Motion and Spatial Coding in Vision. The results of this project will have implications for the design and implementation of artificial visual systems. Completion of this project will depend upon international collaboration - forging links between a young Australian investigator and outstanding overseas scientists as well as providing excellent training opportunities. Subsequent publication of the research in top-ranking international journals will further promote Australian science abroad.
Insights from brain imaging to study the neural basis of cognition. This project aims to address a major challenge - the need for a better understanding of the basis for human cognition. Humans have a unique capacity for diverse, complex, thought and behaviour. To achieve this our brains need to rapidly and flexibly reconfigure, directing attention to different aspects of the world moment-to-moment as we think and act. The project will combine innovative analysis methods with state-of-the-art n ....Insights from brain imaging to study the neural basis of cognition. This project aims to address a major challenge - the need for a better understanding of the basis for human cognition. Humans have a unique capacity for diverse, complex, thought and behaviour. To achieve this our brains need to rapidly and flexibly reconfigure, directing attention to different aspects of the world moment-to-moment as we think and act. The project will combine innovative analysis methods with state-of-the-art neuroimaging and brain stimulation to understand how key brain regions drive this process. Insights from this project will link brain activation to behaviour, improve insights from brain imaging, and contribute a better understanding of the neural basis of cognition. Such insights can ultimately benefit the development of evidence based approaches to key areas of public concern such as health and education.Read moreRead less
Structural And Functional Analysis Of A Cancer-linked Co-regulator Complex
Funder
National Health and Medical Research Council
Funding Amount
$729,571.00
Summary
We seek to understand the mechanisms by which genes are switched on and off throughout our lifetime. A number of multi-component protein machines are involved in this process but their make-up and mechanism of action is not understood. We will investigate the structure and function of one of these machines that has been strongly linked to cancer.
Neural mechanisms for human form perception. This project aims to determine if there is a single cortical mechanism underlying the human ability to discriminate and recognise objects. It has been speculated that different classes of objects, or forms require different processes. Demonstrating a single process would be a significant advance towards understanding the neural mechanisms giving rise to our ability to segment visual fields into meaningful objects and background. This research provides ....Neural mechanisms for human form perception. This project aims to determine if there is a single cortical mechanism underlying the human ability to discriminate and recognise objects. It has been speculated that different classes of objects, or forms require different processes. Demonstrating a single process would be a significant advance towards understanding the neural mechanisms giving rise to our ability to segment visual fields into meaningful objects and background. This research provides a means for testing models of the neural interactions thought to be generating human form perception and will help us discover how the visual cortex converts raw sensory input into object and form perception.Read moreRead less
Benefit Of 2D-strain Surveillance In Improving Cardiovascular Outcomes In Cancer Patients Undergoing Cardiotoxic Chemotherapy
Funder
National Health and Medical Research Council
Funding Amount
$2,391,979.00
Summary
Cancer survivors are susceptible to heart failure (HF) caused by heart muscle damage from chemotherapy. The current testing for this problem is based on a measure that cannot identify minor changes of cardiac function. Cardiac strain is a sensitive new marker of cardiac function which is predictive of overt dysfunction & HF. This study seeks to identify whether strain can be used to assign treatments that lead to improved cardiac function and are eventually associated with a reduction in HF.
