Osteoarthritis Compass: Predicting Personalized Disease Onset And Progression With Future Capacity For Clinical Use.
Funder
National Health and Medical Research Council
Funding Amount
$860,231.00
Summary
Knee osteoarthritis (OA) is common, painful, and costly. General guidelines for knee OA management exist but cannot be personalized to the patient. New computer modelling methods enable prediction of knee OA onset and progression on a patient by patient basis but need further testing. Our aims are to 1) apply these new computer modelling methods to legacy datasets acquired from patient groups at risk of, and with, knee OA, and 2) make these models simple and fast enough to be clinically useful.
Dynamic CFD Simulations and Scale-Up of Three-Phase Slurry Reactors for Gas-to-Liquid (GTL) Technology. The gas-liquid-solid flow patterns in three-phase slurry bubble column reactors will be studied using experiments and CFD. The effect of various reactor parameters will be studied to develop the scale-up heuristic for the slurry bubble column reactor. The Findings of this study will be used to optimise the reactor system for the offshore natural gas locations of Australia. A successful impleme ....Dynamic CFD Simulations and Scale-Up of Three-Phase Slurry Reactors for Gas-to-Liquid (GTL) Technology. The gas-liquid-solid flow patterns in three-phase slurry bubble column reactors will be studied using experiments and CFD. The effect of various reactor parameters will be studied to develop the scale-up heuristic for the slurry bubble column reactor. The Findings of this study will be used to optimise the reactor system for the offshore natural gas locations of Australia. A successful implementation of this project will bring a huge economic benefit to Australia by utilising the vast amount of remotely located and otherwise unusable stranded natural gas reserves. The project falls within one of National Research Priorities: An Environmentally Sustainable Australia.Read moreRead less
Economic Operability Assessment of Leaching Process at Kwinana Nickel Refinery. Process operability is concerned with systematic analysis and improvement of process performance in the face of variable operating conditions. This project will develop a rigorous methodology for analysis of process operability with respect to short-term and transient disturbances. The proposed technique will be applied to the Kwinana Nickel Refinery Leach section, in order to reduce the plant variability and increas ....Economic Operability Assessment of Leaching Process at Kwinana Nickel Refinery. Process operability is concerned with systematic analysis and improvement of process performance in the face of variable operating conditions. This project will develop a rigorous methodology for analysis of process operability with respect to short-term and transient disturbances. The proposed technique will be applied to the Kwinana Nickel Refinery Leach section, in order to reduce the plant variability and increase nickel throughput and plant availability. This can be considered as significant move by a process industry to embrace advanced theoretical developments and will act as a benchmark to promote future links between Australian industry and academia.Read moreRead less
Thermal management of methane fuelled planar solid oxide fuel cells. Solid oxide fuel cells (SOFCs) are novel devices for generating energy with extremely low emissions. This project will conduct novel experiments and numerical simulations to improve the efficiency of SOFCs. This will then allow wider adoption of this technology, thus reducing CO2 and other environmental emissions from our power generation systems.
International partnership in robotic astronomy and gravitational wave data analysis using a supercomputer. The project is aimed at providing student participation in frontier research using robotic astronomy and novel data analysis methods. It will focus on the study of the most violent explosions in the Universe - cosmological gamma ray bursts. These cataclysmic events possibly herald the formation of the most exotic objects in the Universe - black holes. It provides an exciting opportunity for ....International partnership in robotic astronomy and gravitational wave data analysis using a supercomputer. The project is aimed at providing student participation in frontier research using robotic astronomy and novel data analysis methods. It will focus on the study of the most violent explosions in the Universe - cosmological gamma ray bursts. These cataclysmic events possibly herald the formation of the most exotic objects in the Universe - black holes. It provides an exciting opportunity for students to be trained in robotic astronomy, supercomputing, image analysis and signal processing.Read moreRead less
WAVELET-BASED MODELLING AND MODEL PREDICTIVE CONTROL OF COMPLEX MULTIDIMENSIONAL CRYSTALLISATION PROCESSES. The results of this project will directly contribute to a better understanding of crystallisation which is an important unit operation to achieve high purity separations. Many Australian industries for example, mineral processing, sugar processing, pharmaceuticals, etc will benefit from the results in order to enhance optimal operation and control to ensure globally competitive production ....WAVELET-BASED MODELLING AND MODEL PREDICTIVE CONTROL OF COMPLEX MULTIDIMENSIONAL CRYSTALLISATION PROCESSES. The results of this project will directly contribute to a better understanding of crystallisation which is an important unit operation to achieve high purity separations. Many Australian industries for example, mineral processing, sugar processing, pharmaceuticals, etc will benefit from the results in order to enhance optimal operation and control to ensure globally competitive production which is on time, minimize wastes and raw materials and inventories. The leading edge results will increase the contributions of these industries to the Australian economy and our global competitiveness necessary to maintain our culture and the beauty of our environment. Read moreRead less
