Selective enrichment of proteins using micro-Gradiflow technology and characterisation of proteins using LC-MS/MS. This project describes crucial areas for the technology development of protein enrichment and fractionation. While current techniques are powerful, the usefulness to identify and characterise proteins of low abundance from massively complex samples in the presence of abundant proteins is limited and requires up to mililitre volumes. We intend to develop the micro-Gradiflow technolog ....Selective enrichment of proteins using micro-Gradiflow technology and characterisation of proteins using LC-MS/MS. This project describes crucial areas for the technology development of protein enrichment and fractionation. While current techniques are powerful, the usefulness to identify and characterise proteins of low abundance from massively complex samples in the presence of abundant proteins is limited and requires up to mililitre volumes. We intend to develop the micro-Gradiflow technology in association with Gradipore as a means of protein fractionation using microlitre volumes of sample. This technology will be applicable to all areas of proteomic research and in particular to the study of cell differentiation. The outcome for Australian industry, our competitiveness both industrial and scientific, and the potential for economic advancement is tremendous.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE150101687
Funder
Australian Research Council
Funding Amount
$340,000.00
Summary
Nanostructure Tailoring of Inorganic Membranes by Rapid Thermal Processing. This project aims to produce inorganic membranes with desired nanostructures using a Rapid Thermal Processing (RTP) technique for gas separation applications. The key concept of the research is that the RTP will be able to achieve thin-film membrane layer with a finer microstructure and pore size control without heat stress-induced cracking. RTP aims to deliver superior membrane performance with less than 10 per cent of ....Nanostructure Tailoring of Inorganic Membranes by Rapid Thermal Processing. This project aims to produce inorganic membranes with desired nanostructures using a Rapid Thermal Processing (RTP) technique for gas separation applications. The key concept of the research is that the RTP will be able to achieve thin-film membrane layer with a finer microstructure and pore size control without heat stress-induced cracking. RTP aims to deliver superior membrane performance with less than 10 per cent of the fabrication time compared to normal slow calcination. The outcomes of this new technology aims to make inorganic membranes a commercial reality and maximize the membrane manufacturing capability and productivity of petrochemcial, chemical and clean coal/energy industries.Read moreRead less
Optimising nanofiltration and reverse osmosis filtration processes for water recycling: effects of fouling and chemical cleaning on trace contaminant removal. In Australia, water recycling is considered a principal measure to manage the current ongoing water shortage and to better protect the environment. Membrane filtration processes play important roles in the treatment of reclaimed municipal wastewater. However, there is very limited knowledge regarding the reliability of such processes in re ....Optimising nanofiltration and reverse osmosis filtration processes for water recycling: effects of fouling and chemical cleaning on trace contaminant removal. In Australia, water recycling is considered a principal measure to manage the current ongoing water shortage and to better protect the environment. Membrane filtration processes play important roles in the treatment of reclaimed municipal wastewater. However, there is very limited knowledge regarding the reliability of such processes in removing trace contaminants from recycled water, which may result in unintended health consequences. This research will lead to a comprehensive understanding of the removal process of such contaminants by membrane filtration. Consequently, the likely avenue of risk can be eliminated and the treatment process can be optimised to achieve economic savings and environmental protection.Read moreRead less
Optimising Removal of Proteinaceous Foulants from Membranes. Removal of proteinacous foulants from membrane systems imposes both significant economic costs in terms of chemical usage as well as significant environmental costs in terms of water usage and production of effluents from the cleaning and rinsing waters. The outcome of this project should allow us to develop methods for the prediction and optimisation of membrane cleaning performance of relevance to major Australian industries includin ....Optimising Removal of Proteinaceous Foulants from Membranes. Removal of proteinacous foulants from membrane systems imposes both significant economic costs in terms of chemical usage as well as significant environmental costs in terms of water usage and production of effluents from the cleaning and rinsing waters. The outcome of this project should allow us to develop methods for the prediction and optimisation of membrane cleaning performance of relevance to major Australian industries including the dairy, food processing and water and waste water treatment industries.Read moreRead less
Optimisation of nutrient removal, membrane fouling and sludge dewatering in hybrid coagulation/submerged membrane bioreactor treatment of wastewaters. Submerged membrane bioreactor technology for the treatment of wastewaters is now a competitive technology with small footprint and generally high quality of treated effluent. Despite this, challenges remain in ensuring low effluent nutrient concentrations, minimal membrane fouling and acceptable excess sludge dewaterability. Addition of iron or a ....Optimisation of nutrient removal, membrane fouling and sludge dewatering in hybrid coagulation/submerged membrane bioreactor treatment of wastewaters. Submerged membrane bioreactor technology for the treatment of wastewaters is now a competitive technology with small footprint and generally high quality of treated effluent. Despite this, challenges remain in ensuring low effluent nutrient concentrations, minimal membrane fouling and acceptable excess sludge dewaterability. Addition of iron or aluminium-based coagulant chemicals can assist but many uncertainties with regard to choice of chemical, optimal dosing arrangements and membrane bioreactor operating conditions remain. Experimental and computational studies targeted at improving understanding and optimising performance will be undertaken through collaborative studies by the UNSW and Tsinghua University (Beijing) research team.Read moreRead less
