Engineering and expression of recombinant antibodies that interact with plant pathogenic phytoplasma membrane proteins - a model for phytoplasma disease management. . In Australia phytoplasmas are associated with serious diseases including papaya dieback and strawberry lethal yellows. Phytoplasmas cannot be cultured so there is a paucity of knowledge at the genomic level. We have identified the ABC Transporter and FtsH genes and expressed these phytoplasma membrane proteins (MP) in E. coli . We ....Engineering and expression of recombinant antibodies that interact with plant pathogenic phytoplasma membrane proteins - a model for phytoplasma disease management. . In Australia phytoplasmas are associated with serious diseases including papaya dieback and strawberry lethal yellows. Phytoplasmas cannot be cultured so there is a paucity of knowledge at the genomic level. We have identified the ABC Transporter and FtsH genes and expressed these phytoplasma membrane proteins (MP) in E. coli . We will generate antibody fragments that bind these MP and express them in tomato. We will analyse antibody expression in tomato and study their association with the phytoplasma membrane. Transgenic plants will be inoculated with phytoplasma and monitored for resistance. This work represents a major step towards engineering resistance to phytoplasmas.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989147
Funder
Australian Research Council
Funding Amount
$950,000.00
Summary
Advanced high throughput genomics facility for biological, medical, agricultural, environmental and evolutionary research. Infrastructure requested will expand the capacity of researchers in NSW/NT to undertake environmental, medical and evolutionary studies using state-of-the-art technologies based on the recent advances in DNA sequencing analyses. It will ensure the retention of leading researchers in the exciting areas of genomics and Systems Biology and make a significant contribution to bi ....Advanced high throughput genomics facility for biological, medical, agricultural, environmental and evolutionary research. Infrastructure requested will expand the capacity of researchers in NSW/NT to undertake environmental, medical and evolutionary studies using state-of-the-art technologies based on the recent advances in DNA sequencing analyses. It will ensure the retention of leading researchers in the exciting areas of genomics and Systems Biology and make a significant contribution to biomolecular research in medicine, agriculture and environmental biology, thereby providing major benefits to the wider community. The application will enhance existing genomic technologies by substantially increasing the scope of experiments that can be performed leading to important advances in gene discovery.Read moreRead less
3D printing of custom musical instruments for heritage and industry needs. This Project will explore innovative heritage and commercial applications for the 3D modelling and printing of custom musical instruments to advance Australia’s flexible-manufacturing industry. Musical instruments are complex devices, often made with multiple parts and/or materials, that are commonly built to produce sound through a multitude of manufacturing processes to meet high-performance requirements. When hand-craf ....3D printing of custom musical instruments for heritage and industry needs. This Project will explore innovative heritage and commercial applications for the 3D modelling and printing of custom musical instruments to advance Australia’s flexible-manufacturing industry. Musical instruments are complex devices, often made with multiple parts and/or materials, that are commonly built to produce sound through a multitude of manufacturing processes to meet high-performance requirements. When hand-crafted, they can present considerable morphological variations, even within a single instrument type. The Project’s novel challenge of flexibly manufacturing custom music instruments to meet a diversity of end-user needs will create new digital heritage strategies and market opportunities for Australian research end-users.Read moreRead less
Virtual Galleries: new media technologies to influence livelihood and arts participation in remote communities of the Northern Territory, Australia. The Virtual Galleries project addresses the issue of limited economic development in remote communities by introducing a user-controlled webcam and interactive 3-D (three-dimensional) Art Galleries into remote art centres to help people in remote communities to secure an income and create wealth and social wellbeing for themselves, their families an ....Virtual Galleries: new media technologies to influence livelihood and arts participation in remote communities of the Northern Territory, Australia. The Virtual Galleries project addresses the issue of limited economic development in remote communities by introducing a user-controlled webcam and interactive 3-D (three-dimensional) Art Galleries into remote art centres to help people in remote communities to secure an income and create wealth and social wellbeing for themselves, their families and their communities.Read moreRead less
Investing in Aboriginal Languages. We will develop the first systematic account of Aboriginal language programs and what makes them effective and sustainable. The project will create a substantial evidence base, leading to a comprehensive model of language revitalisation and how it operates in each place, and for whom. The model will show how local and national organisations can invest in Aboriginal languages, and what kinds of returns they can expect. The project involves a two-way collaboratio ....Investing in Aboriginal Languages. We will develop the first systematic account of Aboriginal language programs and what makes them effective and sustainable. The project will create a substantial evidence base, leading to a comprehensive model of language revitalisation and how it operates in each place, and for whom. The model will show how local and national organisations can invest in Aboriginal languages, and what kinds of returns they can expect. The project involves a two-way collaboration with Aboriginal people across the country that will elevate their voices and build their capacity for designing and evaluating programs, businesses and technologies for keeping Aboriginal languages strong.Read moreRead less
Digital noticeboards for remote Aboriginal communities: bringing web 2.0 participation to non-western cultures with low English and technical literacy. Remote Aboriginal communities suffer from geographic and cultural isolation. Web 2.0 offers a solution yet is ill-suited to traditional collective cultures, those with low English and technical literacy, and the poor. This project will produce novel public web-enabled touchscreen noticeboards and table tops suited to traditional cultures.