The Second Australian Study Of Health And Relationships
Funder
National Health and Medical Research Council
Funding Amount
$1,637,477.00
Summary
The present proposal is for the Second Australian Study of Health and Relationships, a survey of 20,000 Australians aged 16–69, in 2011–12 in order to understand and document the changes in Australian sexual behaviour over the past decade. It is essential that policy and practice in the arena of sexual and reproductive health be evidence-based and that the evidence base be as current as is practicable.
Polycystic ovary syndrome (PCOS) affects 5-10% of women worldwide, yet its origins remain unknown. Androgens are implicated in the development of PCOS, but the decisive, invasive studies needed to confirm and elucidate their roles are not feasible in women. Hence, using our innovative mouse models of androgen resistant female mice, this study will determine the role of androgens in PCOS aiming to better understand, and identify new treatments for this common female reproductive disorder.
The Sexual Health And Attitudes Of Australian Prisoners
Funder
National Health and Medical Research Council
Funding Amount
$1,605,706.00
Summary
The second Sexual Health and Attitudes of Australian Prisoners study will be the largest population-based survey of prisoners’ sexual health, attitudes and behaviour undertaken in Australia. it has been nearly 10 years since the first survey. The 2nd survey will expand survey coverage and examine vulnerable prisoner subgroup, and provide up-to-date evidence essential to sexual and reproductive health policy and practice for this growing and disadvantaged population.
Using Genomics To Understand And Interrupt Transmission Of Sexually Transmitted Pathogens In Australia
Funder
National Health and Medical Research Council
Funding Amount
$798,714.00
Summary
Prevention and control of STIs in the 21st century requires timely, effective and high-resolution investigations which may be provided by genomic technologies. Building on existing datasets and expertise, we will provide a blueprint for genomics-based tracking of bacterial STIs in Australia, including the translation of this information to effect novel targeted public health actions, including screening, monitoring for outbreaks, and focused interventions to enhance control.
Evaluation Of Chlamydia Trachomatis Treatment Failure: A Cohort Study Of Women
Funder
National Health and Medical Research Council
Funding Amount
$761,844.00
Summary
Chlamydia is a very common sexually transmissible infection in Australia that can lead to infertility in women. About 4% of young adults have it. There is increasing concern by experts about the efficacy of the recommended chlamydia treatment. This is further supported by very high repeat infection rates following a previous positive chlamydia diagnosis. This study will measure whether chlamydia treatment failure is a problem and if so, this will change treatment guidelines worldwide.
Monogamy As An HIV And STI Prevention Strategy For Gay Men
Funder
National Health and Medical Research Council
Funding Amount
$407,506.00
Summary
Monogamy is relatively common among Australian gay men and yet relatively under researched or explored. At present we know little about the motivations of Australian gay men to enter and maintain monogamous relationships. This study will bring into clear view a phenomenon, and social and intimate practice, that has been almost entirely overlooked and will significantly advance our understanding of the dynamics of gay men's sexual behaviour and sexual cultures.
Sexual And Reproductive Health And Behaviours Of Young Offenders (14-18 Years) In NSW & Qld
Funder
National Health and Medical Research Council
Funding Amount
$869,730.00
Summary
Young Indigenous and non-Indigenous offenders in Australia aged 14 and 15 years have never been systematically surveyed regarding their sexual and reproductive health in Australia. Thus we have little information on which to base education and policy initiatives. To address this knowledge gap we will systematically survey young people in contact with the juvenile justice system aged 14-18 years to provide a comprehensive picture of their sexual and reproductive behaviours and needs.
Can Preventive Care Activities In General Practice Be Sustained When Financial Incentives And External Audit Plus Feedback Are Removed? A Randomised Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$1,201,443.00
Summary
There is increasing debate about the effectiveness of incentive payments and audit plus feedback on the clinical behaviour of general practitioners (GPs). Governments both in Australia and the UK are raising the threshold targets for payment eligibility making it more difficult for GPs to get payments. We will conduct a trial that will investigate the impact of removing financial incentives and/or external audit plus feedback on the preventive care activities of GPs.
Chromatin Dynamics During Sexual Differentiation In The Malaria Parasite P. Falciparum
Funder
National Health and Medical Research Council
Funding Amount
$535,858.00
Summary
Inhibiting malaria transmission is a critical step towards global eradication of this deadly disease. This proposal aims to understand the mechanisms regulating the expression of genes which control the differentiation of the transmission stages of malaria parasites. Such pathways are prime targets for novel anti-malarial drugs.
Disorders of sexual development are amongst the most common birth defects in humans. These conditions have profound consequences for the physical and psychological health of affected individuals. The incidence of these disorders is on the rise, and this has been linked to our increased exposure to chemicals in the environment that affect how our hormones function. This project will investigate how these chemicals affect hormonal pathways that control early development.