Optimising dissolved air flotation (DAF) for algae removal by bubble modification in drinking water and advanced wastewater systems. Algal blooms in potable water reservoirs and advanced wastewater treatment lagoons can impact the performance and economic viability of water treatment processes resulting in taste and odour episodes and the risk of algal toxins as well as causing further limitation to already stressed water resources in Australia. This project aims to develop an adaptation of the ....Optimising dissolved air flotation (DAF) for algae removal by bubble modification in drinking water and advanced wastewater systems. Algal blooms in potable water reservoirs and advanced wastewater treatment lagoons can impact the performance and economic viability of water treatment processes resulting in taste and odour episodes and the risk of algal toxins as well as causing further limitation to already stressed water resources in Australia. This project aims to develop an adaptation of the dissolved air flotation process that is already used for algae treatment that will provide a more robust, economic and sustainable barrier to algal cells in accordance with the Australian Drinking and Recycled Water Guidelines.Read moreRead less
The Development of New Carrier Technologies for Spray-Dried Fruit Extracts. This project aims to develop new carrier techniques for spray drying fruit extracts based on the use of natural fibres, with the aim of overcoming a key problem in the operation of spray dryers for producing powders, the deposition of particles on walls. Carriers are non-sticky materials that effectively dilute the stickiness of any materials. The significance is that it will use waste products from fruit processing (th ....The Development of New Carrier Technologies for Spray-Dried Fruit Extracts. This project aims to develop new carrier techniques for spray drying fruit extracts based on the use of natural fibres, with the aim of overcoming a key problem in the operation of spray dryers for producing powders, the deposition of particles on walls. Carriers are non-sticky materials that effectively dilute the stickiness of any materials. The significance is that it will use waste products from fruit processing (the fibres from skins) to overcome this problem, and it will also be possible to dry sticky materials using material from the fruit itself, rather than additives such as maltodextrin.Read moreRead less
Characterisation and Treatment of Reverse Osmosis Concentrates from Water Recycling Applications. Concentrates from reverse osmosis (RO) pose a considerable threat to both the environment but also the successful implementation of reverse osmosis as a technology. Naturally, the concentrate contains everything that the RO retains and hence contaminants such as viruses, organics such as pharmaceutically active compounds and hormones as well as nutrients and salinity. Treatment of such waste streams ....Characterisation and Treatment of Reverse Osmosis Concentrates from Water Recycling Applications. Concentrates from reverse osmosis (RO) pose a considerable threat to both the environment but also the successful implementation of reverse osmosis as a technology. Naturally, the concentrate contains everything that the RO retains and hence contaminants such as viruses, organics such as pharmaceutically active compounds and hormones as well as nutrients and salinity. Treatment of such waste streams will enhance the health of receiving water bodies and reduce the risk of increased build up of contaminants if wastes are recycled into wastewater treatment plants. New ways to treat such contaminants will be explored, the efficiency and cost evaluated in the broader water cycle and sustainability framework.Read moreRead less
Flotation separation of nanoparticles. This project deals with the separation of fine nanoparticles suspended in water, by attachment to small gas bubbles. It aims to find a way of removing nanoparticles from water, or of separating one species from another. The process could be used for simple solids such as metal oxides, and for biological materials such as large molecules, viruses and small bacteria. The work will be both theoretical and experimental. This ground-breaking project will build u ....Flotation separation of nanoparticles. This project deals with the separation of fine nanoparticles suspended in water, by attachment to small gas bubbles. It aims to find a way of removing nanoparticles from water, or of separating one species from another. The process could be used for simple solids such as metal oxides, and for biological materials such as large molecules, viruses and small bacteria. The work will be both theoretical and experimental. This ground-breaking project will build upon past successes of the applicant, whose invention in the field of resource recovery is contributing close to $1 billion a year to Australia's exports.Read moreRead less
Development of High Performance Nanocomposite Filtration Membranes: Fabrication and Fouling Mechanisms. This project will develop high performance membranes for the filtration of water and wastewater using novel nanotechnology processes. This will reduce the costs and environmental impact of water treatment and risk from low-level chemical contaminants such as micropollutants. The project will also provide an enhanced technology base for producing low cost, hybrid inorganic-organic materials fo ....Development of High Performance Nanocomposite Filtration Membranes: Fabrication and Fouling Mechanisms. This project will develop high performance membranes for the filtration of water and wastewater using novel nanotechnology processes. This will reduce the costs and environmental impact of water treatment and risk from low-level chemical contaminants such as micropollutants. The project will also provide an enhanced technology base for producing low cost, hybrid inorganic-organic materials for widespread environmental, agricultural and food applications.Read moreRead less