Industrial Transformation Training Centres - Grant ID: IC210100056
Funder
Australian Research Council
Funding Amount
$3,975,864.00
Summary
ARC Training Centre for Next-Gen Technologies in Biomedical Analysis . The Centre for Next-Gen Technologies in Biomedical Analysis will deliver workforce trained in the development of transformative technologies that will rapidly expand the Australian pharmaceutical, diagnostic and defence sector. The university-industry partnership will increase Australia’s manufacturing capability by fast tracking screening, by integrating 3D printing, advanced sensing, big data analytics, machine learning an ....ARC Training Centre for Next-Gen Technologies in Biomedical Analysis . The Centre for Next-Gen Technologies in Biomedical Analysis will deliver workforce trained in the development of transformative technologies that will rapidly expand the Australian pharmaceutical, diagnostic and defence sector. The university-industry partnership will increase Australia’s manufacturing capability by fast tracking screening, by integrating 3D printing, advanced sensing, big data analytics, machine learning and artificial intelligence for the delivery of optimal solutions in diagnosis, treatment and wellbeing. The centre will deliver training in Industry 4.0 skills which will boost early-stage scale-up and accelerate the sector’s supply chain, which is pivotal for the Australian industries to maintain a competitive edge. Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH190100009
Funder
Australian Research Council
Funding Amount
$3,317,500.00
Summary
ARC Research Hub for Microrecycling of battery and consumer wastes . This project aims to transform Australia’s waste and resource recovery industry by equipping it with scientifically developed advanced manufacturing capability, focusing on small-scale processing of materials produced from battery and consumer wastes which would otherwise mostly end up in landfill. The project will deliver new knowledge in high-temperature reactions of waste and selective synthesis techniques to transform waste ....ARC Research Hub for Microrecycling of battery and consumer wastes . This project aims to transform Australia’s waste and resource recovery industry by equipping it with scientifically developed advanced manufacturing capability, focusing on small-scale processing of materials produced from battery and consumer wastes which would otherwise mostly end up in landfill. The project will deliver new knowledge in high-temperature reactions of waste and selective synthesis techniques to transform waste into valuable materials and products, including metallic alloys, oxides and carbon. Expected outcomes include industry adoption of commercially viable technology and processes where low value or complex waste is reformed into higher value materials, creating jobs and significant environmental and social benefits.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC200100022
Funder
Australian Research Council
Funding Amount
$4,883,406.00
Summary
ARC Training Centre for Information Resilience. The proposed centre aims at building workforce capacity in Australian organisations to create, protect and sustain agile data pipelines, capable of detecting and responding to failures and risks across the information value chain in which the data is sourced, shared, transformed, analysed and consumed. Building on strong foundations of responsible data science, the centre will bring together end-users, technology providers, and cutting-edge researc ....ARC Training Centre for Information Resilience. The proposed centre aims at building workforce capacity in Australian organisations to create, protect and sustain agile data pipelines, capable of detecting and responding to failures and risks across the information value chain in which the data is sourced, shared, transformed, analysed and consumed. Building on strong foundations of responsible data science, the centre will bring together end-users, technology providers, and cutting-edge research, to lift the socio-technical barriers to data driven transformation and develop resilient data pipelines capable of delivering game-changing productivity gains that position Australian organisations at the forefront of technology leadership and value creation from data assets. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100148
Funder
Australian Research Council
Funding Amount
$1,350,000.00
Summary
Advanced Nuclear Magnetic Resonance Technologies for Southeast Queensland. This project aims to establish an advanced Nuclear Magnetic Resonance capability and capacity at two of Queenslands' leading research intensive universities. The project expects to enhance the scope and productivity of hundreds of research projects spanning natural products, synthetic, medicinal, materials and environmental science. Expected outcomes include smarter science, more productive collaborations and superior res ....Advanced Nuclear Magnetic Resonance Technologies for Southeast Queensland. This project aims to establish an advanced Nuclear Magnetic Resonance capability and capacity at two of Queenslands' leading research intensive universities. The project expects to enhance the scope and productivity of hundreds of research projects spanning natural products, synthetic, medicinal, materials and environmental science. Expected outcomes include smarter science, more productive collaborations and superior research training, leading to innovative solutions to challenging problems that confront science and society. This investment should provide significant benefits in the form of new knowledge across multiple disciplines, informing the design of future medicines, agrochemicals, materials and other products.
