Polymer nanoparticles and their assembled supracolloidal monolithic structures for applications in separation science. This project will generate new polymeric materials that will improve the analysis of complex samples. This will be applied in a wide range of areas of national importance including: pharmaceutical analysis and drug discovery; environmental, clinical and forensic analysis; and energy generation and foods.
Pre-blast screening of improvised explosive devices - a National counter-terrorism initiative. The proposed research is focused on the specific needs of Australian counter-terrorism interests, including those of border protection, the customs service, transport authorities, forensic laboratories, etc. The support of this proposal will ensure that Australia, and its States and Territories are protected against terrorist threats. The support provided by the collaborating organisations from the var ....Pre-blast screening of improvised explosive devices - a National counter-terrorism initiative. The proposed research is focused on the specific needs of Australian counter-terrorism interests, including those of border protection, the customs service, transport authorities, forensic laboratories, etc. The support of this proposal will ensure that Australia, and its States and Territories are protected against terrorist threats. The support provided by the collaborating organisations from the various Federal and State police and forensic agencies, and the customs service, etc, highlights the importance of this project to the nation. Finally, a PhD student and a research assistant will be involved with the project and will gain specialised skills positioning them to make strong contributions to Australia's counter-terrorism measures.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0883096
Funder
Australian Research Council
Funding Amount
$600,000.00
Summary
Analytical and Preparative Enantioselective Chromatography. Enantiomers are forms of the same molecule that are non-superimposable mirror images of one another, like a left hand and a right hand. Because they are so similar they are very difficult to separate. However, they have very different biological properties, such as when used as drugs. One enantiomer may be beneficial while the other has no effect or sometimes is even toxic. Therefore it is important to be able to tell how much of ea ....Analytical and Preparative Enantioselective Chromatography. Enantiomers are forms of the same molecule that are non-superimposable mirror images of one another, like a left hand and a right hand. Because they are so similar they are very difficult to separate. However, they have very different biological properties, such as when used as drugs. One enantiomer may be beneficial while the other has no effect or sometimes is even toxic. Therefore it is important to be able to tell how much of each enantiomer is present in a sample and to be able to separate them. This facility will allow us to do both of these things.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0882836
Funder
Australian Research Council
Funding Amount
$160,000.00
Summary
A novel isotope facility to characterise high-molecular-weight fractions of natural organic matter in soils, sediments, water, petroleum and coal. This facility will improve our ability to forecast environmental responses to future climate change, and help Australia manage current threats to its biodiversity. Furthermore, this research will increase the ability to identify crude oil sources, to the benefit of petroleum exploration in Australia. This facility will also contribute to an improved u ....A novel isotope facility to characterise high-molecular-weight fractions of natural organic matter in soils, sediments, water, petroleum and coal. This facility will improve our ability to forecast environmental responses to future climate change, and help Australia manage current threats to its biodiversity. Furthermore, this research will increase the ability to identify crude oil sources, to the benefit of petroleum exploration in Australia. This facility will also contribute to an improved understanding of controls on water quality and will help to protect our precious freshwater resources, already under intense pressure from climate change. Importantly, this project will enable students and young professionals to be trained in state-of-the-art technology, leading to quality scientists ready for employment in industry.
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On-site and comprehensive technology for chemical weapons, toxins and drugs. This project aims to evaluate and validate broad capabilities of advanced chemical profiling using benchtop and portable gas chromatography–mass spectrometry for forensic applications. Establishing guidelines for sampling various matrices, key performance measures, and improving chemical and residue identification for drug profiling in clandestine laboratories and public venues, chemical warfare agents, and chemical tox ....On-site and comprehensive technology for chemical weapons, toxins and drugs. This project aims to evaluate and validate broad capabilities of advanced chemical profiling using benchtop and portable gas chromatography–mass spectrometry for forensic applications. Establishing guidelines for sampling various matrices, key performance measures, and improving chemical and residue identification for drug profiling in clandestine laboratories and public venues, chemical warfare agents, and chemical toxins is expected. Anticipated outcomes for project partners in defence and policing include detailed knowledge of sample and residue composition and on-site assessment of chemical risks with immediate feedback. Benefits should include improved community and security services safety by enhanced detection of harmful substances.Read moreRead less
Oxidation product generation during heating and storage of bio-fuels and alternative fuels assessed by multidimensional gas chromatography. Renewable bio-fuels offer much promise as a replacement for fossil fuels. However, they have a tendency to oxidise when prepared and used, potentially forming gums and solid deposits in engines. The objective of this project is the identification of these deposits and subsequent prevention during engine operation.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE180100180
Funder
Australian Research Council
Funding Amount
$299,105.00
Summary
Gas chromatography: separating inseparables, identifiying unidentifiables. This project aims to provide researchers with an integrated capability for separation, isolation, and precise structural identification of volatile compounds. It expects to deliver a systematic solution using unprecedented, automated multidimensional gas chromatographic separation, isolating pure compounds for off-line characterisation using appropriate spectroscopic tools, for example nuclear magnetic resonance. This wi ....Gas chromatography: separating inseparables, identifiying unidentifiables. This project aims to provide researchers with an integrated capability for separation, isolation, and precise structural identification of volatile compounds. It expects to deliver a systematic solution using unprecedented, automated multidimensional gas chromatographic separation, isolating pure compounds for off-line characterisation using appropriate spectroscopic tools, for example nuclear magnetic resonance. This will provide significant benefits, such as permitting traceability of (bio)-synthetic pathways, better characterise chemical signalling in plants, accelerate identification of advanced intermediates required for total synthesis of alkaloids, improve detection of metabolites, and determine interactions between small allergens and proteins.Read moreRead less
The evolution of specialised orchid pollination and its reversibility. This project aims to determine the changes in key floral volatile compounds underpinning pollination transitions, identify their molecular basis, and understand the ecological processes favouring reversals away from extreme specialisation. By focusing on pollination of sexually deceptive Australian orchids, this project would be the first to determine the molecular, chemical and behavioural basis of evolutionary reversals to ....The evolution of specialised orchid pollination and its reversibility. This project aims to determine the changes in key floral volatile compounds underpinning pollination transitions, identify their molecular basis, and understand the ecological processes favouring reversals away from extreme specialisation. By focusing on pollination of sexually deceptive Australian orchids, this project would be the first to determine the molecular, chemical and behavioural basis of evolutionary reversals to more generalised strategies in a group of plants facing high risk of pollinator extinction. The expected outcome, a mechanistic understanding of how pollination transitions occur, would be internationally ground-breaking, and provide crucial insights to protect this diverse but highly threatened group of plants.Read moreRead less