Combined optical and electrical stimulation of auditory neurons. The bionic ear, which has now helped to improve the hearing of over 200,000 people worldwide, is a great example of Australian innovation success. This project aims to develop the fundamental technology that will underpin the next generation of these devices using a combination of infrared light and electrical signals to stimulate auditory nerves.
Complete blood fractionation using a low-cost microfluidic system. This project aims to understand particle focusing in inertial microfluidic systems to design efficient devices for cell sorting. The field of microfluidics could ultimately advance medical research but device design is primitive. Microfluidic particle separations are not thoroughly simulated before fabrication to predict performance. This project is expected to accelerate progress in design of efficient microfluidic devices. The ....Complete blood fractionation using a low-cost microfluidic system. This project aims to understand particle focusing in inertial microfluidic systems to design efficient devices for cell sorting. The field of microfluidics could ultimately advance medical research but device design is primitive. Microfluidic particle separations are not thoroughly simulated before fabrication to predict performance. This project is expected to accelerate progress in design of efficient microfluidic devices. The knowledge and models developed in this project should help design and develop a microfluidic device for efficient fractionation of complex fluids into valuable components.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE180100688
Funder
Australian Research Council
Funding Amount
$336,446.00
Summary
Nanosensors in artificial cochlea for natural hearing. This project aims to develop a miniaturised and implantable cochlear that closely mimics the human auditory system by utilising advanced microfabrication techniques. This project expects to generate new knowledge in engineering hearing and vestibular hair cells and also on tonotopic organisation of cochlear. Expected outcomes include study of auditory hair cells and development of implantable ear-on-a-chip devices. This project is expected t ....Nanosensors in artificial cochlea for natural hearing. This project aims to develop a miniaturised and implantable cochlear that closely mimics the human auditory system by utilising advanced microfabrication techniques. This project expects to generate new knowledge in engineering hearing and vestibular hair cells and also on tonotopic organisation of cochlear. Expected outcomes include study of auditory hair cells and development of implantable ear-on-a-chip devices. This project is expected to enable low-cost production of highly engineered implant cochlear with great potential for commercialisation.Read moreRead less
Bioinspired Flexible Haptic Memory Materials for Artificial Sensory Nerves. This project aims to develop next generation haptic memory materials for the applications of artificial sensory nerves, which can precisely detect, process and respond to mechanical stimuli. The project expects to achieve this aim by mimicking the functions of biological haptic memory system and integrating highly sensitive tactile sensors and synaptic devices into artificial sensory nerves. The anticipated outcomes wil ....Bioinspired Flexible Haptic Memory Materials for Artificial Sensory Nerves. This project aims to develop next generation haptic memory materials for the applications of artificial sensory nerves, which can precisely detect, process and respond to mechanical stimuli. The project expects to achieve this aim by mimicking the functions of biological haptic memory system and integrating highly sensitive tactile sensors and synaptic devices into artificial sensory nerves. The anticipated outcomes will be new electronic materials for a wide range of end uses in next-generation flexible sensor technologies including healthcare monitoring devices, intelligent soft robotic systems and neural prosthetics.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE200100074
Funder
Australian Research Council
Funding Amount
$418,210.00
Summary
Nanoscale laser cooling in physiological environment. By developing fluorescence pattern-based 3D motion-detection technology in optical tweezers, this project aims to reveal how to achieve nanoscale laser cooling in physiological media. It plans to discover new mechanisms of cooling associated with surface phonons and energy looping in optically trapped lanthanide-doped nanoparticles. Key expected outcomes are technology and a toolset to create interaction between cooled nanoscale objects and b ....Nanoscale laser cooling in physiological environment. By developing fluorescence pattern-based 3D motion-detection technology in optical tweezers, this project aims to reveal how to achieve nanoscale laser cooling in physiological media. It plans to discover new mechanisms of cooling associated with surface phonons and energy looping in optically trapped lanthanide-doped nanoparticles. Key expected outcomes are technology and a toolset to create interaction between cooled nanoscale objects and biological samples. These are expected to create a research area of biological laser refrigeration, enabling intracellular organelles cooling, nanoscale membrane disruption and high sensitivity force-sensing for integrin study for use in single-molecule biophysics and multimodality subcellular sensing.Read moreRead less
