Creating Treatment Options For Endometrial Cancer Through High-level Clinical Trials
Funder
National Health and Medical Research Council
Funding Amount
$2,508,156.00
Summary
Endometrial cancer (EC) arises from the inner lining of the womb. Treatment typically involves surgery (hysterectomy) to remove the womb and explore if cancer has affected the lymph glands in the pelvis. The benefit of surgery on the lymph glands is doubtful. My research program will generate evidence to inform clinical practice on the treatment of EC and explore non-surgical treatment alternatives to a hysterectomy for better patient outcomes, particularly in women who wish to start a family.
Early Career Industry Fellowships - Grant ID: IE230100441
Funder
Australian Research Council
Funding Amount
$474,443.00
Summary
Sounds of change: using ecological knowledge to advance acoustic monitoring. To recover biodiversity, conservation actions must be informed by robust ecological data. In partnership with Bush Heritage Australia, this project aims to transform ecological monitoring with eco-acoustic technologies by developing new acoustic metrics to measure biodiversity at various levels, from individual species through to whole communities. This project will combine advanced computer methods with theories of ani ....Sounds of change: using ecological knowledge to advance acoustic monitoring. To recover biodiversity, conservation actions must be informed by robust ecological data. In partnership with Bush Heritage Australia, this project aims to transform ecological monitoring with eco-acoustic technologies by developing new acoustic metrics to measure biodiversity at various levels, from individual species through to whole communities. This project will combine advanced computer methods with theories of animal sounds and communities to generate metrics that are informed by animal ecology and directly address monitoring needs of conservation organisations. By experimentally testing the metrics on long-duration real-world sound data, this project will provide new tools to measure conservation impact and prioritise actions.Read moreRead less
Status Of Australian Fish Stocks (SAFS) Reports 2020, And Further Development Of The SAFS Production And Dissemination System
Funder
Fisheries Research and Development Corporation
Funding Amount
$1,383,901.12
Summary
The current application is to produce the SAFS reports in 2020 and address strategic issues outlined above. In order to ensure the continuation of SAFS beyond 2020, it is essential for jurisdictions to develop ownership of the reports and to embed SAFS processes in core business, and for efficiencies in production and report management to continue to progress. A parallel project to develop jurisdictional reporting services is also underway to assist jurisdiction develop their jurisdictional chap ....The current application is to produce the SAFS reports in 2020 and address strategic issues outlined above. In order to ensure the continuation of SAFS beyond 2020, it is essential for jurisdictions to develop ownership of the reports and to embed SAFS processes in core business, and for efficiencies in production and report management to continue to progress. A parallel project to develop jurisdictional reporting services is also underway to assist jurisdiction develop their jurisdictional chapters. As documented in the independent audit of SAFS 2016 (FRDC project 2016-143), the process of compiling SAFS on a co-operative basis between FRDC, Australian government agencies and all fisheries jurisdictions has led to greater joint collaboration, as well as transfers of methodologies and processes, to deliver higher quality and more credible stock status reporting which can be accessed nationally and internationally, as well as assisting in policy decisions regarding changes to particular fisheries management arrangements and in research priorities. Primary drivers for National reporting of the SAFS include: (i) the State of the Environment Report 2011, i.e., ‘lack of a nationally integrated approach inhibits effective marine management’; (ii) a recommendation of the House of Representatives Inquiry into the Role of Science for Fisheries and Aquaculture (Netting the Benefits Report 2012), i.e., ‘producing national status report regularly’; (iii) the Australian Fisheries Management Forum national statement of intent, i.e. a key outcome of ‘Goal 1’ is the National Status of Australian Fish Stocks Report; (iv) the National Fishing and Aquaculture Strategy 2015–20, i.e., ‘Goal 1’ of this strategy will be partially measured by an increased number of fisheries assessed as environmentally sustainable in the Status of Australian Fish Stocks Reports (this includes reducing the number of stocks assessed as uncertain); (v) the FRDC RD&E Plan 2015–20, i.e., key targets for deliverables against National Priority One include (i) “Increase the number of species to 200 in the national Status of Australian Fish Stocks Reports” and (ii) “Reduce the number of species classified as ‘undefined’ from the current figure of approximately Objectives: 1. Continue to develop a set of robust and consistent national stock status reports and a strong sense of report ownership by jurisdictions 2. To produce a fifth edition of the SAFS reports in 2020 3. Increase the number of species in SAFS to provide a comprehensive coverage of species of interest to stakeholder groups that will refer to the reports for information on sustainability and management success. 4. Reduction in the number (percentage) of species classified as 'undefined' where possible using data-poor assessment methodology Read moreRead less
Examining The Relationship Between Fishery Recruitment, Essential Benthic Habitats And Environmental Drivers In Exmouth Gulf
Funder
