Pore Engineering of Chromatography Membranes for Bioseparation. Protein separation and purification is an essential unit operation in manufacturing processes of therapeutic proteins. The project aims to advance the practical applications of chromatography membrane, an emerging technology for protein separation and purification, by tailoring membrane pore geometry and surface functionality to achieve enhanced separation performance. The project expects to generate advanced knowledge and technique ....Pore Engineering of Chromatography Membranes for Bioseparation. Protein separation and purification is an essential unit operation in manufacturing processes of therapeutic proteins. The project aims to advance the practical applications of chromatography membrane, an emerging technology for protein separation and purification, by tailoring membrane pore geometry and surface functionality to achieve enhanced separation performance. The project expects to generate advanced knowledge and techniques in the fields of reactive polymer synthesis, functional membrane fabrication and application in bioseparation. The innovative membranes developed in the project are able to improve the production capacity of therapeutic protein manufacturing processes, providing significant economic benefits to Australia.Read moreRead less
New hyphenated chromatographic and spectroscopic methods for oil analysis. This project aims to use novel chemical separation methods combined with spectroscopy to identify useful markers in olive oil and essential oil to ensure purity, quality and authenticity, which are all ongoing issues in these industries in Australia and overseas. The project plans to compare and integrate results of multidimensional gas chromatography combined with mass spectrometry and Fourier transform infrared analyses ....New hyphenated chromatographic and spectroscopic methods for oil analysis. This project aims to use novel chemical separation methods combined with spectroscopy to identify useful markers in olive oil and essential oil to ensure purity, quality and authenticity, which are all ongoing issues in these industries in Australia and overseas. The project plans to compare and integrate results of multidimensional gas chromatography combined with mass spectrometry and Fourier transform infrared analyses with data libraries to generate precise molecular identification. The outcome is expected to help monitor adulteration of oils and maintain the high quality standards of Australian produce.Read moreRead less
Industrial biotechnology for improved manufacture of medicinal alkaloids. Industrial biotechnology for improved manufacture of medicinal alkaloids. This project aims to develop a new semi-synthetic route for the manufacture of Codeine from Thebaine. Codeine is manufactured by the chemical conversion of poppy-derived Morphine, which is low yielding and environmentally unfriendly. This project will investigate and optimise two key enzymes in the biosynthetic pathway to Codeine and develop an innov ....Industrial biotechnology for improved manufacture of medicinal alkaloids. Industrial biotechnology for improved manufacture of medicinal alkaloids. This project aims to develop a new semi-synthetic route for the manufacture of Codeine from Thebaine. Codeine is manufactured by the chemical conversion of poppy-derived Morphine, which is low yielding and environmentally unfriendly. This project will investigate and optimise two key enzymes in the biosynthetic pathway to Codeine and develop an innovative bioreactor to achieve high yield. It will research industrial biotransformations, providing a greener and cheaper process for increased global access to Codeine. Australian opiate manufacturing is expected to benefit from value adding and increased flexibility introduced by a biotechnology approach.Read moreRead less
Optimising dissolved air flotation (DAF) for algae removal by bubble modification in drinking water and advanced wastewater systems. Algal blooms in potable water reservoirs and advanced wastewater treatment lagoons can impact the performance and economic viability of water treatment processes resulting in taste and odour episodes and the risk of algal toxins as well as causing further limitation to already stressed water resources in Australia. This project aims to develop an adaptation of the ....Optimising dissolved air flotation (DAF) for algae removal by bubble modification in drinking water and advanced wastewater systems. Algal blooms in potable water reservoirs and advanced wastewater treatment lagoons can impact the performance and economic viability of water treatment processes resulting in taste and odour episodes and the risk of algal toxins as well as causing further limitation to already stressed water resources in Australia. This project aims to develop an adaptation of the dissolved air flotation process that is already used for algae treatment that will provide a more robust, economic and sustainable barrier to algal cells in accordance with the Australian Drinking and Recycled Water Guidelines.Read moreRead less
Improving determinants of Australian sports talent identification and development: a multi-disciplinary approach. Sport is important to many Australians. Our sport successes enhance our national identity, generate community pride and attract mega sport events. Currently our sport talent identification and development (TID) systems have been surpassed by our international rivals who borrowed from and improved our knowledge. This project will help regain Australia's international advantage and aga ....Improving determinants of Australian sports talent identification and development: a multi-disciplinary approach. Sport is important to many Australians. Our sport successes enhance our national identity, generate community pride and attract mega sport events. Currently our sport talent identification and development (TID) systems have been surpassed by our international rivals who borrowed from and improved our knowledge. This project will help regain Australia's international advantage and again make Australian TID the international benchmark. Results will highlight the role of TID practices in improving recreational participation and maximising, attracting, developing and retaining sport talent. This will result in improved use of sports limited TID funding by providing greater understanding of factors that influence elite selection and sport development.Read moreRead less