Special Research Initiatives - Grant ID: SR0354793
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
A Neural Network: Understanding Brain Function. This proposal focuses on the mechanisms that regulate brain function, particularly those underpinning the changes in circuitry (plasticity) caused by altered inputs. As such, its core goal is to create an interface between researchers in the neurosciences, computational modelling, robotics and cognitive sciences in order to facilitate optimum collaborative interactions, identify key research questions and promote training opportunities across a mul ....A Neural Network: Understanding Brain Function. This proposal focuses on the mechanisms that regulate brain function, particularly those underpinning the changes in circuitry (plasticity) caused by altered inputs. As such, its core goal is to create an interface between researchers in the neurosciences, computational modelling, robotics and cognitive sciences in order to facilitate optimum collaborative interactions, identify key research questions and promote training opportunities across a multidisciplinary spectrum. This will drive an integrated and accelerated program of discovery and technological development, enhancing Australia's leadership in this crucial field and helping to highlight new biotechnology opportunities and capture social and economic benefits for the nation. Read moreRead less
Discovery And Development Of Better Pain Treatments
Funder
National Health and Medical Research Council
Funding Amount
$9,613,850.00
Summary
Many forms of pain remain poorly treated, leading to significant quality of life and economic losses. This Program grant will discover and characterise new peptides from cone snails and spiders that modulate specific channels in nerves that are critical to the transmission of pain signals to the brain. Using advanced chemical and structural approaches, promising leads will be optimised for potency and stability and evaluated in disease and pathway-specific models of pain to establish their clini ....Many forms of pain remain poorly treated, leading to significant quality of life and economic losses. This Program grant will discover and characterise new peptides from cone snails and spiders that modulate specific channels in nerves that are critical to the transmission of pain signals to the brain. Using advanced chemical and structural approaches, promising leads will be optimised for potency and stability and evaluated in disease and pathway-specific models of pain to establish their clinical potential.Read moreRead less
ARC Centre of Excellence - Vision Science. This Centre will generate important new knowledge of the performance, logic and stability of vision and visual behaviour. This knowledge will help reduce the burden of vision impairment in Australia, increasing productivity, promoting healthy ageing and reducing the community costs of visual impairment (ca. $9.85 billion in 2004). The knowledge produced will also make possible world-class innovations in robotics, leading to novel automated vision system ....ARC Centre of Excellence - Vision Science. This Centre will generate important new knowledge of the performance, logic and stability of vision and visual behaviour. This knowledge will help reduce the burden of vision impairment in Australia, increasing productivity, promoting healthy ageing and reducing the community costs of visual impairment (ca. $9.85 billion in 2004). The knowledge produced will also make possible world-class innovations in robotics, leading to novel automated vision systems with applications in industry and national security. Other knowledge will develop novel diagnostic technologies, for application in health delivery.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0882345
Funder
Australian Research Council
Funding Amount
$650,000.00
Summary
A 3.0 Tesla MRI system for human cognitive neuroscience research. For the first time scientists are beginning to reveal the complex relationship between human brain function and behaviour. These advances have stemmed almost exclusively from the development of sophisticated brain scanning techniques that provide high-resolution images of physiological changes associated with perceptual, cognitive and motor behaviours. This application seeks support for a state-of-the-art scanner to obtain high-re ....A 3.0 Tesla MRI system for human cognitive neuroscience research. For the first time scientists are beginning to reveal the complex relationship between human brain function and behaviour. These advances have stemmed almost exclusively from the development of sophisticated brain scanning techniques that provide high-resolution images of physiological changes associated with perceptual, cognitive and motor behaviours. This application seeks support for a state-of-the-art scanner to obtain high-resolution images of the brain as healthy adults perceive, think, learn, remember and decide. The facility will enable Australian scientists to understand the complex links between brain and behaviour in health and disease.Read moreRead less
Beyond the Beach: What it means to be Australian - A critical analysis of national, transgenerational, multicultural and self perspectives. The question ?What does it mean to be Australian?? raises issues of deep significance about our values, goals, loyalties, behaviours, and international image. Identity conceptions are fundamental to diverse national interest issues (e.g., social cohesion, multiculturalism, defence, promoting industry, social action/reform, immigration) and imagining our futu ....Beyond the Beach: What it means to be Australian - A critical analysis of national, transgenerational, multicultural and self perspectives. The question ?What does it mean to be Australian?? raises issues of deep significance about our values, goals, loyalties, behaviours, and international image. Identity conceptions are fundamental to diverse national interest issues (e.g., social cohesion, multiculturalism, defence, promoting industry, social action/reform, immigration) and imagining our future. This study will characterise: national identity; personal, ethnic, generational, regional and gender commonalities and variations; preferred futures; and moderating influences on identifying as Australian. Outcomes include new knowledge about contemporary national identity, multi-identity constructions, and processes underpinning identity formation; and advances in identity theory/research that will inform social, economic, and educational policy and practice.Read moreRead less