Eco-RESIDE: An Economic Evaluation Of Urban Design As A Means Of Promoting Physical Activity
Funder
National Health and Medical Research Council
Funding Amount
$422,612.00
Summary
The significance of this project lies in the health problem that it seeks to address and the intervention that is being evaluated. Physical inactivity ranks second only to tobacco use in terms of the costs of diseases associated with behavioural risk factors. Declining rates of physical activity have been associated with increasing rates of obesity and overweight in Australian children and adults. The association that one sees between features of the urban environment and physical activity level ....The significance of this project lies in the health problem that it seeks to address and the intervention that is being evaluated. Physical inactivity ranks second only to tobacco use in terms of the costs of diseases associated with behavioural risk factors. Declining rates of physical activity have been associated with increasing rates of obesity and overweight in Australian children and adults. The association that one sees between features of the urban environment and physical activity levels suggests that urban planning guidelines may be a cost-effective means of promoting health and achieving other social objectives such as sustainable use of natural resources. Furthermore, not enough is known about the economic value of investing in health promoting interventions and this project is among the first to measure the costs and benefits of intervening at the environmental level. The information that it provides will be highly useful for local government and health service planners alike.Read moreRead less
Burden Of Disease: Costing An Effective Package Of Care For Mental Disorders
Funder
National Health and Medical Research Council
Funding Amount
$272,735.00
Summary
The Global Burden of Disease project, a WHO-World Bank-Harvard collaboration, presented an unprecedented picture of global health across the developed and developing world, providing much-needed information for planning health services. Health was measured at the population level, and combined the number of life years lost due to death and disablement to give a total amount of life lost per disorder. One surprise of the project was the importance of mental disorders, accounting for 43% of life y ....The Global Burden of Disease project, a WHO-World Bank-Harvard collaboration, presented an unprecedented picture of global health across the developed and developing world, providing much-needed information for planning health services. Health was measured at the population level, and combined the number of life years lost due to death and disablement to give a total amount of life lost per disorder. One surprise of the project was the importance of mental disorders, accounting for 43% of life years lost due to disability in countries like Australia. Service planning to reduce this burden requires knowledge of cost-effective treatments.This project will trial a method used for combining burden and cost-effectiveness data to design an essential package of services to address the treatment shortfall in mental disorders. This research will assist in our understanding of why burden due to mental disorders persists, and the extent to which current treatment knowledge is able to address this burden within existing budgetary constraints. This will be achieved by: 1) detailing the costs and population outcome of current services in Australia for mental disorders, to determine which disorders are currently adequately treated and which disorders require further intervention, 2) calculating the costs and outcome of best practice interventions from clinical practice guidelines, to understand the extent to which current treatment knowledge can reduce burden due to mental disorders, 3) examining the equity consequences of such a package of ideal interventions, with the understanding that the treatment endpoint is not the same for all disorders. This is a secondary analysis, representing a method for translating existing cost and outcome data for individual treatments into their costs and consequences for health planning at the population level.Read moreRead less
Empirical Ethics: Quantification Of Social Preferences For Economic Evaluation In The Health Sector
Funder
National Health and Medical Research Council
Funding Amount
$329,450.00
Summary
Recent studies indicate that there are significant differences between the social 'preferences'-priorities of the population and the priorities implied by health policy and embodied in health economic evaluations of the health sector. For example, members of the public give higher priority to the severely ill even when little can be done for them. The studies suggest that the public would also take into account, inter alia, a number of other factors, including prognosis, health potential and the ....Recent studies indicate that there are significant differences between the social 'preferences'-priorities of the population and the priorities implied by health policy and embodied in health economic evaluations of the health sector. For example, members of the public give higher priority to the severely ill even when little can be done for them. The studies suggest that the public would also take into account, inter alia, a number of other factors, including prognosis, health potential and the social context of the problem. They would not treat program costs in the way economic theory and practice recommends. These issues have been dramatised in the WHO's Evaluation of Health Systems (World Health Report 2000). This assigns a weight of only 0.25 to health improvement and 0.75 to issues of fairness. The proposed study will carry out three tasks. The first is to measure the importance of Australian health-related social preferences which should, potentially, be included in economic evaluation studies. Key values - parameters - including the rate of time preference and the social willingness to pay for an additional year of life will be measured precisely for immediate use. Secondly, the importance of other issues including illness severity, adaptation and prognosis will be tested to determine how these factors should be included in the economic evaluation of health programs. Finally, some general issues related to public versus private funding, egalitarianism and choice will be investigated. Results from interviews and surveys will be integrated in the Assessment of Quality of Life (AQoL) instrument and its user manual.Read moreRead less
NEURONAL RESPONSES ELICITED BY VIEWING HUMAN BODY MOTION AND GESTURE.