Multiscale Integrated Modelling and Control of an Ethanol-Fuelled Tubular Solid Oxide Fuel Cell. The results from this project will allow use of alternative sources for energy through a better understanding of the functioning, design, operability and control of SOFCs. Fuel Cells (FCs) with biomass ethanol feed will not only act as reliable power source but also reduce greenhouse gas emissions. A successful R&D effort to develop FCs will improve the national energy security by reducing the growin ....Multiscale Integrated Modelling and Control of an Ethanol-Fuelled Tubular Solid Oxide Fuel Cell. The results from this project will allow use of alternative sources for energy through a better understanding of the functioning, design, operability and control of SOFCs. Fuel Cells (FCs) with biomass ethanol feed will not only act as reliable power source but also reduce greenhouse gas emissions. A successful R&D effort to develop FCs will improve the national energy security by reducing the growing dependency on foreign energy sources, improve the environment by reducing carbon and other harmful emissions, and improve the economic growth by expanding the portfolio of highly efficient energy and useful spill over technologies. Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH130200012
Funder
Australian Research Council
Funding Amount
$2,748,358.00
Summary
ARC Research Hub for Basin GEodyNamics and Evolution of SedImentary Systems (GENESIS). ARC Research Hub for Basin GEodyNamics and Evolution of SedImentary Systems (GENESIS). This Research Hub aims to undertake simultaneous modelling of deep Earth and surface processes, spanning basin scales to individual sediment grains. The Hub will develop and apply cutting-edge basin simulation approaches to transform the seeding and testing of basin exploration models, extending their viability to complex, ....ARC Research Hub for Basin GEodyNamics and Evolution of SedImentary Systems (GENESIS). ARC Research Hub for Basin GEodyNamics and Evolution of SedImentary Systems (GENESIS). This Research Hub aims to undertake simultaneous modelling of deep Earth and surface processes, spanning basin scales to individual sediment grains. The Hub will develop and apply cutting-edge basin simulation approaches to transform the seeding and testing of basin exploration models, extending their viability to complex, inaccessible remote and deep exploration targets. The Hub will fuse multidimensional data into five dimensional basin models (space and time, with uncertainty estimates) by coupling the evolution of mantle flow, crustal deformation, erosion and sedimentary processes, achieving a quantum leap in basin modelling and petroleum systems analysis.Read moreRead less
Simulation Technology for Modelling Extreme Bushfire Behaviour. Extreme fires cause immeasurable damage to communities through destruction of homes and damage to infrastructure. Large, highly intense fires reduce biodiversity, take decades for recovery, increase greenhouse gas emissions and reduce carbon storage capacity. Climate change is likely to increase the frequency of extreme fire weather increasing the need for reliable fire spread prediction under extreme conditions and to reduce impa ....Simulation Technology for Modelling Extreme Bushfire Behaviour. Extreme fires cause immeasurable damage to communities through destruction of homes and damage to infrastructure. Large, highly intense fires reduce biodiversity, take decades for recovery, increase greenhouse gas emissions and reduce carbon storage capacity. Climate change is likely to increase the frequency of extreme fire weather increasing the need for reliable fire spread prediction under extreme conditions and to reduce impact by preparedness and suppression. Incorporating an evidence-based fire spread model into a fire location forecasting system will give fire agencies early warning of potentially disastrous fires, enable early response to prevent fires and mitigate the consequence to life, property and the environment. Read moreRead less
Increasing the operational lifetime and optimising the design of crankcase oil-mist filters. Australia is one of the largest (per capita) users worldwide of heavy diesel engines, within sectors such as transport, mining, construction, shipping and power generation (usage of many of the above is concentrated in regional communities e.g. mining). This work will minimise emissions from such industries, as well as reduce lubricant oil usage - thereby maximising waste oil recovery and reuse (approx 5 ....Increasing the operational lifetime and optimising the design of crankcase oil-mist filters. Australia is one of the largest (per capita) users worldwide of heavy diesel engines, within sectors such as transport, mining, construction, shipping and power generation (usage of many of the above is concentrated in regional communities e.g. mining). This work will minimise emissions from such industries, as well as reduce lubricant oil usage - thereby maximising waste oil recovery and reuse (approx 5500 tonnes p.a.). Oil mists can be regarded as volatile organic compounds (VOCs) for the purposes of CO2 equivalent emissions, so therefore, the efficient capture of oil mists will reduce carbon emissions from the above industries in Australia.Read moreRead less