Plasticity of gastrointestinal vagal afferents. The aim of this project is to identify how leptin modulates specific subtypes of vagal afferent within the gut and the plasticity of this system under different dietary conditions. This proposed project will substantially increase understanding of the interactions between leptin, known to influence food intake, and vagal afferent satiety signals. It will also increase understanding of how these interactions alter in obesity and ultimately provide t ....Plasticity of gastrointestinal vagal afferents. The aim of this project is to identify how leptin modulates specific subtypes of vagal afferent within the gut and the plasticity of this system under different dietary conditions. This proposed project will substantially increase understanding of the interactions between leptin, known to influence food intake, and vagal afferent satiety signals. It will also increase understanding of how these interactions alter in obesity and ultimately provide targets and/or concepts for the pharmacotherapy of obesity.Read moreRead less
Central pathways regulating visceral pain. This project aims to investigate the neural pathways within the spinal cord and brain processing colorectal pain perception. The project aims to identify the spinal cord neurons relaying colorectal signalling into the brain and the influence of descending modulation from the brainstem upon these pathways. The outcomes will greatly benefit fundamental understanding of the central pathways processing visceral pain.
Discovery Early Career Researcher Award - Grant ID: DE120100907
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
The brain, maths and space: their interaction in health and disease. This project investigates how thinking about numbers affects how we think about the space that surrounds us - and vice versa. Investigations of commonalities in the neural and cognitive processing of space and numbers may lead to the development of innovative therapies for people suffering from attentional disorders after brain damage.
Discovery Early Career Researcher Award - Grant ID: DE140100750
Funder
Australian Research Council
Funding Amount
$395,106.00
Summary
Associative learning and fluid intelligence: Computational and neurogenetic analyses. This project investigates genetic contributions to associative learning, one of our most fundamental abilities. Associative learning allows us to navigate in our environment, predict future events and make appropriate decisions. Electrophysiological measures will be used to study learning processes precisely and to investigate their relationship to polymorphisms in genes that regulate neural function. This rese ....Associative learning and fluid intelligence: Computational and neurogenetic analyses. This project investigates genetic contributions to associative learning, one of our most fundamental abilities. Associative learning allows us to navigate in our environment, predict future events and make appropriate decisions. Electrophysiological measures will be used to study learning processes precisely and to investigate their relationship to polymorphisms in genes that regulate neural function. This research will further understanding of the mechanisms that generate individual differences in learning ability and will have applications for educational techniques and behavioural interventions.Read moreRead less