Robust, valid and interpretable deep learning for quantitative imaging. One of the biggest challenges in employing artificial intelligence is the “black-box” nature of the models used. This project aims to improve the effectiveness and trustworthiness of deep learning within quantitative magnetic resonance imaging. Deep learning has great promise in speeding-up complex image processing tasks, but currently suffers from variable data inputs, predictions are not guaranteed to be plausible and it i ....Robust, valid and interpretable deep learning for quantitative imaging. One of the biggest challenges in employing artificial intelligence is the “black-box” nature of the models used. This project aims to improve the effectiveness and trustworthiness of deep learning within quantitative magnetic resonance imaging. Deep learning has great promise in speeding-up complex image processing tasks, but currently suffers from variable data inputs, predictions are not guaranteed to be plausible and it is not clear to the end user how reliable the results are. The outcomes intend to deliver advanced knowledge and capability in artificial intelligence and machine learning that Australia urgently needs to capitalise on bringing deep learning into practical applications delivering economic, commercial and social impact.Read moreRead less
Nanopore sensors for multiplexed, ultra-fast gene detection. The aim of this research is to develop the application of protein nanopores for multiplex identification of DNA samples for ultrafast gene detection. This is a type of barcoding of organism DNA that allows for rapid gene identification. This technology aims to address a significant need for rapid, on-the-spot identification of organisms. Applications include rapid identification of pathogenic bacteria in infections and identification o ....Nanopore sensors for multiplexed, ultra-fast gene detection. The aim of this research is to develop the application of protein nanopores for multiplex identification of DNA samples for ultrafast gene detection. This is a type of barcoding of organism DNA that allows for rapid gene identification. This technology aims to address a significant need for rapid, on-the-spot identification of organisms. Applications include rapid identification of pathogenic bacteria in infections and identification of organisms in environmental sampling. Current methods are relative slow, require DNA amplification and specialised laboratories.
This proposal aims to fine tune the properties of the large nanopore, polyC9, with respect to size and charge, as well as to identify and characterise novel large nanopores. Read moreRead less
Enlightening single rare-earth atoms in scanning-tunnelling microscopy. This project aims to create a tool to systematically engineer optical properties of emitters in solids by understanding and manipulating materials atom by atom. The tool – an optically enhanced scanning tunnelling microscope – is expected to drive future developments in optical technologies. The project expects to deliver an atomic-scale understanding of rare-earth sites optimised for sensing and coherence. The expected outc ....Enlightening single rare-earth atoms in scanning-tunnelling microscopy. This project aims to create a tool to systematically engineer optical properties of emitters in solids by understanding and manipulating materials atom by atom. The tool – an optically enhanced scanning tunnelling microscope – is expected to drive future developments in optical technologies. The project expects to deliver an atomic-scale understanding of rare-earth sites optimised for sensing and coherence. The expected outcomes include highly developed theoretical insights into solid-state emitters and how to control their interactions with light and other fields. The expected benefit based on the ability to engineer optimised emitters for optical sensors and quantum technologies will transform material science from exploration to design.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE240100010
Funder
Australian Research Council
Funding Amount
$928,291.00
Summary
Single-molecule Manipulation and Interaction Facility (SMIF). This LIEF project aims to establish Australia's first Single-molecule Manipulation and Interaction Facility (SMIF), providing multidisciplinary researchers with a platform to explore cellular processes and reveal molecular mechanisms at the nanoscale. The SMIF facility incorporates cutting-edge technologies for bio-manipulation, real-time visualisation, and characterisation of single-molecule interactions, overcoming the technical com ....Single-molecule Manipulation and Interaction Facility (SMIF). This LIEF project aims to establish Australia's first Single-molecule Manipulation and Interaction Facility (SMIF), providing multidisciplinary researchers with a platform to explore cellular processes and reveal molecular mechanisms at the nanoscale. The SMIF facility incorporates cutting-edge technologies for bio-manipulation, real-time visualisation, and characterisation of single-molecule interactions, overcoming the technical complexity of traditional tools requiring highly specialised personnel. By offering accessible, easy-to-use advanced systems, this project will significantly boost scientific discovery across physics, chemistry, and biology, fostering collaboration and innovation to better understand life at the molecular level.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE210101904
Funder
Australian Research Council
Funding Amount
$385,322.00
Summary
Next-Generation LIDAR with Novel Microresonator Frequency Combs. This project aims to develop the science that would enable a new low-cost laser radar (LIDAR) for imaging the world around us. LIDAR has applications in facial recognition, forestry and autonomous vehicles – our new device will uniquely offer the ability to work underwater thereby opening up new possibilities for maritime environmental and vehicle monitoring. Our approach exploits a new form of optical pulse propagation in precise ....Next-Generation LIDAR with Novel Microresonator Frequency Combs. This project aims to develop the science that would enable a new low-cost laser radar (LIDAR) for imaging the world around us. LIDAR has applications in facial recognition, forestry and autonomous vehicles – our new device will uniquely offer the ability to work underwater thereby opening up new possibilities for maritime environmental and vehicle monitoring. Our approach exploits a new form of optical pulse propagation in precisely shaped crystals to generate bespoke laser pulses that enable high-speed and precise ranging to targets of interest. The science behind these new types of optical pulses offers the ability for Australia to lead a new scientifically and industrially important field.Read moreRead less
