bioactivity of hydroxyapatite resulted from its surface chemistry. However, a recent study has shown ....Surface engineering of biomaterials for optimal bone bonding characteristics. The ideal bone-implant material is hydroxyapatite. Chemically similar to bone mineral, hydroxyapatite is capable of inducing bone ongrowth. An ideal surface coating for metal hip implants, plasma spraying has been the preferred commercial hydroxyapatite coating technique. Until recently, it was always presumed that the bioactivity of hydroxyapatite resulted from its surface chemistry. However, a recent study has shown that the bioactivity of HAp coatings strongly correlates with surface roughness on the scale of bone cells. This project will explore cell-attachment behaviour for hydroxyapatite coatings prepared by plasma spraying compared with engineered surface morphology/chemistry by microlithography and vapour coating.Read moreRead less
Functionally graded fibre-polymer composites: a novel material for spinal disk prostheses. Chronic back pain affects a significant proportion of the population and is primarily caused by failure of the spinal disk. A strong social/economic imperative exists to develop engineering solutions to this problem. This project concerns the development of a novel fibre-polymer functionally graded composite material that mimics the structure of the spinal disk. The spinal disk comprises a soft core (nucle ....Functionally graded fibre-polymer composites: a novel material for spinal disk prostheses. Chronic back pain affects a significant proportion of the population and is primarily caused by failure of the spinal disk. A strong social/economic imperative exists to develop engineering solutions to this problem. This project concerns the development of a novel fibre-polymer functionally graded composite material that mimics the structure of the spinal disk. The spinal disk comprises a soft core (nucleus) and a tough fibrous periphery (annulus). The graded composite approach of this proposal represents a significant advance over spinal fusion, and over the alternative spinal disk protheses in clinical use or in the patent literature.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0561186
Funder
Australian Research Council
Funding Amount
$447,967.00
Summary
Surface Mechanical Property Analysis Facility. The aim of this proposal is to develop a facility for the mechanical properties analysis of material surfaces. The facility will enable an understanding of the performance of materials in a wide range of contact and abrasion situations and in very small volumes such as thin films and components of multiphase composites. The unique features of the proposed facility are that it is capable of analysis down to exceptionally low sub-micron length scale, ....Surface Mechanical Property Analysis Facility. The aim of this proposal is to develop a facility for the mechanical properties analysis of material surfaces. The facility will enable an understanding of the performance of materials in a wide range of contact and abrasion situations and in very small volumes such as thin films and components of multiphase composites. The unique features of the proposed facility are that it is capable of analysis down to exceptionally low sub-micron length scale, under multiple forms of loading and over a range of temperatures. It is applicable to the design of abrasion resistant materials, characterisation of very thin surface films for applications such as microelectronics and biomedical implants and design of advanced composites.Read moreRead less
Guided droplet deposition: Microfabrication of advanced materials. The progress of micro and nanofabrication is opening an array of new opportunities with a new degree of freedom for manufacturing. This process will complement the existing micromanufacturing facilities in Melbourne. While metal printing and deposition of polymers is presently available, the guided droplet deposition will extend current capabilities to include ceramics and high melting temperature metals. Direct application to me ....Guided droplet deposition: Microfabrication of advanced materials. The progress of micro and nanofabrication is opening an array of new opportunities with a new degree of freedom for manufacturing. This process will complement the existing micromanufacturing facilities in Melbourne. While metal printing and deposition of polymers is presently available, the guided droplet deposition will extend current capabilities to include ceramics and high melting temperature metals. Direct application to medical devices will provide a more effective surface for improved performance and allow the incorporation of smart and sensor materials for multifunctional devices. Read moreRead less
Determination of the Properties of Hyper-Elastic Materials by Deep Indentation. We seek to develop the scientific basis for the interpretation of the results of "deep" indentation testing of non-linear elastic (hyper-elastic) materials. Simple tests (such as indentation) produce complex strain fields. Interpretation of the resulting data in terms of stiffness, for example, requires a complex model of the deformation process that can be utilised to link the observed behaviour to the basic prope ....Determination of the Properties of Hyper-Elastic Materials by Deep Indentation. We seek to develop the scientific basis for the interpretation of the results of "deep" indentation testing of non-linear elastic (hyper-elastic) materials. Simple tests (such as indentation) produce complex strain fields. Interpretation of the resulting data in terms of stiffness, for example, requires a complex model of the deformation process that can be utilised to link the observed behaviour to the basic properties of interest. This project is dedicated to an understanding of the complex deformation associated with large strain indentation of hyper-elastic materials and structures, development of finite element based models for this deformation and creation of techniques for interpretation of the results of such indentation tests.Read moreRead less