Developing a novel carbon negative fertiliser . Food security is vital to support our growing population. However, our increasing reliance on intensive farming systems necessitates increased fertiliser use, leading to increased water pollution and soil degradation - threatening both the Australian environment and food security. Increasing carbon storage capacity by soil and decreasing fertiliser use are two of the primary pathways for restoring the bio-support capacity of soils and reducing farm ....Developing a novel carbon negative fertiliser . Food security is vital to support our growing population. However, our increasing reliance on intensive farming systems necessitates increased fertiliser use, leading to increased water pollution and soil degradation - threatening both the Australian environment and food security. Increasing carbon storage capacity by soil and decreasing fertiliser use are two of the primary pathways for restoring the bio-support capacity of soils and reducing farming footprints. This innovative and first-of-its-kind project aims to develop a cost-effective, carbon negative fertiliser that reduces fertiliser inputs and increases soil carbon storageRead moreRead less
Toward inclusive peace. Toward inclusive peace. This project will investigate how peace agreements can advance women’s rights and participation after post-conflict and political transitions. It will examine the relationship between women’s presence in peacemaking processes, women’s rights and gender provisions in peace agreements, and women’s participation in post-conflict governance of countries with successful peace agreements. Women’s participation in peace processes makes a successful peace ....Toward inclusive peace. Toward inclusive peace. This project will investigate how peace agreements can advance women’s rights and participation after post-conflict and political transitions. It will examine the relationship between women’s presence in peacemaking processes, women’s rights and gender provisions in peace agreements, and women’s participation in post-conflict governance of countries with successful peace agreements. Women’s participation in peace processes makes a successful peace agreement likelier, but may not consolidate peace or lead to greater participation by women in the governance of the country. Anticipated outcomes are analysis of the relationship between peace processes and gender equality in conflict-affected societies; improved consular delivery of aid programmes in fragile states; and targeted air delivery that empowers women.Read moreRead less
Optimal management of coastal ecosystems for blue carbon sequestration. Optimal management of coastal ecosystems for blue carbon sequestration. This project aims to develop decision tools to predict how different management plans could affect the persistence of coastal ecosystems and their capacity to sequester carbon. Coastal ‘blue carbon’ ecosystems (seagrasses, saltmarshes, mangroves) are among Earth’s most efficient carbon sinks, but coastal development and climate change threaten their capa ....Optimal management of coastal ecosystems for blue carbon sequestration. Optimal management of coastal ecosystems for blue carbon sequestration. This project aims to develop decision tools to predict how different management plans could affect the persistence of coastal ecosystems and their capacity to sequester carbon. Coastal ‘blue carbon’ ecosystems (seagrasses, saltmarshes, mangroves) are among Earth’s most efficient carbon sinks, but coastal development and climate change threaten their capacity to sequester carbon. Resource managers urgently need guidance to manage coasts to minimise carbon losses and maximise gains. This project is expected to develop knowledge of how to manage blue carbon ecosystems to achieve maximum carbon sequestration capacity, and to put Australia at the forefront of international efforts to incorporate coastal carbon within carbon dioxide mitigation strategies.Read moreRead less
Nurturing Australia's Little Multilingual Minds. Despite its substantial multilingual capacity of more than 300 languages, Australia has been described as a 'graveyard for languages'. In partnering with community organisations we will facilitate polyglot early learning, commencing with Spanish and Vietnamese. Expected outcomes are a deep understanding of multilingual families’ experiences, a model to support lifespan multilingual education, and openly-accessible database of child language in her ....Nurturing Australia's Little Multilingual Minds. Despite its substantial multilingual capacity of more than 300 languages, Australia has been described as a 'graveyard for languages'. In partnering with community organisations we will facilitate polyglot early learning, commencing with Spanish and Vietnamese. Expected outcomes are a deep understanding of multilingual families’ experiences, a model to support lifespan multilingual education, and openly-accessible database of child language in heritage languages. Benefits include a pivotal contribution to early childhood education with the creation of a tailor-made, principle-based program, which will enhance children’s academic achievement, familial social and mental wellbeing, and cultural and economic opportunities for all Australians. Read moreRead less
A Wearable Motion Analysis System: Novel Clinical and Research Applications. Because the biomechanical analysis of human motion is confined to the laboratory, it often has restricted applicability. This is a recognized limitation, because laboratory studies cannot capture the true picture of how individuals move under conditions encountered during daily living. Consequently there are many situations where a more complete and realistic knowledge of biomechanics would be significant advantage such ....A Wearable Motion Analysis System: Novel Clinical and Research Applications. Because the biomechanical analysis of human motion is confined to the laboratory, it often has restricted applicability. This is a recognized limitation, because laboratory studies cannot capture the true picture of how individuals move under conditions encountered during daily living. Consequently there are many situations where a more complete and realistic knowledge of biomechanics would be significant advantage such as in the diagnosis, treatment and rehabilitation of movement disorders and injuries. The research project described in this proposal would for the first time, obtain comprehensive biomechanical data outside the laboratory using a fully integrated wearable motion analysis system.Read moreRead less