The Role Of Corticothalamic Feedback On The Response Dynamics Of Thalamic Neurons
Funder
National Health and Medical Research Council
Funding Amount
$351,852.00
Summary
A fundamental question in neuroscience is how the brain selectively processes sensory information to generate a reliable representation of the world. Positioned in the centre of the brain, the thalamus plays a key role in sensory processing. This project investigates how the interaction between thalamus and cortex shapes the selection and gating of sensory information. This is a fundamental question in basic neuroscience with the potential to increase our knowledge about attentional deficits.
Peripheral and central mechanisms of sensory coding and integration. The research described in this proposal seeks to provide generic answers to fundamental questions about sensory processes, the nature of perceptual experience, and how these are subserved by the nervous system. The study of inter-sensory interactions in perception has the potential to be incorporated into the development of virtual reality-type computer-based technologies. The neurophysiology research will provide basic informa ....Peripheral and central mechanisms of sensory coding and integration. The research described in this proposal seeks to provide generic answers to fundamental questions about sensory processes, the nature of perceptual experience, and how these are subserved by the nervous system. The study of inter-sensory interactions in perception has the potential to be incorporated into the development of virtual reality-type computer-based technologies. The neurophysiology research will provide basic information that has the potential to deepen our understanding, and even enhance possible treatment, of neurological conditions that involve sensory systems.Read moreRead less
How do bees orchestrate smooth landings? The results should pave the way for the development of novel, biologically inspired strategies for the control of landing in unmanned aerial vehicles. Endowing aircraft with the capability of autonomous flight and landing has been a major challenge in engineering technology. There is now considerable interest, nationally and world wide, in the development of small, intelligent, autonomous airborne vehicles for application in a number of areas of defense, ....How do bees orchestrate smooth landings? The results should pave the way for the development of novel, biologically inspired strategies for the control of landing in unmanned aerial vehicles. Endowing aircraft with the capability of autonomous flight and landing has been a major challenge in engineering technology. There is now considerable interest, nationally and world wide, in the development of small, intelligent, autonomous airborne vehicles for application in a number of areas of defense, surveillance and space exploration. The proposed research will help Australia maintain a leading edge in uncovering important biological principles of flight control that can be translated into useful technological applications.Read moreRead less
Complex Motion Processing in Primate Visual Cortex. As we move through the world, a dynamic visual image is projected onto our retinas. The pattern of movement in the retinal image contains information about three-dimensional structure in the environment and the time of impending collisions. Our visual systems are expert at exploiting this information, enabling us to navigate through complex visual environments at a level far beyond the most sophisticated artificial systems. We plan to investiga ....Complex Motion Processing in Primate Visual Cortex. As we move through the world, a dynamic visual image is projected onto our retinas. The pattern of movement in the retinal image contains information about three-dimensional structure in the environment and the time of impending collisions. Our visual systems are expert at exploiting this information, enabling us to navigate through complex visual environments at a level far beyond the most sophisticated artificial systems. We plan to investigate complex motion processing in the primate brain by recording the responses of neurons in identified regions of the visual cortex of macaque monkeys to a range of behaviourally relevant motion stimuli.Read moreRead less
Moving between day and night: Navigational strategies and foraging costs of temporal niche partitioning. This study involves fundamental research to identify the navigational strategies and the foraging cost in animals that occupy different temporal niches. It will make use of the unique research opportunities in Australia, by working with endemic fauna that allows scientists to address questions that would otherwise be hard to answer. The project will introduce the novel technique of differenti ....Moving between day and night: Navigational strategies and foraging costs of temporal niche partitioning. This study involves fundamental research to identify the navigational strategies and the foraging cost in animals that occupy different temporal niches. It will make use of the unique research opportunities in Australia, by working with endemic fauna that allows scientists to address questions that would otherwise be hard to answer. The project will introduce the novel technique of differential GPS to track the paths of ants which has the potential to revolutionise the field of insect navigation. Salience-dependent navigational strategies analysed in this study will be of great interest in the field of engineering and robotics.Read moreRead less