Miniature lithium ion battery for implantable medical device applications. This project addresses National Research Priorities in the areas of breakthrough science, frontier technologies and promoting and maintaining good health. Substantial national benefit could be derived from this project: (i) Australia will innovate in an important and intensely active area in which the results will have long-lasting significance in implantable rechargeable battery development; (ii)The development of new sc ....Miniature lithium ion battery for implantable medical device applications. This project addresses National Research Priorities in the areas of breakthrough science, frontier technologies and promoting and maintaining good health. Substantial national benefit could be derived from this project: (i) Australia will innovate in an important and intensely active area in which the results will have long-lasting significance in implantable rechargeable battery development; (ii)The development of new scientific knowledge related to this project will place Australia at the forefront of an emerging domain of research body batteries; (iii) In the long term, the successful outcome of this research will lead to more reliable batteries for implantable devices, thereby promoting health care.Read moreRead less
Failure modes in ceramic-based layer structures: Relevance to failure of dental crowns. With the aging of our population, issues concerning the lifetime of biological system are paramount to the quality of life and economic well being of our society. This project is closely linked to the development of prosthetic materials and structures that will improve performance and life of biomechanical devices, by providing better understanding to the mechanics of failure and failure origins of ceramic-ba ....Failure modes in ceramic-based layer structures: Relevance to failure of dental crowns. With the aging of our population, issues concerning the lifetime of biological system are paramount to the quality of life and economic well being of our society. This project is closely linked to the development of prosthetic materials and structures that will improve performance and life of biomechanical devices, by providing better understanding to the mechanics of failure and failure origins of ceramic-based dental crowns and restorations, and to develop materials that will withstand exacting conditions - in body fluids - over extended lifetimes. Crown replacement is by far the most widespread of all prosthetic procedures. This project promises to help bridge the gap between physical and medical science in Australia. Read moreRead less
Bioactive Polymers for Wound Healing Applications. VitroGroR is a growth factor complex which enhances cell growth and migration, and hence has great potential for treating wounds. Tissue Therapies, which holds the rights to commercialization of VitroGroR, is seeking to develop methods of delivering VitroGroR in its active form to the wound environment. Two solutions to this problem will be developed in this project; a bioactive bandage containing a novel combination of microspheres and a hydrog ....Bioactive Polymers for Wound Healing Applications. VitroGroR is a growth factor complex which enhances cell growth and migration, and hence has great potential for treating wounds. Tissue Therapies, which holds the rights to commercialization of VitroGroR, is seeking to develop methods of delivering VitroGroR in its active form to the wound environment. Two solutions to this problem will be developed in this project; a bioactive bandage containing a novel combination of microspheres and a hydrogel matrix, and secondly an in-situ polymerisable matrix for treatment of deep wounds. The growth factor complex will be protected from aggressive proteases through encapsulation within microspheres, and the use of MMP-inhibiting comonomers.Read moreRead less
Photoactive Semiconducting Biopolymers. The basic aims of this project are to elucidate, manipulate, and utilise the unique chemical and physical properties of a class of biopolymers called the melanins. These materials are the only known solid state semiconducting biopolymers, and are non-toxic, biocompatible, and biodegradable. Their use as active components in biomimetic soft electonic, optoelectronic or photovoltaic devices, has not hitherto been demonstrated. It is anticipated that the k ....Photoactive Semiconducting Biopolymers. The basic aims of this project are to elucidate, manipulate, and utilise the unique chemical and physical properties of a class of biopolymers called the melanins. These materials are the only known solid state semiconducting biopolymers, and are non-toxic, biocompatible, and biodegradable. Their use as active components in biomimetic soft electonic, optoelectronic or photovoltaic devices, has not hitherto been demonstrated. It is anticipated that the key outcomes from the project will be a demonstration of biopolymer-based photoelectrochemical and solid-state p-i-n solar cells, and an improved understanding of the physics and chemistry of these important biological macromolecules.Read moreRead less