Repetitive control systems in networked environments. Repetitive control is used in many industry applications to track periodic references and reject periodic disturbances. The development of digital technology brings in more networked control systems, greatly improving distributed manufacturing, which creates new design challenges due to network-induced constraints such as delay, data packet dropouts and cyber-attacks. This project aims to provide new understanding of dynamic behaviours of rep ....Repetitive control systems in networked environments. Repetitive control is used in many industry applications to track periodic references and reject periodic disturbances. The development of digital technology brings in more networked control systems, greatly improving distributed manufacturing, which creates new design challenges due to network-induced constraints such as delay, data packet dropouts and cyber-attacks. This project aims to provide new understanding of dynamic behaviours of repetitive control systems in networked environments, and develop a new theory for the analysis and design of networked repetitive control, subject to network induced constraints. The new control systems should reduce the cost of automation systems and will significantly enhance their performance, allowing Australian industry to remain economically competitive.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC170100023
Funder
Australian Research Council
Funding Amount
$4,619,950.00
Summary
ARC Training Centre for Cubesats, Uncrewed Aerial Vehicles, and Their Applications. The ARC Training Centre for CubeSats, Unmanned Aerial Vehicles and their Applications aims to train the next generation of workers in cutting edge advanced manufacturing, entrepreneurship, and commercial space and unmanned aerial vehicle applications. The Australian economy, security, and society increasingly rely on access to space for vital data and services, and a skilled workforce is required to grow the sec ....ARC Training Centre for Cubesats, Uncrewed Aerial Vehicles, and Their Applications. The ARC Training Centre for CubeSats, Unmanned Aerial Vehicles and their Applications aims to train the next generation of workers in cutting edge advanced manufacturing, entrepreneurship, and commercial space and unmanned aerial vehicle applications. The Australian economy, security, and society increasingly rely on access to space for vital data and services, and a skilled workforce is required to grow the sector and capitalise on global opportunities. Of great commercial value, with very low costs, CubeSats are a new class of small satellites, which with UAVs are disrupting the international satellite market. The expected outcome of this Training Centre is to develop new instruments, technology and products to solve crucial problems, and develop a world-class Australian industry in CubeSats, unmanned aerial vehicles, and related products.Read moreRead less
High-resolution optical studies of solids nucleation in cryogenic processes. During liquefied natural gas (LNG) production, low concentration impurities can freeze and block the cryogenic heat exchangers at the heart of the liquefaction process. Substantial knowledge gaps exist regarding the kinetics of these solids (i.e. the rate at which they form), especially at the part per million concentrations relevant to LNG. This project, in partnership with ExxonMobil Upstream Research Company, will us ....High-resolution optical studies of solids nucleation in cryogenic processes. During liquefied natural gas (LNG) production, low concentration impurities can freeze and block the cryogenic heat exchangers at the heart of the liquefaction process. Substantial knowledge gaps exist regarding the kinetics of these solids (i.e. the rate at which they form), especially at the part per million concentrations relevant to LNG. This project, in partnership with ExxonMobil Upstream Research Company, will use a proven high resolution optical technique to deliver new insight into solid nucleation and growth kinetics in the high-pressure cryogenic fluids that govern industrial blockage risk. The results will enable energy optimisation to increase liquefaction efficiency as well as tests of innovative blockage-remediation methods.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100002
Funder
Australian Research Council
Funding Amount
$3,000,000.00
Summary
Australian Partnership in Advanced LIGO+: continuation. The aim of this project is, in collaboration with the USA and UK, to complete the installation and commissioning of the Advanced LIGO+ facilities in the USA in order to bring them to design sensitivity. These facilities expect to increase the event rate of gravitational wave signals by a factor of 125. This should lead to daily detections and the observation of new sources of gravitational waves. Given that only 5% of the universe is detect ....Australian Partnership in Advanced LIGO+: continuation. The aim of this project is, in collaboration with the USA and UK, to complete the installation and commissioning of the Advanced LIGO+ facilities in the USA in order to bring them to design sensitivity. These facilities expect to increase the event rate of gravitational wave signals by a factor of 125. This should lead to daily detections and the observation of new sources of gravitational waves. Given that only 5% of the universe is detectable by telescopes, the impact of gravitational wave detections on our understanding of the universe is inestimable. Australian partnership intends to enable our physicists and astronomers to be at the vanguard of this brand new field and inspire a new generation to study the physical sciences.Read moreRead less
Noise-free Cryogenic Wavefront Sensing. This project aims to optimise the prototype adaptive optics technology for the Giant Magellan Telescope (GMT) by leveraging past investment in adaptive optics instrumentation and shortwave infrared detector systems. This project expects to generate significant improvements in GMT performance, with ten times greater image resolution than the Hubble Space Telescope and current estimates of >90% sky coverage, compared with ~50% coverage for current technology ....Noise-free Cryogenic Wavefront Sensing. This project aims to optimise the prototype adaptive optics technology for the Giant Magellan Telescope (GMT) by leveraging past investment in adaptive optics instrumentation and shortwave infrared detector systems. This project expects to generate significant improvements in GMT performance, with ten times greater image resolution than the Hubble Space Telescope and current estimates of >90% sky coverage, compared with ~50% coverage for current technology. Expected outcomes of this project include the development of a highly trained workforce and continued international collaboration in the field of high-technology sensor systems. This contribution to the GMT will provide significant benefits—it will change the way we view the Universe.Read moreRead less