Development of a multivariate physiologic state space analysis framework for characterising functional properties of the cardiovascular system. Pathologies of the cardiovascular system arising from heart diseases make a major contribution to morbidity and mortality in the Australian community. This project will provide new diagnostic modalities based on advanced noninvasive bioinstrumentation, signal processing and model-based analytical methods to identify early signs of developing disease or t ....Development of a multivariate physiologic state space analysis framework for characterising functional properties of the cardiovascular system. Pathologies of the cardiovascular system arising from heart diseases make a major contribution to morbidity and mortality in the Australian community. This project will provide new diagnostic modalities based on advanced noninvasive bioinstrumentation, signal processing and model-based analytical methods to identify early signs of developing disease or the acute exacerbation of existing disease. The impact of these new technologies on the early diagnosis and improved triaging of patients in emergency departments is potentially profound and could result in improved healthcare outcomes for the patients and reduced admissions to hospital as well as the development of a substantial international market.Read moreRead less
ARC Centre of Excellence in Biotechnology and Development. The Centre will create a multidisciplinary research team focusing on the molecular mechanisms that drive the specification and differentiation of male germ cells. This research will improve our fundamental understanding of how complex regulatory networks control the expression of a complex phenotype, the spermatozoon. It will also create a platform of knowledge from which we can stimulate the growth of the Australian Biotechnology indust ....ARC Centre of Excellence in Biotechnology and Development. The Centre will create a multidisciplinary research team focusing on the molecular mechanisms that drive the specification and differentiation of male germ cells. This research will improve our fundamental understanding of how complex regulatory networks control the expression of a complex phenotype, the spermatozoon. It will also create a platform of knowledge from which we can stimulate the growth of the Australian Biotechnology industry, the protection of the Australian Environment and the well-being of the Australian people. Key issues for this Centre include testicular cancer, male infertility, contraception, pest animal control, environmental impacts on human health and gene pharming.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH190100022
Funder
Australian Research Council
Funding Amount
$4,787,259.00
Summary
ARC Research Hub for Sustainable Crop Protection. The Hub aims to develop and commercialise an innovative biological alternative to chemical fungicides targeting economically significant diseases of broadacre and horticultural crops. It addresses industry challenges of fungicide resistance, chemical residues in food, off-target effects and environmental harm. It builds on ground-breaking ‘BioClay’ platform to deliver pathogen targeting RNA using clay particles as non-genetically modified crop pr ....ARC Research Hub for Sustainable Crop Protection. The Hub aims to develop and commercialise an innovative biological alternative to chemical fungicides targeting economically significant diseases of broadacre and horticultural crops. It addresses industry challenges of fungicide resistance, chemical residues in food, off-target effects and environmental harm. It builds on ground-breaking ‘BioClay’ platform to deliver pathogen targeting RNA using clay particles as non-genetically modified crop protection. An expert multidisciplinary team uniting science, commercial and social licence pathways ensures industry and consumer uptake advancing $60B Australian Agriculture. The Hub translates to increased productivity, market access and enhanced environmental credentials of Australian food.
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Vulnerability of Australian bats to white-nose syndrome. Australia's unique wildlife is inherently at risk from invasive novel pathogens. White-nose syndrome is an emerging fungal disease that has decimated bat populations across North America. This fungal disease is likely to soon jump continents and also seriously threaten Australia's bat fauna. This project aims to quantify the risk of exposure to this fungus and understand the sensitivity of Australian bat populations to white-nose syndrome ....Vulnerability of Australian bats to white-nose syndrome. Australia's unique wildlife is inherently at risk from invasive novel pathogens. White-nose syndrome is an emerging fungal disease that has decimated bat populations across North America. This fungal disease is likely to soon jump continents and also seriously threaten Australia's bat fauna. This project aims to quantify the risk of exposure to this fungus and understand the sensitivity of Australian bat populations to white-nose syndrome mortality. Expected outcomes include spatially-explicit, species-specific models of vulnerability to white-nose syndrome for bat populations across south-eastern Australia, essential for directing actions to prevent, detect and mitigate the impacts of this potentially catastrophic wildlife disease.Read moreRead less
ARC Centre of Excellence for Innovations in Peptide and Protein Science. The ARC Centre of Excellence for Innovations in Peptide and Protein Science (CIPPS) strives to build a critical understanding of peptides and proteins in order to unleash the potential of these biomolecules for human benefit. We will discover nature’s untapped reservoir of peptides and proteins, decode their structures and functions, and
develop enhanced synthetic technologies to address biology’s next grand challenge—the d ....ARC Centre of Excellence for Innovations in Peptide and Protein Science. The ARC Centre of Excellence for Innovations in Peptide and Protein Science (CIPPS) strives to build a critical understanding of peptides and proteins in order to unleash the potential of these biomolecules for human benefit. We will discover nature’s untapped reservoir of peptides and proteins, decode their structures and functions, and
develop enhanced synthetic technologies to address biology’s next grand challenge—the design of peptides and proteins for targeted scientific, agricultural, biotechnology, animal health and pharmaceutical applications. CIPPS will assemble leading researchers from diverse disciplines to create a sustainable national entity that will drive new Australian industries and train next generation researchers.Read moreRead less