Fisheries Research and Development Corporation
Funding Amount
$514,056.00
Summary
Stock status in the EGPMF is assessed by monitoring fishery-independent and fishery-dependent catch rates (used as indices of recruitment and spawning stock levels) relative to specified reference points. However, in recent years factors other than the spawning stock index appear to be responsible for low levels of prawn recruitment. Given recent indications that the distribution and abundance of seagrass habitats may influence prawn recruitment there is a need to better understand the rela .... Stock status in the EGPMF is assessed by monitoring fishery-independent and fishery-dependent catch rates (used as indices of recruitment and spawning stock levels) relative to specified reference points. However, in recent years factors other than the spawning stock index appear to be responsible for low levels of prawn recruitment. Given recent indications that the distribution and abundance of seagrass habitats may influence prawn recruitment there is a need to better understand the relationship between prawn recruitment, environmental conditions and habitats. Understanding these relationships is required to clarify the uncertainty around stock fluctuations and improve stock assessments. The information is also required so that management can be more cognisant of the impacts of environmental conditions on annual recruitment variability and implement adaptive management strategies, such as altering seasonal arrangements, to prevent overfishing.
Similarly, the recent MSC assessment of the EGPMF fishery has highlighted the need to clarify the uncertainty in fishery independent surveys and stock assessments including the influence of environmental factors on indices, and collect environmental and habitat data to detect changes in risk to habitat due to fishing including ongoing monitoring of critical habitat types.
Therefore, the development of broad scale fishery specific, cost effective monitoring techniques is essential to assess and monitor the association between critical fish habitats, environmental drivers and prawn recruitment. These techniques need to be developed at appropriate temporal and spatial scales to allow for early intervention of appropriate management measures, such as adjusting spatial and temporal closures, to ensure the long term sustainability of stocks and maintain MSC certification. Given that recruitment in a number of the State’s other invertebrate fisheries appears to be influenced by environmental drivers developing techniques to understand these relationships is a critical component of ensuring the management of WA’s fisheries resources is based on robust science.
Objectives: 1. Collate and review historical, satellite, habitat and environmental data for the Exmouth Gulf and Shark Bay ecosystems to identify factors that may influence recruitment. 2. Assess the ability of different techniques, at various spatial and temporal scales, to identify, assess and monitor critical fish habitat and environmental conditions which may affect recruitment patterns of prawns into the Exmouth Gulf Prawn Managed Fishery 3. Collect local environmental and productivity data to assess the feasibility of collecting broad scale data remotely. 4. Develop a cost effective monitoring program for critical fish habitat and environmental drivers which allows the development of mitigation measures to assist in alleviating poor recruitment events. Read moreRead less
Developing A Cost-efficient Stock Assessment Program For Southern Calamari Fisheries
Funder
Fisheries Research and Development Corporation
Funding Amount
$496,827.00
Summary
Southern Calamari are important to multiple commercial and community fishery sectors in SA. Southern Calamari are now managed using a TACC for the commercial MSF and have specified resource allocations for recreational, Aboriginal/Traditional, Charter Boat, GSV prawn and SG prawn fisheries. However, the current assessment program does not capture the importance of this species and cannot support the level of management required. The primary outcome of this project will be to develop an assessmen ....Southern Calamari are important to multiple commercial and community fishery sectors in SA. Southern Calamari are now managed using a TACC for the commercial MSF and have specified resource allocations for recreational, Aboriginal/Traditional, Charter Boat, GSV prawn and SG prawn fisheries. However, the current assessment program does not capture the importance of this species and cannot support the level of management required. The primary outcome of this project will be to develop an assessment program for Southern Calamari in SA that can be used to assign stock status and provide TACC setting advice to fisheries management.
Like many cephalopod assessments, the current SA Southern Calamari assessment is basic as scientific advances have not occurred at the same rate as advances for finfish or crustacean assessment methods. Therefore, the successful development of an assessment program for Southern Calamari in SA would provide a valuable scientific contribution to several other Australian squid fisheries as they often encounter similar assessment difficulties
Overcoming key knowledge gaps and incorporating information on environmental drivers will be a key focus of this project, in order to develop an assessment that accounts for the full complexity of cephalopod population dynamics. However, there are limited resources to undertake an assessment in SA as the commercial MSF has a low gross value product (GVP) but has high assessment needs across several species. Therefore, a cost-effective assessment program must be developed to allow for its regular application, which is necessary for short lived species such as Southern Calamari.