Moving to be seen: a comprehensive analysis of movement-based signal design. Papers on visual motion processing and animal signal design regularly feature in major journals, and the programs of international conferences. We can thus be confident that theoretical advances will attract international attention. We will develop further state-of-the-art methods in motion analysis, with our overall approach likely to serve as a framework for future research programs, although our techniques will have ....Moving to be seen: a comprehensive analysis of movement-based signal design. Papers on visual motion processing and animal signal design regularly feature in major journals, and the programs of international conferences. We can thus be confident that theoretical advances will attract international attention. We will develop further state-of-the-art methods in motion analysis, with our overall approach likely to serve as a framework for future research programs, although our techniques will have applications outside of biology. In addition, we will learn much about the social behaviour of a group of native reptiles about which relatively little is known. Research on the social behaviour of animals is readily comprehended by non-specialists and plays an important role in attracting young people to careers in science.Read moreRead less
Special Research Initiatives - Grant ID: SR0354726
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
NETVISION: AUSTRALIA'S NATIONAL VISION RESEARCH NETWORK. Vision is the most important human sense. Visual malfunctions pose major health challenges. Vision provides a window into the brain, for studying perception, cognition and consciousness. It is integral to human cultural and social development. It provides opportunities for technological advances in diagnostics, artificial vision, robotics, and surveillance. Vision is therefore crucial to three of the National Priority Areas. The National V ....NETVISION: AUSTRALIA'S NATIONAL VISION RESEARCH NETWORK. Vision is the most important human sense. Visual malfunctions pose major health challenges. Vision provides a window into the brain, for studying perception, cognition and consciousness. It is integral to human cultural and social development. It provides opportunities for technological advances in diagnostics, artificial vision, robotics, and surveillance. Vision is therefore crucial to three of the National Priority Areas. The National Vision Network will create a coherent, interactive and innovative research base in the vision sciences, linked to end-users in areas ranging from the art, entertainment and fashion industries, through health and education, to border protection and counter-terrorism.Read moreRead less
Suction pipette measurements of mammalian rod photoreceptor recovery following intense bleaching exposures. The aim of this project is to discover the events and processes that prevent retinal photoreceptors from recovering instantaneously following the cessation of exposure to extremely bright illumination. Recordings will be made from single rod photoreceptors cells isolated from the mammalian retina. The work will uncover the relative roles of the 'photoproducts' created when rhodopsin abso ....Suction pipette measurements of mammalian rod photoreceptor recovery following intense bleaching exposures. The aim of this project is to discover the events and processes that prevent retinal photoreceptors from recovering instantaneously following the cessation of exposure to extremely bright illumination. Recordings will be made from single rod photoreceptors cells isolated from the mammalian retina. The work will uncover the relative roles of the 'photoproducts' created when rhodopsin absorbs light: e.g. intermediates such as metarhodopsin and opsin. The molecular knowledge obtained will help us to understand why it is that the visual system recovers so slowly after the eye has experienced very intense light.Read moreRead less
The first stage of vision: transduction and adaptation in retinal photoreceptors. The project aims to provide a detailed understanding of the molecular steps involved in the first stage of vision - the conversion of light into a neural signal in the rod and cone photoreceptors of the retina. The significance of this is that it will explain the initial events that enable us to see, and will help explain the deficits that occur when the process fails. The outcome will be a comprehensive understand ....The first stage of vision: transduction and adaptation in retinal photoreceptors. The project aims to provide a detailed understanding of the molecular steps involved in the first stage of vision - the conversion of light into a neural signal in the rod and cone photoreceptors of the retina. The significance of this is that it will explain the initial events that enable us to see, and will help explain the deficits that occur when the process fails. The outcome will be a comprehensive understanding of how our photoreceptors respond with extreme sensitivity, yet great rapidity, and over an enormous range of light intensities, thus endowing us with our remarkable sense of vision.Read moreRead less
Honeybee Navigation: Low-level and Cognitive Mechanisms. Anyone watching a honeybee find its way back home effortlessly after flying several kilometres in search of nectar would know that these insects are excellent navigators, despite their diminutive brains and relatively simple nervous systems. The aim of this proposal is to gain a better understanding of the mechanisms by which bees navigate repeatedly to an attractive food source, and recruit their nestmates to visit it. The findings should ....Honeybee Navigation: Low-level and Cognitive Mechanisms. Anyone watching a honeybee find its way back home effortlessly after flying several kilometres in search of nectar would know that these insects are excellent navigators, despite their diminutive brains and relatively simple nervous systems. The aim of this proposal is to gain a better understanding of the mechanisms by which bees navigate repeatedly to an attractive food source, and recruit their nestmates to visit it. The findings should illuminate important principles of animal navigation, as well as suggest novel strategies for robot navigation.Read moreRead less