Functional Strontium Phosphate Coated Magnesium Alloys For ?Orthopaedic Use. This project aims to develop a functional strontium-release surface on magnesium-based orthopaedic implants to suppress the rapid degradation rate of magnesium, facilitate new bone formation and ultimately shorten the healing process. The development of practical, bone-favourable and degradation-inhibiting surfaces for magnesium implants are in demand and can bring significant patient benefits. The project seeks to esta ....Functional Strontium Phosphate Coated Magnesium Alloys For ?Orthopaedic Use. This project aims to develop a functional strontium-release surface on magnesium-based orthopaedic implants to suppress the rapid degradation rate of magnesium, facilitate new bone formation and ultimately shorten the healing process. The development of practical, bone-favourable and degradation-inhibiting surfaces for magnesium implants are in demand and can bring significant patient benefits. The project seeks to establish an understanding of the formation mechanisms of strontium-releasing coatings and determine the critical release rate of strontium to activate bone cell responses.Read moreRead less
Elastic softening of Ti alloys by plastic deformation for safer and more durable bone implants. This project will explore a critical factor that will form the basis of improving the biomechanical compatibility of titanium alloys for human bone implants. The outcomes will be a major step in optimising the design and development of human bone implants that will last a lifetime, avoiding the agony and risk associated with implant failure.
Discovery Early Career Researcher Award - Grant ID: DE190101495
Funder
Australian Research Council
Funding Amount
$408,000.00
Summary
Biodegradable porous shape memory alloys by additive manufacturing. This project aims to create a class of biodegradable Fe-Mn-Si based shape memory alloys and use additive manufacturing to fabricate porous structures with desired properties from these shape memory alloys. Biodegradable shape memory alloys offer great promise for biomedical applications due to their unique biodegradability, shape memory effects and superelasticity. However, a huge knowledge gap exists in developing and fabricati ....Biodegradable porous shape memory alloys by additive manufacturing. This project aims to create a class of biodegradable Fe-Mn-Si based shape memory alloys and use additive manufacturing to fabricate porous structures with desired properties from these shape memory alloys. Biodegradable shape memory alloys offer great promise for biomedical applications due to their unique biodegradability, shape memory effects and superelasticity. However, a huge knowledge gap exists in developing and fabricating biodegradable shape memory alloys with desired properties for biomedical applications. The project expects to fill the critical knowledge gap and open up new opportunities for biomedical applications of biodegradable shape memory alloys. This project will provide significant benefits through the creation of novel materials for application in the healthcare industry such as biomedical devices.Read moreRead less
Stronger zinc alloys for more flexible biodegradable stents. This project aims to develop stronger zinc alloys for a new class of biodegradable metallic stents. A key challenge for biodegradable stent technology is to make stents as thin as possible while also being strong. This project will develop ultra-high strength zinc alloys that can be used to fabricate thinner biodegradable stents for easier surgical operation. The project outcomes should be a major step in the design and development of ....Stronger zinc alloys for more flexible biodegradable stents. This project aims to develop stronger zinc alloys for a new class of biodegradable metallic stents. A key challenge for biodegradable stent technology is to make stents as thin as possible while also being strong. This project will develop ultra-high strength zinc alloys that can be used to fabricate thinner biodegradable stents for easier surgical operation. The project outcomes should be a major step in the design and development of a new generation of biodegradable stents that will avoid the risks associated with existing products and potentially create a better life for millions of patients worldwide.Read moreRead less
Biodegradable magnesium alloy scaffolds for bone tissue engineering. This project aims to develop a class of porous, biocompatible, biofunctional and biodegradable magnesium alloy scaffolds with designed pore architecture and mechanical properties mimicking those of natural bone for tissue engineering applications. These magnesium alloy scaffolds will be biocompatible, able to bear loads, and will be gradually replaced by natural bone. The outcomes are expected to benefit the ageing population a ....Biodegradable magnesium alloy scaffolds for bone tissue engineering. This project aims to develop a class of porous, biocompatible, biofunctional and biodegradable magnesium alloy scaffolds with designed pore architecture and mechanical properties mimicking those of natural bone for tissue engineering applications. These magnesium alloy scaffolds will be biocompatible, able to bear loads, and will be gradually replaced by natural bone. The outcomes are expected to benefit the ageing population and people with bone abnormalities.Read moreRead less