Funder
National Health and Medical Research Council
Funding Amount
$135,822.00
Summary
This project aims to study human brain regions active in viewing movements of the body, face and hands, as well as gestures (i.e. movements with meaning). We will map the location of these human motion sensitive brain regions relative to brain areas dealing with other visual functions. We will use a new method of brain scanning (functional MRI) and recordings of the electrical activity of the brain to achieve these goals. Subjects for this project will be epilepsy patients undergoing investigati ....This project aims to study human brain regions active in viewing movements of the body, face and hands, as well as gestures (i.e. movements with meaning). We will map the location of these human motion sensitive brain regions relative to brain areas dealing with other visual functions. We will use a new method of brain scanning (functional MRI) and recordings of the electrical activity of the brain to achieve these goals. Subjects for this project will be epilepsy patients undergoing investigation for seizure surgery at the A and RMC and Royal Children's Hospitals in Melbourne. Functional MRI - a new non-invasive method for studying brain function - will locate the brain structures involved in the detection and analysis of human motion. Recording electrodes are surgically placed inside the brains of these patients in order to find the source of their seizures, and these electrodes will be utilised for this study. A number of facial, hand and body movement and gestural stimuli will be used. First, brain locations responding to face, hand and body movements will be identified. It is predicted that regions sensitive to hand motion could be located near areas known to participate in adjusting the subject's own visually-guided reaching behaviour. Similarly, regions sensitive to facial motion could be located near areas thought to deal with lip-reading. Second, differences in brain activity to gestures and movements of the face and hand will be studied, so as identify brain regions that process increasingly complex information. Third, differences in brain responses to incompatible (e.g. head facing left and moving right) versus compatible human motion will be studied. A brain 'map' with locations of these human motion sensitive regions relative to visually sensitive regions will be generated. These data will not only aid planning for future seizure surgery, but have implications for our understanding of the visual aspects of motor apraxia.Read moreRead less
A Cluster Randomised Trial Of Early Intervention For Chronic Obstructive Pulmonary Disease By Practice Nurse-GP Teams
Funder
National Health and Medical Research Council
Funding Amount
$818,914.00
Summary
Chronic Obstructive Pulmonary Disease (COPD) is a common problem for current or ex smokers but is often undiagnosed. Effective treatment is available so early diagnosis is important. In this study practice nurses will identify patients who are at risk of COPD and undertake case finding. Patients newly diagnosed with COPD will then be offered a novel management intervention involving the GP and practice nurse working in partnership.
Systematic Expansion Of The Clinical Evidence Base In Opioid Prescribing For Refractory Dyspnoea At The End Of Life
Funder
National Health and Medical Research Council
Funding Amount
$414,535.00
Summary
Morphine can relieve breathlessness in the palliative setting. But many important questions remain. What is the best dose, should the dose change over time, do different medications provide the same relief, and how common is dyspnoea in the general population? This three part project will extend our knowledge to answer these questions. Population data will provide critical background to plan best care for future palliative patients distressed by breathlessness.