The proposed project will address two FRDC strategic plan outcomes (Growth for enduring prosperity, and best practices and production systems) by developing a best practice assessment program that can be applied for Southern Calamari in SA and be extended for use in other fishery jurisdictions. An assessment program that provides confident management advice, such as TACC setting, will maximise resource use across all sectors by establishing a robust stock assessment that increases certainty in stock abundance and allows sustainable fishing strategies to be developed.
Objectives: 1. Review global cephalopod assessments to identify potential assessment methods for Southern Calamari and how environmental variables could be incorporated. 2. Evaluate the suitability of available fishery-dependent and fishery-independent data from the SG and GSV prawn fisheries to develop recruitment indices. 3. Develop Southern Calamari growth models for SG and GSV and evaluate the influence of environment on seasonal growth rates. 4. Outline the most suitable and cost-effective assessment program option for Southern Calamari in SG and GSV Read moreRead less
Reducing Colorectal Cancer Burden In Young Adults: Precision Prevention And Early Detection
Funder
National Health and Medical Research Council
Funding Amount
$1,449,800.00
Summary
Bowel cancer rate in young adults before age 50 is increasing worldwide including Australia. Since it is impossible to screen everyone, it is critical to identify who is likely to develop the disease, to optimise screening. Using the world's largest resource for young-onset bowel cancer, I will conduct studies to generate high-quality evidence to inform how to best prevent bowel cancer in young adults and translate into the policy and practice, to reduce colorectal cancer burden in young adults.
Towards Healthy And Sustainable Freshwater Fish Populations – Assessing Genetic Health Of Priority Fish Species To Inform Management
Funder
Fisheries Research and Development Corporation
Funding Amount
$793,355.00
Summary
There are at least four clear needs supporting the proposal, and these are separated below.
1) Genetic health is important for healthy fisheries. A genetically healthy population has good natural recruitment, connectivity to adjacent populations to promote gene flow, sufficient genetic diversity (this relates directly to adaptive potential) and low inbreeding. If genetic health is eroded, populations are less resilient to anthropogenic and natural impacts, affecting their persistence o ....There are at least four clear needs supporting the proposal, and these are separated below.
1) Genetic health is important for healthy fisheries. A genetically healthy population has good natural recruitment, connectivity to adjacent populations to promote gene flow, sufficient genetic diversity (this relates directly to adaptive potential) and low inbreeding. If genetic health is eroded, populations are less resilient to anthropogenic and natural impacts, affecting their persistence over the long term.
2) Public investment to support healthy fisheries is significant. There is continuing extensive investment in native fish protection and enhancement, including more than $13B to the MDB under the Basin Plan to restore populations and recover ecosystem function. The relative outcomes of these efforts need to be evaluated to ensure the greatest benefits from public investment.
3) Fish stocking is a key component of recovery efforts. Millions of hatchery fish have been stocked throughout Australian waterways in the last two decades. There are limited data on the impacts of stocked fish on the genetic health of wild populations, but our recent FishGen research indicates issues with using closely related and inbred broodfish within hatcheries.
4) The project will help maintain and improve the genetic health of Australia’s fisheries assets. By providing hatcheries with information to maximise the genetic health of stocked fish, the work will minimise negative impacts on wild populations. This includes (i) informing on minimum population size and geographic location for broodfish sampling to capture appropriate wild genetic diversity, and (ii) identifying the best broodfish combinations within and across hatcheries to avoid inbreeding and promote health of stocked fish. This will help to build natural genetic resilience so that populations can adapt to rapidly changing environments under climate change.
The work will promote the long-term sustainability of wild fish populations in freshwater ecosystems by protecting the genetic integrity of wild populations. This will contribute to realised economic benefits for recreational and commercial fishing, tourism, cultural and mental-health in communities in regional Australia.
Objectives: 1. Advance and improve hatchery practices to ensure high quality broodfish are stocked to maintain the genetic health and persistence of wild fish populations. 2. Use genomic and other existing complimentary datasets (stocking records, otolith microchemistry, telemetry) and advanced analytical approaches to track the movements of stocked golden perch, Murray cod and silver perch from their released locations and to inform the Status of Australian Fish Stocks (SAFS). Read moreRead less