Neural plasticity in older adult human vision. This project aims to expand our understanding of age related changes in brain function, specifically plasticity. The project will increase knowledge of the role of an inhibitory neurotransmitter GABA in visual plasticity. Expected outcomes include new knowledge regarding the regulation of brain function in adulthood, enabling future research and planning for societal benefit to older Australia.
Resolving multi-sensory conflict as we age: audio-visual integration and the role of normal and abnormal sensory decline. Australia has an ageing population. Even the healthiest older individuals undergo some deterioration of vision and hearing, however, these senses are almost invariably studied in isolation. The real world is multisensory. This project will enhance our knowledge of how ageing impacts on the interpretation of visual and auditory information regarding the timing and location of ....Resolving multi-sensory conflict as we age: audio-visual integration and the role of normal and abnormal sensory decline. Australia has an ageing population. Even the healthiest older individuals undergo some deterioration of vision and hearing, however, these senses are almost invariably studied in isolation. The real world is multisensory. This project will enhance our knowledge of how ageing impacts on the interpretation of visual and auditory information regarding the timing and location of objects; essential precursors to many real world tasks, for example: driving, interpreting speech, and hazard avoidance. This knowledge is essential for the optimisation of audio-visual environments for the elderly, and for the development of tools to improve performance in the presence of sensory decline due to age-related eye disease.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0882889
Funder
Australian Research Council
Funding Amount
$150,000.00
Summary
History, the archives and new technologies: developing the Australian women's archives project. This project will create and define generic tools and services to increase the productivity of those involved with the creation, maintenance and use of source material for humanities research. It will provide a pathway to move this infrastructure onto a more sustainable footing and address issues of information overload, authority and quality facing researchers in the networked digital age. This imper ....History, the archives and new technologies: developing the Australian women's archives project. This project will create and define generic tools and services to increase the productivity of those involved with the creation, maintenance and use of source material for humanities research. It will provide a pathway to move this infrastructure onto a more sustainable footing and address issues of information overload, authority and quality facing researchers in the networked digital age. This imperative is seen by scholars and representatives of the nation's major collecting institutions as a primary limiting factor in the contemporary research environment. The project will enhance Australia's reputation as a world leader in the development of web-based information infrastructure to support research and scholarship.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0347122
Funder
Australian Research Council
Funding Amount
$200,000.00
Summary
Australian Women's Archives Project (AWAP). Australian Women's Archives Project aims to enhance infrastructure for researchers in the field of women's and gender history by constructing appropriate data bases and a range of other electronic sources of information, and by improving the preservation and accessibility of records and archives relevant to this prominent and growing field. Project outcomes will include support for the production of cutting edge academic historical works and simultaneo ....Australian Women's Archives Project (AWAP). Australian Women's Archives Project aims to enhance infrastructure for researchers in the field of women's and gender history by constructing appropriate data bases and a range of other electronic sources of information, and by improving the preservation and accessibility of records and archives relevant to this prominent and growing field. Project outcomes will include support for the production of cutting edge academic historical works and simultaneously, the significant contribution of an essential information resource base for Australian women.
The Australian Women's Archives Project employs innovative technologies and adheres to state-of-the-art international standards for electronic management of historical information. The roles of AWAP's Chief Investigators reflect the use of these new forms of information management: CIs both create and utilise the products of each others' collaborative historical research.
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Creating perceptual experts in Australia's policing and security agencies. This project aims to create the next generation of experts in Australia’s policing and national security agencies, by improving crime scene evidence interpretation. Agencies are under pressure to develop more rigorous training practices that go beyond mere intuition and tradition. This project will use a novel approach that directs learning toward the most diagnostic perceptual cues. Expected outcomes include a solid empi ....Creating perceptual experts in Australia's policing and security agencies. This project aims to create the next generation of experts in Australia’s policing and national security agencies, by improving crime scene evidence interpretation. Agencies are under pressure to develop more rigorous training practices that go beyond mere intuition and tradition. This project will use a novel approach that directs learning toward the most diagnostic perceptual cues. Expected outcomes include a solid empirical basis for national training programs designed to create experts that are accurate, reliable, and continuously improving. Improving the training of experts will ensure the integrity of forensics as evidentiary tools available to police, lead to more reliable courtroom convictions and help safeguard Australia from terrorism and crime.Read moreRead less
The Molecular Basis For Target Selection In The Central Nervous System By Sensory Axons
Funder
National Health and Medical Research Council
Funding Amount
$251,325.00
Summary