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Eradicating bacterial biofilms with nitroxide-antimicrobial hybrids. This project aims to develop new antimicrobials to address the rise of drug-resistant infections and resilient bacterial communities called biofilms. We aim to break new ground in our fundamental knowledge of antimicrobial mechanisms and exploit this understanding by fusing cellular/molecular microbiology and synthetic chemistry approaches. We seek to gain an in-depth understanding of how nitroxides induce bacterial biofilm dis ....Eradicating bacterial biofilms with nitroxide-antimicrobial hybrids. This project aims to develop new antimicrobials to address the rise of drug-resistant infections and resilient bacterial communities called biofilms. We aim to break new ground in our fundamental knowledge of antimicrobial mechanisms and exploit this understanding by fusing cellular/molecular microbiology and synthetic chemistry approaches. We seek to gain an in-depth understanding of how nitroxides induce bacterial biofilm dispersal, which is critical for the discovery of anti-biofilm molecules that do not fail due to resistance development. These breakthroughs should induce a step-change in our ability to reduce the occurrence of biofilm-related infection in fields ranging from medical and veterinary to biotechnology and agriculture.Read moreRead less
ARC Centre of Excellence for the Digital Child. Our vision is for Australian children to be healthy, educated and connected. This Centre will integrate child health, education, and digital and social connectedness, innovating across disciplines to meet Australia’s ongoing challenges of supporting young children growing up in a rapidly changing digital age. The Centre’s world-leading team investigates children’s digital practices through three interconnected research programs supported by a longi ....ARC Centre of Excellence for the Digital Child. Our vision is for Australian children to be healthy, educated and connected. This Centre will integrate child health, education, and digital and social connectedness, innovating across disciplines to meet Australia’s ongoing challenges of supporting young children growing up in a rapidly changing digital age. The Centre’s world-leading team investigates children’s digital practices through three interconnected research programs supported by a longitudinal family cohort study and children’s technology laboratories. The Centre will address tensions in a contested field to inform government and non-government policy, technology innovation, and develop programs and guidelines for children, families, educators and technology developers. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE200100174
Funder
Australian Research Council
Funding Amount
$425,000.00
Summary
X-Ray Nanolithography Facility: Towards the ultimate resolution. This Project aims to address the need for precise and scalable nanoscale fabrication by establishing a synchrotron-based X-Ray Nanolithography Facility. This Project expects to generate new knowledge in the areas of advanced manufacturing and nanotechnology using an innovative approach that combines coherent lithography and coherent imaging metrology. Expected outcomes of this project include an internationally unique, nationally ....X-Ray Nanolithography Facility: Towards the ultimate resolution. This Project aims to address the need for precise and scalable nanoscale fabrication by establishing a synchrotron-based X-Ray Nanolithography Facility. This Project expects to generate new knowledge in the areas of advanced manufacturing and nanotechnology using an innovative approach that combines coherent lithography and coherent imaging metrology. Expected outcomes of this project include an internationally unique, nationally accessible capability for manufacturing at the nanoscale and for industry-driven collaborative research. This should provide significant benefits across fields that aim to harness the unique properties of engineered nanomaterials to greatly enhance the technologies required to solve global challenges.Read moreRead less
Nano-reactors: Protein cages as reusable scaffolds for designer enzymes. This project aims to develop robust protein cages derived from the coats of viruses to contain heat-stable P450 enzymes, for use as specialised protein bio-catalysts in chemical industries. A valuable chemical precursor of renewable bio-plastics will be produced from seed oils by enzymes, reducing the use of fossil fuels. This synthetic biology approach combines biotechnology, nanotechnology and protein engineering to estab ....Nano-reactors: Protein cages as reusable scaffolds for designer enzymes. This project aims to develop robust protein cages derived from the coats of viruses to contain heat-stable P450 enzymes, for use as specialised protein bio-catalysts in chemical industries. A valuable chemical precursor of renewable bio-plastics will be produced from seed oils by enzymes, reducing the use of fossil fuels. This synthetic biology approach combines biotechnology, nanotechnology and protein engineering to establish a plant-based platform biotechnology for using enzymes as catalysts to make high-value molecules. The project aims to show how to engineer clean, sustainable chemistry in designer nano-environments. This should make synthetic processes more sustainable and enhance advanced chemical manufacturing in Australia.Read moreRead less
Harnessing molecular strain for drug discovery and bioconjugation. Peptides and proteins are increasingly important therapies for the treatment of disease. Nevertheless, the synthesis and optimisation of these high-value compounds still relies primarily on technologies developed decades ago. There is a desperate need for modern strategies to unlock the full potential of peptides and proteins for diverse applications in drug discovery. This interdisciplinary research aims to develop new tools for ....Harnessing molecular strain for drug discovery and bioconjugation. Peptides and proteins are increasingly important therapies for the treatment of disease. Nevertheless, the synthesis and optimisation of these high-value compounds still relies primarily on technologies developed decades ago. There is a desperate need for modern strategies to unlock the full potential of peptides and proteins for diverse applications in drug discovery. This interdisciplinary research aims to develop new tools for the construction and modification of peptides and proteins by harnessing the energy in a unique class of strained molecules. A focus on peptide-based inhibitors of the proteasome, a critical target for modern cancer treatments, should provide future health and economic benefits for the Australian community.Read moreRead less
Advances in Peptide Synthesis: Exploiting Underutilised Functional Groups. The translation of therapeutically-relevant classes of peptides to the clinic is often limited by chemists' ability to synthesise these complex biomolecules efficiently and sustainably. This project aims to develop new tools for the preparation of designer peptides that are broadly inspired by an underutilised reactive group found in naturally-occurring peptide sequences. Expected outcomes encompass health and economic be ....Advances in Peptide Synthesis: Exploiting Underutilised Functional Groups. The translation of therapeutically-relevant classes of peptides to the clinic is often limited by chemists' ability to synthesise these complex biomolecules efficiently and sustainably. This project aims to develop new tools for the preparation of designer peptides that are broadly inspired by an underutilised reactive group found in naturally-occurring peptide sequences. Expected outcomes encompass health and economic benefits for the Australian community, including: the first approach to a class of promising antibiotic peptide natural product analogues, the development of a mild electrochemical approach to peptide modification, and the production of a library of novel amino acids for incorporation into potential antibiotic leads.Read moreRead less