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Cardiovascular Effects Of Enhanced Leptin Signalling
Funder
National Health and Medical Research Council
Funding Amount
$1,200,972.00
Summary
Leptin treatment causes weight loss, but leptin also increases blood pressure. We wish to determine if increasing leptin signalling, by modifying signal transduction pathways within leptin sensitive cells in the brain, can reduce weight without increasing blood pressure.
I am a protein chemist-vascular biologist analysing structure, function and clinical role of platelet adhesion receptors regulating patho-physiological thrombus formation associated with thrombotic diseases such as heart attack and stroke.