Laser-free on-chip super-resolution microscopy. The project aims to develop a compact, cost-effective on-chip super-resolution microscope through an innovative combination of imaging algorithms, optics and integrated photonics. This project addresses limitations in imaging algorithms that increase laser system complexity and constrain imaging speed and applications, as well as nanostructure fabrication issues. Expected outcomes include the discovery of emitter self-interference microscopy, new k ....Laser-free on-chip super-resolution microscopy. The project aims to develop a compact, cost-effective on-chip super-resolution microscope through an innovative combination of imaging algorithms, optics and integrated photonics. This project addresses limitations in imaging algorithms that increase laser system complexity and constrain imaging speed and applications, as well as nanostructure fabrication issues. Expected outcomes include the discovery of emitter self-interference microscopy, new knowledge in imaging, photonics and biophysics, the world’s fastest super-resolution technology, compact on-chip nanoscopy that can be added to existing technology and proof of concept in three areas. Benefits are anticipated in commercialisation, improved photonics devices and usage in biophysics.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE210100692
Funder
Australian Research Council
Funding Amount
$420,000.00
Summary
Multiphysics inertial microfluidics: from fundamentals to applications. Separation of particles and particularly cells is an indispensable process in disease diagnostics, chemical/biological assays and food/chemical industries. This project aims to study the interplay between inertial fluid flow, electricity, and magnetism in microscale for particle separation. The project is expected to establish the fundamental theory underpinning the development of the proposed advanced separation technology. ....Multiphysics inertial microfluidics: from fundamentals to applications. Separation of particles and particularly cells is an indispensable process in disease diagnostics, chemical/biological assays and food/chemical industries. This project aims to study the interplay between inertial fluid flow, electricity, and magnetism in microscale for particle separation. The project is expected to establish the fundamental theory underpinning the development of the proposed advanced separation technology. This disruptive technology is expected to enable the unique, high-performance and high-throughput separation of particles such as cells. The technology will potentially benefit the biomedical and pharmaceutical industries, providing economic opportunities and maintaining high-quality healthcare for Australia.Read moreRead less
Ultra-fast serialised all optical image processing: addressing the electronic bottleneck in the world's fastest camera. Serial time encoded amplified microscopy can capture over a million frames per second. At this rate, a megapixel image would fill a terabyte hard disk in a second. We will use photonics to condense and manipulated the video stream so that only the important features are 'seen', making it practical to process and store on a computer.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE180100030
Funder
Australian Research Council
Funding Amount
$541,705.00
Summary
National facility for nanoscale characterisation of luminescent materials. The project aims to establish a national facility for nanoscale characterisation of advanced optoelectronic materials, including atomically-thin materials, luminescent nanocrystals, metamaterials, and plasmonic nanostructures. The combination of a highly focused electron beam, and novel light detection optics, will enable temperature-dependent, angle, polarisation and time-resolved luminescence analysis with unprecedented ....National facility for nanoscale characterisation of luminescent materials. The project aims to establish a national facility for nanoscale characterisation of advanced optoelectronic materials, including atomically-thin materials, luminescent nanocrystals, metamaterials, and plasmonic nanostructures. The combination of a highly focused electron beam, and novel light detection optics, will enable temperature-dependent, angle, polarisation and time-resolved luminescence analysis with unprecedented resolution. It is expected this will yield discoveries in nanoscale physics and materials science. It will create interdisciplinary collaborations by linking Australian scientists who use high-resolution multimodal characterisation methods to innovate and develop materials and device technologies.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE160101101
Funder
Australian Research Council
Funding Amount
$348,741.00
Summary
Single-Molecule Circuitry for Nanoscale Electronic Devices. The aim of this project is to develop novel methods for forming robust single-molecule circuitry. The use of single molecules in electronics represents the next level of miniaturisation of electronic components, which would enable us to meet the expanding demands of modern technologies and to continue the downscaling trend in electronic devices. This project aims to address the requirements needed to translate single-molecule electronic ....Single-Molecule Circuitry for Nanoscale Electronic Devices. The aim of this project is to develop novel methods for forming robust single-molecule circuitry. The use of single molecules in electronics represents the next level of miniaturisation of electronic components, which would enable us to meet the expanding demands of modern technologies and to continue the downscaling trend in electronic devices. This project aims to address the requirements needed to translate single-molecule electronics from its current status as a fundamental tool to real-world applications. Key approaches will be the use of surface chemistry to develop new methods of wiring single molecules and the integration of robust single-molecule junctions with semiconducting electrodes. The expected project outcomes pave the way for single-molecule electronic and analytical devices.Read moreRead less