The normal function of the brain depends upon the specific connections that nerve cells make with each other. These connections are set up in the developing embryo when nerve cells send out long processes - axons - which grow towards their synaptic targets. How axons select their correct targets from amongst the millions of alternatives in the developing brain is unknown. A better understanding of this problem will help us develop therapies to assist regenerating axons re-establish correct conne ....The normal function of the brain depends upon the specific connections that nerve cells make with each other. These connections are set up in the developing embryo when nerve cells send out long processes - axons - which grow towards their synaptic targets. How axons select their correct targets from amongst the millions of alternatives in the developing brain is unknown. A better understanding of this problem will help us develop therapies to assist regenerating axons re-establish correct connections following injury to the brain or spinal cord. We propose to use a simple model system, the embryo of the fruitfly Drosophila, to find molecules that are involved in this process of neuron target recognition - ' axon targeting' molecules - and to study how they work. Drosophila can be genetically manipulated in ways not possible in higher animals. Furthermore the simplicity of its nervous system means that we can determine the connections of individual nerve cells with a high degree of precision. In the first part of our project, we will examine Drosophila embryos that carry mutations in genes suspected to code for targeting molecules. We will stain individual sensory nerve cells in these embryos with dyes to reveal the anatomy of their axons in the brain. If sensory axons terminate abnormally in the brain of a given mutant, the affected gene is likely to code for an axon targeting molecule. In the second part of the study, we will investigate the functions of candidate axon targeting molecules using two approaches. Firstly, we will seek to determine whether the molecule acts in the sensory axons or in their target cells. Secondly, we will use time-lapse microscopy to study how the homing behaviour of the sensory axons is affected in mutant embryos. The results of these studies will lead us closer to an answer to the question: How do axons recognise their specific target cells in the brain?Read moreRead less
ARC Centre of Excellence - Vision Science. This Centre will generate important new knowledge of the performance, logic and stability of vision and visual behaviour. This knowledge will help reduce the burden of vision impairment in Australia, increasing productivity, promoting healthy ageing and reducing the community costs of visual impairment (ca. $9.85 billion in 2004). The knowledge produced will also make possible world-class innovations in robotics, leading to novel automated vision system ....ARC Centre of Excellence - Vision Science. This Centre will generate important new knowledge of the performance, logic and stability of vision and visual behaviour. This knowledge will help reduce the burden of vision impairment in Australia, increasing productivity, promoting healthy ageing and reducing the community costs of visual impairment (ca. $9.85 billion in 2004). The knowledge produced will also make possible world-class innovations in robotics, leading to novel automated vision systems with applications in industry and national security. Other knowledge will develop novel diagnostic technologies, for application in health delivery.Read moreRead less
Bio-inspired camouflage to prevent shark attacks on surfers. Bio-inspired camouflage to prevent shark attacks on surfers. This project aims to develop a new shark deterrent technology to protect surfers and paddlers. Shark attacks are physically and emotionally devastating for the victims, and make the community disproportionately afraid. Surfers are at most risk of attack, but current surfboard-mounted deterrents are ineffective and not widely used. This project will build on the recent discove ....Bio-inspired camouflage to prevent shark attacks on surfers. Bio-inspired camouflage to prevent shark attacks on surfers. This project aims to develop a new shark deterrent technology to protect surfers and paddlers. Shark attacks are physically and emotionally devastating for the victims, and make the community disproportionately afraid. Surfers are at most risk of attack, but current surfboard-mounted deterrents are ineffective and not widely used. This project will build on the recent discovery that white sharks do not attack counter-illuminated (light emitting) seal-shaped decoys, and use new information about shark vision to understand why this ‘camouflage’ is so successful. This will also help to protect threatened shark species by reducing reliance on culling programs to keep people safe in the water.Read moreRead less
Design and Analysis of Optimal Algorithms for Automated Perimetry. Australian demographic studies reveal that visual impairment contributes significantly to disability in the elderly. Glaucoma, the second leading cause of blindness in developed nations, may be slowed if detected early, however recent studies estimate 50% of Australians with glaucoma are undiagnosed. Automated perimetry is used to detect and track such vision loss, but perimetry algorithms perform poorly. This project will design ....Design and Analysis of Optimal Algorithms for Automated Perimetry. Australian demographic studies reveal that visual impairment contributes significantly to disability in the elderly. Glaucoma, the second leading cause of blindness in developed nations, may be slowed if detected early, however recent studies estimate 50% of Australians with glaucoma are undiagnosed. Automated perimetry is used to detect and track such vision loss, but perimetry algorithms perform poorly. This project will design and analyse new algorithms with superior accuracy and efficiency, improving detection and monitoring of vision loss. Enhanced tools for community vision screening will also result, crucial for the ARC's priority goals of ?ageing well, ageing productively? and ?preventative healthcare?Read moreRead less
ARC Research Network for Enabling Human Communication. The Human Communication Network promotes interdisciplinary research in speech, language, and sound by and between humans and machines. The network connects leading and emerging researchers across disciplines, exploits previously unrecognised intersections, supports interdisciplinary graduate training and exchanges, provides database storage infrastructure, and consults with industry and government to set, not follow, research agendas. By ge ....ARC Research Network for Enabling Human Communication. The Human Communication Network promotes interdisciplinary research in speech, language, and sound by and between humans and machines. The network connects leading and emerging researchers across disciplines, exploits previously unrecognised intersections, supports interdisciplinary graduate training and exchanges, provides database storage infrastructure, and consults with industry and government to set, not follow, research agendas. By generating an explosion of new approaches and knowledge, the network will build Australia's reputation as a leader in communication science and technology via advances in automatic speech recognition, distress call monitoring, hearing prostheses, web interfaces, and data retrieval and data mining systems.Read moreRead less