X-Ray Activation of Photocatalytic Titania-Coated Biomedical Implants in Situ. The main causes of biomedical implant failure are loosening and infection, which may require revision surgery. The project has the potential to solve these widespread and expensive problems by formation of a coating of strongly (chemically) bonded and photocatalytically active titania on the titanium implant surface and short-term low-dose X-irradiation. This work has the potential to provide the biomedical industry w ....X-Ray Activation of Photocatalytic Titania-Coated Biomedical Implants in Situ. The main causes of biomedical implant failure are loosening and infection, which may require revision surgery. The project has the potential to solve these widespread and expensive problems by formation of a coating of strongly (chemically) bonded and photocatalytically active titania on the titanium implant surface and short-term low-dose X-irradiation. This work has the potential to provide the biomedical industry with a revolutionary development in both implant coating design and quality with self-disinfection capacity after implantation.Read moreRead less
Highly ordered and tunable extracellular DNA micro- and nanopatterns for investigating the attachment mechanisms of pseudomonas aeruginosa to surfaces. Preventing infectious bacteria from colonising artificial surfaces is a major scientific challenge. New engineered surfaces will be designed to better understand how the important pathogen Pseudomonas aeruginosa sticks to surfaces, facilitating new ways of reducing infections acquired from the surface of, for example, medical devices.
Processing - Structure Relationships in Thermal Spray Coatings. Researchers in New Zealand have developed novel thermal spray processing treatments which can be used to enahnce the wear, oxidation and corrosion resisitance of materials. However, characterization of the coatings using electron microscopy is essential to understand the relationship between processing conditions and properties. The aim of this project is to draw together specialist expertise and equipment that allows integration ....Processing - Structure Relationships in Thermal Spray Coatings. Researchers in New Zealand have developed novel thermal spray processing treatments which can be used to enahnce the wear, oxidation and corrosion resisitance of materials. However, characterization of the coatings using electron microscopy is essential to understand the relationship between processing conditions and properties. The aim of this project is to draw together specialist expertise and equipment that allows integration of microscopy into the development of these films. Australian researchers will gain access to specialized preparation and testing facilities in New Zealand, whilst researchers from New Zealand will perform structural analysis of these films in Australia.Read moreRead less
Interfacial Structures in Thermal Spray Coatings. The use of coatings on the surfaces of components provides high levels of resistance to mechanical damage, corrosion, oxidation or thermal degradation. As a result, coated components exhibit increased lifetimes and reliability. However, the durability of such components is still crucially limited by the quality of the coating. An improved understanding of the bonding mechanisms that occur during the deposition of such coatings, prepared through t ....Interfacial Structures in Thermal Spray Coatings. The use of coatings on the surfaces of components provides high levels of resistance to mechanical damage, corrosion, oxidation or thermal degradation. As a result, coated components exhibit increased lifetimes and reliability. However, the durability of such components is still crucially limited by the quality of the coating. An improved understanding of the bonding mechanisms that occur during the deposition of such coatings, prepared through thermal spray methods, will provide improvements in coating structure and thus, component performance and lifetime. This will benefit a wide range of manufacturing industries that use such coatings. Read moreRead less
Design of Tough, Durable and Corrosion-resistant Coatings. Coatings are frequently applied to components operating in harsh environments to enhance durability. Often such coatings exhibit low toughness and poor corrosion resistance that leads to premature failure. The aim of this project is to design, characterise and test innovative coatings that exhibit unique architectures based on natural materials such as teeth and nacre. It is envisaged that these coatings will be hard, tough and durable i ....Design of Tough, Durable and Corrosion-resistant Coatings. Coatings are frequently applied to components operating in harsh environments to enhance durability. Often such coatings exhibit low toughness and poor corrosion resistance that leads to premature failure. The aim of this project is to design, characterise and test innovative coatings that exhibit unique architectures based on natural materials such as teeth and nacre. It is envisaged that these coatings will be hard, tough and durable in hostile, corrosive environments, and will thus, transform industries such as manufacturing, mining and offshore oil exploration as well as enhance the lifetime of prosthetic devices.Read moreRead less