Testing The Imprecision Hypothesis Of Chronic Pain.
Funder
National Health and Medical Research Council
Funding Amount
$788,984.00
Summary
Pain usually occurs when something triggers activity in danger receptors, which are all over the body. The brain receives a huge amount of other sensory input too, which tells the brain what was happening when the danger arose. The brain imprints this sensory barrage and uses it as an early (painful!) warning system next time. If the imprint is imprecise, then the painful warning occurs in non-dangerous situations. We will test whether imprecise imprinting of the sensory input causes the gradual ....Pain usually occurs when something triggers activity in danger receptors, which are all over the body. The brain receives a huge amount of other sensory input too, which tells the brain what was happening when the danger arose. The brain imprints this sensory barrage and uses it as an early (painful!) warning system next time. If the imprint is imprecise, then the painful warning occurs in non-dangerous situations. We will test whether imprecise imprinting of the sensory input causes the gradual development of chronic debilitating pain.Read moreRead less