The secret of tiny hand movements to feel and manipulate objects. This study aims to reveal some of the fundamental sensory mechanisms underlying the uniquely human ability to manipulate objects and use tools. Signals from touch receptors are crucial for controlling grip forces so that delicate objects are held without slipping, or being crushed by excessive force. Yet we know little about how such sensory information is obtained and how it is used for the motor control. By analysing hand moveme ....The secret of tiny hand movements to feel and manipulate objects. This study aims to reveal some of the fundamental sensory mechanisms underlying the uniquely human ability to manipulate objects and use tools. Signals from touch receptors are crucial for controlling grip forces so that delicate objects are held without slipping, or being crushed by excessive force. Yet we know little about how such sensory information is obtained and how it is used for the motor control. By analysing hand movements during object manipulation and recording sensory signals from single human nerve fibres we will investigate how certain types of movement shape richness of available sensory information. This knowledge will facilitate the development of next generation sensory-controlled prosthetics and robotic manipulators.Read moreRead less
A Multi-national Trial To Predict Treatment Response In Subtypes Of Depression
Funder
National Health and Medical Research Council
Funding Amount
$387,489.00
Summary
Treatment of MDD using trial and error can have serious consequences. It can prolong the patient’s suffering (depression is associated with substantial morbidity, and mortality), prolong their absence from work and other productive activity and increase the burden on their family-carers. This multi-national study will collect genetics, brain function and behavioural data from a large number of participants, allowing for sensitive predictors of response to be determined.
Functional Assessment of Head-eye Coordination during Driving. 238 people per 100,000 population were hospitalized and 9 people per 100,000 died as a result of road-transport related injury in Australia in 2002. We will address this issue by assessing the head eye coordination strategies for young drivers, for proficient drivers and for aged drivers to determine those behaviors and strategies that are associated with various levels of performance. This insight could be affectively communicated t ....Functional Assessment of Head-eye Coordination during Driving. 238 people per 100,000 population were hospitalized and 9 people per 100,000 died as a result of road-transport related injury in Australia in 2002. We will address this issue by assessing the head eye coordination strategies for young drivers, for proficient drivers and for aged drivers to determine those behaviors and strategies that are associated with various levels of performance. This insight could be affectively communicated to others and would provide the basis for educational material and methods that would improve operator skill, safety, and performance. These individual improvements would provide overall benefits such as improved transport efficiency, reduced accident rates, saved lives and a reduction in related social costs.Read moreRead less
Nodal Power Saving for Disconnected Ad Hoc Sensor Networks. Bushfire, age care and farming is Australia's today and tomorrow.
A key aspect in bushfire control is early detection of ignitions by spreading miniature low power sensors in a large potential area in an ad hoc fashion and localizing. Response to panic alarm buttons by retirees in a retirement village where they are free to walk around while their location is monitored in real time using a wireless tag they carry to transmit data re ....Nodal Power Saving for Disconnected Ad Hoc Sensor Networks. Bushfire, age care and farming is Australia's today and tomorrow.
A key aspect in bushfire control is early detection of ignitions by spreading miniature low power sensors in a large potential area in an ad hoc fashion and localizing. Response to panic alarm buttons by retirees in a retirement village where they are free to walk around while their location is monitored in real time using a wireless tag they carry to transmit data relating to their physical health(i.e blood pressure, ECG etc). Locating live stocks roaming around in the dairy industry using sensory transmission used for monitoring their statues is vitals for the farmer for improving efficiency.
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SENSORIMOTOR AND AUTONOMIC DYSREGULATION IN HEREDITARY SENSORY AND AUTONOMIC NEUROPATHIES
Funder
National Health and Medical Research Council
Funding Amount
$50,406.00
Summary
Specific genetic mutations can lead to widespread changes in the body. Here we are looking at the congenital Hereditary and Sensory Autonomic Neuropathies, the most common of which primarily affects Eastern European Jews. Affected individuals have difficulty walking and controlling their blood pressure, and also have an indifference to pain. This series of experiments aims to increase our understanding of the underlying neurophysiological disturbances.
The Role Of Corticothalamic Feedback On The Response Dynamics Of Thalamic Neurons
Funder
National Health and Medical Research Council
Funding Amount
$351,852.00
Summary
A fundamental question in neuroscience is how the brain selectively processes sensory information to generate a reliable representation of the world. Positioned in the centre of the brain, the thalamus plays a key role in sensory processing. This project investigates how the interaction between thalamus and cortex shapes the selection and gating of sensory information. This is a fundamental question in basic neuroscience with the potential to increase our knowledge about attentional deficits.
The effect of multisensory and sensory-motor training on auditory accommodation. Learning to use a hearing aid or cochlear implant requires the brain to make adaptive changes to the new type of sensory information provided to the ears. This project examines what drives this accommodation and how we may accelerate the process and maximise its benefits by training so that listeners are able to make better use of these devices.
A New Clinical Tool To Assess Fitness-to-drive In Obstructive Sleep Apnea
Funder
National Health and Medical Research Council
Funding Amount
$727,963.00
Summary
Obstructive sleep apnoea (OSA) affects 1 in 4 middle aged adults. OSA results in impaired neurobehavioral function, excessive sleepiness, and more than 2-fold increased motor vehicle crash risk and workplace accidents. However, not all patients are impaired and identifying patients at risk is a daily clinical challenge. This project proposes new and simple measures that can accurately identify patients with OSA who are most vulnerable to alertness failure and motor vehicle accident risk.
Peripheral and central mechanisms of sensory coding and integration. The research described in this proposal seeks to provide generic answers to fundamental questions about sensory processes, the nature of perceptual experience, and how these are subserved by the nervous system. The study of inter-sensory interactions in perception has the potential to be incorporated into the development of virtual reality-type computer-based technologies. The neurophysiology research will provide basic informa ....Peripheral and central mechanisms of sensory coding and integration. The research described in this proposal seeks to provide generic answers to fundamental questions about sensory processes, the nature of perceptual experience, and how these are subserved by the nervous system. The study of inter-sensory interactions in perception has the potential to be incorporated into the development of virtual reality-type computer-based technologies. The neurophysiology research will provide basic information that has the potential to deepen our understanding, and even enhance possible treatment, of neurological conditions that involve sensory systems.Read moreRead less
Motor problems, ranging from clumsiness to cerebral palsy, are one of the most common adverse outcomes in children born early. This study will investigate the motor development of children born <30 weeks’ gestation compared with peers born at term from birth to 5 years. We will determine whether early clinical evaluations or neuroimaging in the newborn period can predict later motor impairment at 5 years to be able to identify those who will benefit most from early intervention.